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PVR (poliovirus receptor)

Identity

Alias_namesPVS
Alias_symbol (synonym)CD155
HVED
Necl-5
NECL5
Tage4
Other aliasTAGE4
HGNC (Hugo) PVR
LocusID (NCBI) 5817
Atlas_Id 45814
Location 19q13.31  [Link to chromosome band 19q13]
Location_base_pair Starts at 44643798 and ends at 44666160 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PVR (19q13.31) / ERGIC1 (5q35.1)PVR (19q13.31) / PVR (19q13.31)PVR (19q13.31) / TANC1 (2q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PVR   9705
Cards
Entrez_Gene (NCBI)PVR  5817  poliovirus receptor
AliasesCD155; HVED; NECL5; Necl-5; 
PVS; TAGE4
GeneCards (Weizmann)PVR
Ensembl hg19 (Hinxton)ENSG00000073008 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000073008 [Gene_View]  chr19:44643798-44666160 [Contig_View]  PVR [Vega]
ICGC DataPortalENSG00000073008
TCGA cBioPortalPVR
AceView (NCBI)PVR
Genatlas (Paris)PVR
WikiGenes5817
SOURCE (Princeton)PVR
Genetics Home Reference (NIH)PVR
Genomic and cartography
GoldenPath hg38 (UCSC)PVR  -     chr19:44643798-44666160 +  19q13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PVR  -     19q13.31   [Description]    (hg19-Feb_2009)
EnsemblPVR - 19q13.31 [CytoView hg19]  PVR - 19q13.31 [CytoView hg38]
Mapping of homologs : NCBIPVR [Mapview hg19]  PVR [Mapview hg38]
OMIM173850   
Gene and transcription
Genbank (Entrez)AI374885 AK025949 AK094177 AK098812 AK290946
RefSeq transcript (Entrez)NM_001135768 NM_001135769 NM_001135770 NM_006505
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PVR
Cluster EST : UnigeneHs.171844 [ NCBI ]
CGAP (NCI)Hs.171844
Alternative Splicing GalleryENSG00000073008
Gene ExpressionPVR [ NCBI-GEO ]   PVR [ EBI - ARRAY_EXPRESS ]   PVR [ SEEK ]   PVR [ MEM ]
Gene Expression Viewer (FireBrowse)PVR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5817
GTEX Portal (Tissue expression)PVR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15151   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15151  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15151
Splice isoforms : SwissVarP15151
PhosPhoSitePlusP15151
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGv (SM00406)  
Conserved Domain (NCBI)PVR
DMDM Disease mutations5817
Blocks (Seattle)PVR
PDB (SRS)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
PDB (PDBSum)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
PDB (IMB)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
PDB (RSDB)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
Structural Biology KnowledgeBase1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
SCOP (Structural Classification of Proteins)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
CATH (Classification of proteins structures)1DGI    1NN8    3EPC    3EPD    3EPF    3J8F    3J9F    3UDW    3URO    4FQP   
SuperfamilyP15151
Human Protein AtlasENSG00000073008
Peptide AtlasP15151
HPRD01434
IPIIPI00299158   IPI00219425   IPI00219426   IPI00219427   IPI00892896   
Protein Interaction databases
DIP (DOE-UCLA)P15151
IntAct (EBI)P15151
FunCoupENSG00000073008
BioGRIDPVR
STRING (EMBL)PVR
ZODIACPVR
Ontologies - Pathways
QuickGOP15151
Ontology : AmiGOvirus receptor activity  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  receptor activity  receptor binding  protein binding  extracellular space  cytoplasm  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  focal adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  cell surface  integral component of membrane  adherens junction organization  susceptibility to natural killer cell mediated cytotoxicity  protein homodimerization activity  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  regulation of immune response  cell adhesion molecule binding  susceptibility to T cell mediated cytotoxicity  extracellular exosome  
Ontology : EGO-EBIvirus receptor activity  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  receptor activity  receptor binding  protein binding  extracellular space  cytoplasm  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  focal adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  cell surface  integral component of membrane  adherens junction organization  susceptibility to natural killer cell mediated cytotoxicity  protein homodimerization activity  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  regulation of immune response  cell adhesion molecule binding  susceptibility to T cell mediated cytotoxicity  extracellular exosome  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkPVR
Atlas of Cancer Signalling NetworkPVR
Wikipedia pathwaysPVR
Orthology - Evolution
OrthoDB5817
GeneTree (enSembl)ENSG00000073008
Phylogenetic Trees/Animal Genes : TreeFamPVR
HOVERGENP15151
HOGENOMP15151
Homologs : HomoloGenePVR
Homology/Alignments : Family Browser (UCSC)PVR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPVR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PVR
dbVarPVR
ClinVarPVR
1000_GenomesPVR 
Exome Variant ServerPVR
ExAC (Exome Aggregation Consortium)PVR (select the gene name)
Genetic variants : HAPMAP5817
Genomic Variants (DGV)PVR [DGVbeta]
DECIPHERPVR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPVR 
Mutations
ICGC Data PortalPVR 
TCGA Data PortalPVR 
Broad Tumor PortalPVR
OASIS PortalPVR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPVR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPVR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PVR
DgiDB (Drug Gene Interaction Database)PVR
DoCM (Curated mutations)PVR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PVR (select a term)
intoGenPVR
Cancer3DPVR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM173850   
Orphanet
MedgenPVR
Genetic Testing Registry PVR
NextProtP15151 [Medical]
TSGene5817
GENETestsPVR
Target ValidationPVR
Huge Navigator PVR [HugePedia]
snp3D : Map Gene to Disease5817
BioCentury BCIQPVR
ClinGenPVR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5817
Chemical/Pharm GKB GenePA34050
Clinical trialPVR
Miscellaneous
canSAR (ICR)PVR (select the gene name)
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePVR
EVEXPVR
GoPubMedPVR
iHOPPVR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:27:21 CEST 2017

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