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PVT1 (Pvt1 oncogene)

Identity

Alias (NCBI)LINC00079
MIR1204HG
NCRNA00079
onco-lncRNA-100
HGNC (Hugo) PVT1
HGNC Alias symbNCRNA00079
LINC00079
onco-lncRNA-100
MIR1204HG
HGNC Alias namenon-protein coding RNA 79
 long intergenic non-protein coding RNA 79
 MIR1204, MIR1205, MIR1206 and MIR1207 host gene
HGNC Previous namepvt-1 (murine) oncogene homolog, MYC activator
 Pvt1 oncogene homolog (mouse)
 Pvt1 oncogene (non-protein coding)
LocusID (NCBI) 5820
Atlas_Id 137
Location 8q24.21  [Link to chromosome band 8q24]
Location_base_pair Starts at 127794533 and ends at 128101253 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKT3 (1q43) / PVT1 (8q24.21)APIP (11p13) / PVT1 (8q24.21)CLPTM1L (5p15.33) / PVT1 (8q24.21)
EXOC4 (7q33) / PVT1 (8q24.21)GSDMC (8q24.21) / PVT1 (8q24.21)IGK (14q32.33) / PVT1 (8q24.21)
IGL (22q11.22) / PVT1 (8q24.21)IGLV3-10 () / PVT1 (8q24.21)MIR1204 (8q24.21) / PVT1 (8q24.21)
NARS (18q21.31) / PVT1 (8q24.21)PVT1 (8q24.21) / ANXA2 (15q22.2)PVT1 (8q24.21) / ARHGEF3 (3p14.3)
PVT1 (8q24.21) / ASAP1 (8q24.21)PVT1 (8q24.21) / ATE1 (10q26.13)PVT1 (8q24.21) / CCNB1IP1 (14q11.2)
PVT1 (8q24.21) / CHD7 (8q12.2)PVT1 (8q24.21) / CLVS1 (8q12.3)PVT1 (8q24.21) / COL6A1 (21q22.3)
PVT1 (8q24.21) / EYA1 (8q13.3)PVT1 (8q24.21) / LY6H (8q24.3)PVT1 (8q24.21) / MYC (8q24.21)
PVT1 (8q24.21) / MYH7 (14q11.2)PVT1 (8q24.21) / NBEA (13q13.3)PVT1 (8q24.21) / NDRG1 (8q24.22)
PVT1 (8q24.21) / NOL4 (18q12.1)PVT1 (8q24.21) / NSMCE2 (8q24.13)PVT1 (8q24.21) / PDHX (11p13)
PVT1 (8q24.21) / PLPP4 (10q26.12)PVT1 (8q24.21) / PVT1 (8q24.21)PVT1 (8q24.21) / SCCPDH (1q44)
PVT1 (8q24.21) / SLC7A7 (14q11.2)PVT1 (8q24.21) / SMARCA2 (9p24.3)PVT1 (8q24.21) / WWOX (16q23.1)
PVT1 (8q24.21) / ZCCHC7 (9p13.2)PVT1 (8q24.21) / abParts ()RFTN1 (3p25.1) / PVT1 (8q24.21)
RNF44 (5q35.2) / PVT1 (8q24.21)SAMD12 (8q24.12) / PVT1 (8q24.21)TRA () / PVT1 (8q24.21)
TRD () / PVT1 (8q24.21)UGCG (9q31.3) / PVT1 (8q24.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 10 ]
  t(3;8)(q26;q24) PVT1/MECOM
t(6;8)(p21;q24) MYC/SUPT3H
t(2;8)(p11;q24) IGK/PVT1
t(3;8)(p24;q24) RFTN1/PVT1
t(8;8)(q24;q24) PVT1/ASAP1
t(8;8)(q24;q24) PVT1/NSMCE2
t(8;9)(q24;p13) PVT1/ZCCHC7
t(8;9)(q24;q31) UGCG/PVT1
t(8;13)(q24;q13) PVT1/NBEA
t(8;14)(q24;q11) TRD/PVT1


