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PWP1 (PWP1 homolog, endonuclein)

Identity

Alias_namesPWP1 homolog (S. cerevisiae)
Alias_symbol (synonym)IEF-SSP-9502
Other alias
HGNC (Hugo) PWP1
LocusID (NCBI) 11137
Atlas_Id 72413
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 107686042 and ends at 107713162 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DCAF8 (1q23.2) / PWP1 (12q23.3)DHX9 (1q25.3) / PWP1 (12q23.3)GSK3A (19q13.2) / PWP1 (12q23.3)
SRGAP1 (12q14.2) / PWP1 (12q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PWP1   17015
Cards
Entrez_Gene (NCBI)PWP1  11137  PWP1 homolog, endonuclein
AliasesIEF-SSP-9502
GeneCards (Weizmann)PWP1
Ensembl hg19 (Hinxton)ENSG00000136045 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136045 [Gene_View]  chr12:107686042-107713162 [Contig_View]  PWP1 [Vega]
ICGC DataPortalENSG00000136045
TCGA cBioPortalPWP1
AceView (NCBI)PWP1
Genatlas (Paris)PWP1
WikiGenes11137
SOURCE (Princeton)PWP1
Genetics Home Reference (NIH)PWP1
Genomic and cartography
GoldenPath hg38 (UCSC)PWP1  -     chr12:107686042-107713162 +  12q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PWP1  -     12q23.3   [Description]    (hg19-Feb_2009)
EnsemblPWP1 - 12q23.3 [CytoView hg19]  PWP1 - 12q23.3 [CytoView hg38]
Mapping of homologs : NCBIPWP1 [Mapview hg19]  PWP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK223162 AK290681 AK296252 AK297961 BC000067
RefSeq transcript (Entrez)NM_001317962 NM_001317963 NM_007062
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PWP1
Cluster EST : UnigeneHs.506652 [ NCBI ]
CGAP (NCI)Hs.506652
Alternative Splicing GalleryENSG00000136045
Gene ExpressionPWP1 [ NCBI-GEO ]   PWP1 [ EBI - ARRAY_EXPRESS ]   PWP1 [ SEEK ]   PWP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PWP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11137
GTEX Portal (Tissue expression)PWP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13610   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13610  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13610
Splice isoforms : SwissVarQ13610
PhosPhoSitePlusQ13610
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)PWP1
DMDM Disease mutations11137
Blocks (Seattle)PWP1
SuperfamilyQ13610
Human Protein AtlasENSG00000136045
Peptide AtlasQ13610
HPRD11464
IPIIPI00014298   IPI01009768   IPI00789042   IPI01012342   IPI01009157   IPI01022504   IPI01020887   IPI00385054   
Protein Interaction databases
DIP (DOE-UCLA)Q13610
IntAct (EBI)Q13610
FunCoupENSG00000136045
BioGRIDPWP1
STRING (EMBL)PWP1
ZODIACPWP1
Ontologies - Pathways
QuickGOQ13610
Ontology : AmiGOnucleus  nucleolus  Golgi apparatus  transcription, DNA-templated  histone H4-K20 trimethylation  H4K20me3 modified histone binding  positive regulation of stem cell differentiation  
Ontology : EGO-EBInucleus  nucleolus  Golgi apparatus  transcription, DNA-templated  histone H4-K20 trimethylation  H4K20me3 modified histone binding  positive regulation of stem cell differentiation  
NDEx NetworkPWP1
Atlas of Cancer Signalling NetworkPWP1
Wikipedia pathwaysPWP1
Orthology - Evolution
OrthoDB11137
GeneTree (enSembl)ENSG00000136045
Phylogenetic Trees/Animal Genes : TreeFamPWP1
HOVERGENQ13610
HOGENOMQ13610
Homologs : HomoloGenePWP1
Homology/Alignments : Family Browser (UCSC)PWP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPWP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PWP1
dbVarPWP1
ClinVarPWP1
1000_GenomesPWP1 
Exome Variant ServerPWP1
ExAC (Exome Aggregation Consortium)PWP1 (select the gene name)
Genetic variants : HAPMAP11137
Genomic Variants (DGV)PWP1 [DGVbeta]
DECIPHERPWP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPWP1 
Mutations
ICGC Data PortalPWP1 
TCGA Data PortalPWP1 
Broad Tumor PortalPWP1
OASIS PortalPWP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPWP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPWP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PWP1
DgiDB (Drug Gene Interaction Database)PWP1
DoCM (Curated mutations)PWP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PWP1 (select a term)
intoGenPWP1
Cancer3DPWP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPWP1
Genetic Testing Registry PWP1
NextProtQ13610 [Medical]
TSGene11137
GENETestsPWP1
Target ValidationPWP1
Huge Navigator PWP1 [HugePedia]
snp3D : Map Gene to Disease11137
BioCentury BCIQPWP1
ClinGenPWP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11137
Chemical/Pharm GKB GenePA142671112
Clinical trialPWP1
Miscellaneous
canSAR (ICR)PWP1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePWP1
EVEXPWP1
GoPubMedPWP1
iHOPPWP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:37:57 CEST 2017

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