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PVT1 (Pvt1 oncogene)

Identity

Alias (NCBI)LINC00079
MIR1204HG
NCRNA00079
onco-lncRNA-100
HGNC (Hugo) PVT1
HGNC Alias symbNCRNA00079
LINC00079
onco-lncRNA-100
MIR1204HG
HGNC Alias namenon-protein coding RNA 79
 long intergenic non-protein coding RNA 79
 MIR1204, MIR1205, MIR1206 and MIR1207 host gene
 plasmacytoma variant translocation 1
HGNC Previous namepvt-1 (murine) oncogene homolog, MYC activator
 Pvt1 oncogene homolog (mouse)
 Pvt1 oncogene (non-protein coding)
LocusID (NCBI) 5820
Atlas_Id 137
Location 8q24.21  [Link to chromosome band 8q24]
Location_base_pair Starts at 127794533 and ends at 128101253 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKT3 (1q43) / PVT1 (8q24.21)APIP (11p13) / PVT1 (8q24.21)CLPTM1L (5p15.33) / PVT1 (8q24.21)
EXOC4 (7q33) / PVT1 (8q24.21)GSDMC (8q24.21) / PVT1 (8q24.21)IGK (14q32.33) / PVT1 (8q24.21)
IGL (22q11.22) / PVT1 (8q24.21)IGLV3-10 () / PVT1 (8q24.21)MIR1204 (8q24.21) / PVT1 (8q24.21)
NARS (18q21.31) / PVT1 (8q24.21)PVT1 (8q24.21) / ANXA2 (15q22.2)PVT1 (8q24.21) / ARHGEF3 (3p14.3)
PVT1 (8q24.21) / ASAP1 (8q24.21)PVT1 (8q24.21) / ATE1 (10q26.13)PVT1 (8q24.21) / CCNB1IP1 (14q11.2)
PVT1 (8q24.21) / CHD7 (8q12.2)PVT1 (8q24.21) / CLVS1 (8q12.3)PVT1 (8q24.21) / COL6A1 (21q22.3)
PVT1 (8q24.21) / EYA1 (8q13.3)PVT1 (8q24.21) / LY6H (8q24.3)PVT1 (8q24.21) / MYC (8q24.21)
PVT1 (8q24.21) / MYH7 (14q11.2)PVT1 (8q24.21) / NBEA (13q13.3)PVT1 (8q24.21) / NDRG1 (8q24.22)
PVT1 (8q24.21) / NOL4 (18q12.1)PVT1 (8q24.21) / NSMCE2 (8q24.13)PVT1 (8q24.21) / PDHX (11p13)
PVT1 (8q24.21) / PLPP4 (10q26.12)PVT1 (8q24.21) / PVT1 (8q24.21)PVT1 (8q24.21) / SCCPDH (1q44)
PVT1 (8q24.21) / SLC7A7 (14q11.2)PVT1 (8q24.21) / SMARCA2 (9p24.3)PVT1 (8q24.21) / WWOX (16q23.1)
PVT1 (8q24.21) / ZCCHC7 (9p13.2)PVT1 (8q24.21) / abParts ()RFTN1 (3p25.1) / PVT1 (8q24.21)
RNF44 (5q35.2) / PVT1 (8q24.21)SAMD12 (8q24.12) / PVT1 (8q24.21)TRA () / PVT1 (8q24.21)
TRD () / PVT1 (8q24.21)UGCG (9q31.3) / PVT1 (8q24.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 10 ]
  t(3;8)(q26;q24) PVT1/MECOM
t(6;8)(p21;q24) MYC/SUPT3H
t(2;8)(p11;q24) IGK/PVT1
t(3;8)(p24;q24) RFTN1/PVT1
t(8;8)(q24;q24) PVT1/ASAP1
t(8;8)(q24;q24) PVT1/NSMCE2
t(8;9)(q24;p13) PVT1/ZCCHC7
t(8;9)(q24;q31) UGCG/PVT1
t(8;13)(q24;q13) PVT1/NBEA
t(8;14)(q24;q11) TRD/PVT1


External links

Nomenclature
HGNC (Hugo)PVT1   9709
Cards
Entrez_Gene (NCBI)PVT1    Pvt1 oncogene
AliasesLINC00079; MIR1204HG; NCRNA00079; onco-lncRNA-100
GeneCards (Weizmann)PVT1
Ensembl hg19 (Hinxton)ENSG00000249859 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000249859 [Gene_View]  ENSG00000249859 [Sequence]  chr8:127794533-128101253 [Contig_View]  PVT1 [Vega]
ICGC DataPortalENSG00000249859
TCGA cBioPortalPVT1
AceView (NCBI)PVT1
Genatlas (Paris)PVT1
SOURCE (Princeton)PVT1
Genetics Home Reference (NIH)PVT1
Genomic and cartography
GoldenPath hg38 (UCSC)PVT1  -     chr8:127794533-128101253 +  8q24.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PVT1  -     8q24.21   [Description]    (hg19-Feb_2009)
GoldenPathPVT1 - 8q24.21 [CytoView hg19]  PVT1 - 8q24.21 [CytoView hg38]
ImmunoBaseENSG00000249859
Genome Data Viewer NCBIPVT1 [Mapview hg19]  
OMIM165140   
Gene and transcription
Genbank (Entrez)AK128687 AK129745 BC033263 BC041065 BM821521
RefSeq transcript (Entrez)
Consensus coding sequences : CCDS (NCBI)PVT1
Gene ExpressionPVT1 [ NCBI-GEO ]   PVT1 [ EBI - ARRAY_EXPRESS ]   PVT1 [ SEEK ]   PVT1 [ MEM ]
Gene Expression Viewer (FireBrowse)PVT1 [ Firebrowse - Broad ]
GenevisibleExpression of PVT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5820
GTEX Portal (Tissue expression)PVT1
Human Protein AtlasENSG00000249859-PVT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PVT1
Human Protein Atlas [tissue]ENSG00000249859-PVT1 [tissue]
Protein Interaction databases
BioGRIDPVT1
STRING (EMBL)PVT1
ZODIACPVT1
Ontologies - Pathways
Litterature
PubMed200 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPVT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:27:37 CEST 2021

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