PVRIG (PVR related immunoglobulin domain containing)

2018-02-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
C7orf15,CD112R

Other Information

Locus ID:

NCBI: 79037
MIM: 617012
HGNC: 32190
Ensembl: ENSG00000213413

Variants:

dbSNP: 79037
ClinVar: 79037
TCGA: ENSG00000213413
COSMIC: PVRIG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213413ENST00000317271Q6DKI7

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
267557052016Identification of CD112R as a novel checkpoint for human T cells.34
286234592017Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions.29
306590542019PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function.8

Citation

Dessen P

PVRIG (PVR related immunoglobulin domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57344/pvrig