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PUS10 (pseudouridylate synthase 10)

Identity

Alias_namesCCDC139
coiled-coil domain containing 139
Alias_symbol (synonym)FLJ32312
Other aliasDOBI
HGNC (Hugo) PUS10
LocusID (NCBI) 150962
Atlas_Id 72400
Location 2p16.1  [Link to chromosome band 2p16]
Location_base_pair Starts at 60940413 and ends at 61017431 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KDM3A (2p11.2) / PUS10 (2p16.1)PUS10 (2p16.1) / CASC15 (6p22.3)PUS10 (2p16.1) / PIK3R4 (3q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PUS10   26505
Cards
Entrez_Gene (NCBI)PUS10  150962  pseudouridylate synthase 10
AliasesCCDC139; DOBI
GeneCards (Weizmann)PUS10
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:60940413-61017431 [Contig_View]  PUS10 [Vega]
TCGA cBioPortalPUS10
AceView (NCBI)PUS10
Genatlas (Paris)PUS10
WikiGenes150962
SOURCE (Princeton)PUS10
Genetics Home Reference (NIH)PUS10
Genomic and cartography
GoldenPath hg38 (UCSC)PUS10  -     chr2:60940413-61017431 -  2p16.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PUS10  -     2p16.1   [Description]    (hg19-Feb_2009)
EnsemblPUS10 - 2p16.1 [CytoView hg19]  PUS10 - 2p16.1 [CytoView hg38]
Mapping of homologs : NCBIPUS10 [Mapview hg19]  PUS10 [Mapview hg38]
OMIM612787   
Gene and transcription
Genbank (Entrez)AA878516 AK056874 AK291729 AL832208 AW503429
RefSeq transcript (Entrez)NM_001322123 NM_001322124 NM_001322127 NM_144709
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PUS10
Cluster EST : UnigeneHs.368348 [ NCBI ]
CGAP (NCI)Hs.368348
Gene ExpressionPUS10 [ NCBI-GEO ]   PUS10 [ EBI - ARRAY_EXPRESS ]   PUS10 [ SEEK ]   PUS10 [ MEM ]
Gene Expression Viewer (FireBrowse)PUS10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)150962
GTEX Portal (Tissue expression)PUS10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ3MIT2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ3MIT2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ3MIT2
Splice isoforms : SwissVarQ3MIT2
Catalytic activity : Enzyme5.4.99.- [ Enzyme-Expasy ]   5.4.99.-5.4.99.- [ IntEnz-EBI ]   5.4.99.- [ BRENDA ]   5.4.99.- [ KEGG ]   
PhosPhoSitePlusQ3MIT2
Domains : Interpro (EBI)PsdUridine_synth_cat_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PUS10
DMDM Disease mutations150962
Blocks (Seattle)PUS10
PDB (SRS)2V9K   
PDB (PDBSum)2V9K   
PDB (IMB)2V9K   
PDB (RSDB)2V9K   
Structural Biology KnowledgeBase2V9K   
SCOP (Structural Classification of Proteins)2V9K   
CATH (Classification of proteins structures)2V9K   
SuperfamilyQ3MIT2
Peptide AtlasQ3MIT2
HPRD08126
IPIIPI00065521   IPI00893669   IPI00917865   
Protein Interaction databases
DIP (DOE-UCLA)Q3MIT2
IntAct (EBI)Q3MIT2
BioGRIDPUS10
STRING (EMBL)PUS10
ZODIACPUS10
Ontologies - Pathways
QuickGOQ3MIT2
Ontology : AmiGORNA binding  pseudouridine synthase activity  tRNA pseudouridine synthesis  
Ontology : EGO-EBIRNA binding  pseudouridine synthase activity  tRNA pseudouridine synthesis  
NDEx NetworkPUS10
Atlas of Cancer Signalling NetworkPUS10
Wikipedia pathwaysPUS10
Orthology - Evolution
OrthoDB150962
Phylogenetic Trees/Animal Genes : TreeFamPUS10
HOVERGENQ3MIT2
HOGENOMQ3MIT2
Homologs : HomoloGenePUS10
Homology/Alignments : Family Browser (UCSC)PUS10
Gene fusions - Rearrangements
Tumor Fusion PortalPUS10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPUS10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PUS10
dbVarPUS10
ClinVarPUS10
1000_GenomesPUS10 
Exome Variant ServerPUS10
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP150962
Genomic Variants (DGV)PUS10 [DGVbeta]
DECIPHERPUS10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPUS10 
Mutations
ICGC Data PortalPUS10 
TCGA Data PortalPUS10 
Broad Tumor PortalPUS10
OASIS PortalPUS10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPUS10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPUS10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PUS10
DgiDB (Drug Gene Interaction Database)PUS10
DoCM (Curated mutations)PUS10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PUS10 (select a term)
intoGenPUS10
Cancer3DPUS10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612787   
Orphanet
DisGeNETPUS10
MedgenPUS10
Genetic Testing Registry PUS10
NextProtQ3MIT2 [Medical]
TSGene150962
GENETestsPUS10
Target ValidationPUS10
Huge Navigator PUS10 [HugePedia]
snp3D : Map Gene to Disease150962
BioCentury BCIQPUS10
ClinGenPUS10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150962
Chemical/Pharm GKB GenePA162400393
Clinical trialPUS10
Miscellaneous
canSAR (ICR)PUS10 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePUS10
EVEXPUS10
GoPubMedPUS10
iHOPPUS10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:08:54 CET 2017

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