PURB (purine rich element binding protein B)

2003-02-01  

Identity

HGNC
LOCATION
7p13
LOCUSID
ALIAS
PURBETA
FUSION GENES

Other Information

Locus ID:

NCBI: 5814
MIM: 608887
HGNC: 9702
Ensembl: ENSG00000146676

Variants:

dbSNP: 5814
ClinVar: 5814
TCGA: ENSG00000146676
COSMIC: PURB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146676ENST00000395699Q96QR8

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45
129337922003Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.28
194966232009Mechanism of strand-specific smooth muscle alpha-actin enhancer interaction by purine-rich element binding protein B (Purbeta).8
244462472014The Purα/Purβ single-strand DNA-binding proteins attenuate smooth-muscle actin gene transactivation in myofibroblasts.5
270647492016Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element-Binding Protein B.2
288345932018Characterization of purine-rich element binding protein B as a novel biomarker in acute myelogenous leukemia prognostication.1

Citation

Dessen P

PURB (purine rich element binding protein B)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41952/purb