Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PVT1 (Pvt1 oncogene)


Alias_namespvt-1 (murine) oncogene homolog, MYC activator
Pvt1 oncogene homolog (mouse)
Pvt1 oncogene (non-protein coding)
Alias_symbol (synonym)NCRNA00079
Other alias
HGNC (Hugo) PVT1
LocusID (NCBI) 5820
Atlas_Id 137
Location 8q24.21  [Link to chromosome band 8q24]
Location_base_pair Starts at 127794533 and ends at 128101253 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKT3 (1q43) / PVT1 (8q24.21)APIP (11p13) / PVT1 (8q24.21)CLPTM1L (5p15.33) / PVT1 (8q24.21)
EXOC4 (7q33) / PVT1 (8q24.21)GSDMC (8q24.21) / PVT1 (8q24.21)IGK (14q32.33) / PVT1 (8q24.21)
IGL (22q11.22) / PVT1 (8q24.21)IGLV3-10 () / PVT1 (8q24.21)MIR1204 (8q24.21) / PVT1 (8q24.21)
NARS (18q21.31) / PVT1 (8q24.21)PVT1 (8q24.21) / ANXA2 (15q22.2)PVT1 (8q24.21) / ARHGEF3 (3p14.3)
PVT1 (8q24.21) / ASAP1 (8q24.21)PVT1 (8q24.21) / ATE1 (10q26.13)PVT1 (8q24.21) / CCNB1IP1 (14q11.2)
PVT1 (8q24.21) / CHD7 (8q12.2)PVT1 (8q24.21) / CLVS1 (8q12.3)PVT1 (8q24.21) / COL6A1 (21q22.3)
PVT1 (8q24.21) / EYA1 (8q13.3)PVT1 (8q24.21) / LY6H (8q24.3)PVT1 (8q24.21) / MYC (8q24.21)
PVT1 (8q24.21) / MYH7 (14q11.2)PVT1 (8q24.21) / NBEA (13q13.3)PVT1 (8q24.21) / NDRG1 (8q24.22)
PVT1 (8q24.21) / NOL4 (18q12.1)PVT1 (8q24.21) / NSMCE2 (8q24.13)PVT1 (8q24.21) / PDHX (11p13)
PVT1 (8q24.21) / PLPP4 (10q26.12)PVT1 (8q24.21) / PVT1 (8q24.21)PVT1 (8q24.21) / SCCPDH (1q44)
PVT1 (8q24.21) / SLC7A7 (14q11.2)PVT1 (8q24.21) / SMARCA2 (9p24.3)PVT1 (8q24.21) / WWOX (16q23.1)
PVT1 (8q24.21) / ZCCHC7 (9p13.2)PVT1 (8q24.21) / abParts ()RFTN1 (3p25.1) / PVT1 (8q24.21)
RNF44 (5q35.2) / PVT1 (8q24.21)SAMD12 (8q24.12) / PVT1 (8q24.21)TRA () / PVT1 (8q24.21)
TRD () / PVT1 (8q24.21)UGCG (9q31.3) / PVT1 (8q24.21)


Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 10 ]
  t(3;8)(q26;q24) PVT1/MECOM
t(2;8)(p11;q24) IGK/PVT1
t(3;8)(p24;q24) RFTN1/PVT1
t(8;8)(q24;q24) PVT1/ASAP1
t(8;8)(q24;q24) PVT1/NSMCE2
t(8;9)(q24;p13) PVT1/ZCCHC7
t(8;9)(q24;q31) UGCG/PVT1
t(8;13)(q24;q13) PVT1/NBEA
t(8;14)(q24;q11) TRD/PVT1
t(8;22)(q24;q11) IGL/PVT1

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 22 ]
  Lung: Translocations in Small Cell Carcinoma
inv(8)(q24q24) PVT1/ZC3H3
t(1;8)(q44;q24) AKT3/PVT1
t(3;8)(p14;q24) PVT1/ARHGEF3
t(5;8)(p15;q24) CLPTM1L/PVT1
t(8;8)(q12;q24) PVT1/CHD7
t(8;8)(q12;q24) PVT1/CLVS1
t(8;8)(q13;q24) PVT1/EYA1
GSDMC/PVT1 (8q24)
PVT1/LINC00964 (8q24)
PVT1/MYC (8q24)
PVT1/MYC (8q24)
PVT1/MYC (8q24)
PVT1/NDRG1 (8q24)
PVT1/LY6H (8q24)
t(8;10)(q24;q26) PVT1/ATE1
t(8;11)(q24;p13) APIP/PVT1
t(8;11)(q24;p13) PVT1/PDHX
t(8;14)(q24;q11) PVT1/CCNB1IP1
t(8;14)(q24;q11) PVT1/MYH7
t(8;14)(q24;q11) PVT1/SLC7A7
t(8;18)(q24;q12) PVT1/NOL4

External links

HGNC (Hugo)PVT1   9709
Entrez_Gene (NCBI)PVT1  5820  Pvt1 oncogene
AliasesLINC00079; MIR1204HG; NCRNA00079; onco-lncRNA-100
GeneCards (Weizmann)PVT1
Ensembl hg19 (Hinxton)ENSG00000249859 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000249859 [Gene_View]  ENSG00000249859 [Sequence]  chr8:127794533-128101253 [Contig_View]  PVT1 [Vega]
ICGC DataPortalENSG00000249859
TCGA cBioPortalPVT1
AceView (NCBI)PVT1
Genatlas (Paris)PVT1
SOURCE (Princeton)PVT1
Genetics Home Reference (NIH)PVT1
Genomic and cartography
GoldenPath hg38 (UCSC)PVT1  -     chr8:127794533-128101253 +  8q24.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PVT1  -     8q24.21   [Description]    (hg19-Feb_2009)
GoldenPathPVT1 - 8q24.21 [CytoView hg19]  PVT1 - 8q24.21 [CytoView hg38]
Mapping of homologs : NCBIPVT1 [Mapview hg19]  PVT1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK128687 AK129745 BC033263 BC041065 BM821521
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PVT1
Cluster EST : UnigeneHs.675281 [ NCBI ]
CGAP (NCI)Hs.675281
Alternative Splicing GalleryENSG00000249859
Gene ExpressionPVT1 [ NCBI-GEO ]   PVT1 [ EBI - ARRAY_EXPRESS ]   PVT1 [ SEEK ]   PVT1 [ MEM ]
Gene Expression Viewer (FireBrowse)PVT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)5820
GTEX Portal (Tissue expression)PVT1
Human Protein AtlasENSG00000249859-PVT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PVT1
DMDM Disease mutations5820
Blocks (Seattle)PVT1
Human Protein Atlas [tissue]ENSG00000249859-PVT1 [tissue]
Protein Interaction databases
Ontologies - Pathways
Huge Navigator PVT1 [HugePedia]
snp3D : Map Gene to Disease5820
BioCentury BCIQPVT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5820
Chemical/Pharm GKB GenePA34053
Clinical trialPVT1
canSAR (ICR)PVT1 (select the gene name)
DataMed IndexPVT1
PubMed136 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:03:28 CET 2019

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