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 22 ]
  Lung: Translocations in Small Cell Carcinoma
inv(8)(q24q24) PVT1/ZC3H3
t(1;8)(q44;q24) AKT3/PVT1
t(3;8)(p14;q24) PVT1/ARHGEF3
t(5;8)(p15;q24) CLPTM1L/PVT1
t(8;8)(q12;q24) PVT1/CHD7
t(8;8)(q12;q24) PVT1/CLVS1
t(8;8)(q13;q24) PVT1/EYA1
GSDMC/PVT1 (8q24)
PVT1/LINC00964 (8q24)
PVT1/MYC (8q24)
PVT1/MYC (8q24)
PVT1/MYC (8q24)
PVT1/NDRG1 (8q24)
PVT1/LY6H (8q24)
t(8;10)(q24;q26) PVT1/ATE1
t(8;11)(q24;p13) APIP/PVT1
t(8;11)(q24;p13) PVT1/PDHX
t(8;14)(q24;q11) PVT1/CCNB1IP1
t(8;14)(q24;q11) PVT1/MYH7
t(8;14)(q24;q11) PVT1/SLC7A7
t(8;18)(q24;q12) PVT1/NOL4


External links

Nomenclature
HGNC (Hugo)PVT1   9709
Cards
Entrez_Gene (NCBI)PVT1  5820  Pvt1 oncogene
AliasesLINC00079; MIR1204HG; NCRNA00079; onco-lncRNA-100
GeneCards (Weizmann)PVT1
Ensembl hg19 (Hinxton)ENSG00000249859 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000249859 [Gene_View]  ENSG00000249859 [Sequence]  chr8:127794533-128101253 [Contig_View]  PVT1 [Vega]
ICGC DataPortalENSG00000249859
TCGA cBioPortalPVT1
AceView (NCBI)PVT1
Genatlas (Paris)PVT1
WikiGenes5820
SOURCE (Princeton)PVT1
Genetics Home Reference (NIH)PVT1
Genomic and cartography
GoldenPath hg38 (UCSC)PVT1  -     chr8:127794533-128101253 +  8q24.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PVT1  -     8q24.21   [Description]    (hg19-Feb_2009)
GoldenPathPVT1 - 8q24.21 [CytoView hg19]  PVT1 - 8q24.21 [CytoView hg38]
ImmunoBaseENSG00000249859
genome Data Viewer NCBIPVT1 [Mapview hg19]  
OMIM165140   
Gene and transcription
Genbank (Entrez)AK128687 AK129745 BC033263 BC041065 BM821521
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PVT1
Alternative Splicing GalleryENSG00000249859
Gene ExpressionPVT1 [ NCBI-GEO ]   PVT1 [ EBI - ARRAY_EXPRESS ]   PVT1 [ SEEK ]   PVT1 [ MEM ]
Gene Expression Viewer (FireBrowse)PVT1 [ Firebrowse - Broad ]
GenevisibleExpression of PVT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5820
GTEX Portal (Tissue expression)PVT1
Human Protein AtlasENSG00000249859-PVT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PVT1
DMDM Disease mutations5820
Blocks (Seattle)PVT1
Human Protein Atlas [tissue]ENSG00000249859-PVT1 [tissue]
IPIIPI00796092   
Protein Interaction databases
FunCoupENSG00000249859
BioGRIDPVT1
STRING (EMBL)PVT1
ZODIACPVT1
Ontologies - Pathways
Huge Navigator PVT1 [HugePedia]
snp3D : Map Gene to Disease5820
BioCentury BCIQPVT1
ClinGenPVT1
Clinical trials, drugs, therapy
Protein Interactions : CTD5820
Pharm GKB GenePA34053
Clinical trialPVT1
Miscellaneous
canSAR (ICR)PVT1 (select the gene name)
HarmonizomePVT1
DataMed IndexPVT1
Probes
Litterature
PubMed166 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePVT1
EVEXPVT1
GoPubMedPVT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:29:01 CEST 2020

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