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PWP2 (PWP2 periodic tryptophan protein homolog (yeast))

Identity

Alias_namesPWP2H
PWP2 (periodic tryptophan protein, yeast) homolog
Alias_symbol (synonym)EHOC-17
UTP1
Other alias
HGNC (Hugo) PWP2
LocusID (NCBI) 5822
Atlas_Id 72414
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 45527208 and ends at 45551063 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PWP2 (21q22.3) / IFT140 (16p13.3)PWP2 (21q22.3) / SFSWAP (12q24.33)TCF3 (19p13.3) / PWP2 (21q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PWP2   9711
Cards
Entrez_Gene (NCBI)PWP2  5822  PWP2 periodic tryptophan protein homolog (yeast)
AliasesEHOC-17; PWP2H; UTP1
GeneCards (Weizmann)PWP2
Ensembl hg19 (Hinxton)ENSG00000241945 [Gene_View]  chr21:45527208-45551063 [Contig_View]  PWP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000241945 [Gene_View]  chr21:45527208-45551063 [Contig_View]  PWP2 [Vega]
ICGC DataPortalENSG00000241945
TCGA cBioPortalPWP2
AceView (NCBI)PWP2
Genatlas (Paris)PWP2
WikiGenes5822
SOURCE (Princeton)PWP2
Genetics Home Reference (NIH)PWP2
Genomic and cartography
GoldenPath hg19 (UCSC)PWP2  -     chr21:45527208-45551063 +  21q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PWP2  -     21q22.3   [Description]    (hg38-Dec_2013)
EnsemblPWP2 - 21q22.3 [CytoView hg19]  PWP2 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBIPWP2 [Mapview hg19]  PWP2 [Mapview hg38]
OMIM601475   
Gene and transcription
Genbank (Entrez)AB209438 AI968015 AK314184 BC013309 BC014988
RefSeq transcript (Entrez)NM_005049
RefSeq genomic (Entrez)NC_000021 NT_011512
Consensus coding sequences : CCDS (NCBI)PWP2
Cluster EST : UnigeneHs.449076 [ NCBI ]
CGAP (NCI)Hs.449076
Alternative Splicing GalleryENSG00000241945
Gene ExpressionPWP2 [ NCBI-GEO ]   PWP2 [ EBI - ARRAY_EXPRESS ]   PWP2 [ SEEK ]   PWP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PWP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5822
GTEX Portal (Tissue expression)PWP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15269   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15269  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15269
Splice isoforms : SwissVarQ15269
PhosPhoSitePlusQ15269
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    PWP2    Quinonprotein_ADH-like_supfam    SSU_processome_Utp12    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)Utp12 (PF04003)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam04003    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)PWP2
DMDM Disease mutations5822
Blocks (Seattle)PWP2
SuperfamilyQ15269
Human Protein AtlasENSG00000241945
Peptide AtlasQ15269
HPRD03279
IPIIPI00300078   IPI00556044   IPI00797937   
Protein Interaction databases
DIP (DOE-UCLA)Q15269
IntAct (EBI)Q15269
FunCoupENSG00000241945
BioGRIDPWP2
STRING (EMBL)PWP2
ZODIACPWP2
Ontologies - Pathways
QuickGOQ15269
Ontology : AmiGOribosomal small subunit assembly  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  nucleolus  cytoplasm  snoRNA binding  small-subunit processome  Pwp2p-containing subcomplex of 90S preribosome  poly(A) RNA binding  
Ontology : EGO-EBIribosomal small subunit assembly  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  nucleolus  cytoplasm  snoRNA binding  small-subunit processome  Pwp2p-containing subcomplex of 90S preribosome  poly(A) RNA binding  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkPWP2
Atlas of Cancer Signalling NetworkPWP2
Wikipedia pathwaysPWP2
Orthology - Evolution
OrthoDB5822
GeneTree (enSembl)ENSG00000241945
Phylogenetic Trees/Animal Genes : TreeFamPWP2
HOVERGENQ15269
HOGENOMQ15269
Homologs : HomoloGenePWP2
Homology/Alignments : Family Browser (UCSC)PWP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPWP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PWP2
dbVarPWP2
ClinVarPWP2
1000_GenomesPWP2 
Exome Variant ServerPWP2
ExAC (Exome Aggregation Consortium)PWP2 (select the gene name)
Genetic variants : HAPMAP5822
Genomic Variants (DGV)PWP2 [DGVbeta]
DECIPHER (Syndromes)21:45527208-45551063  ENSG00000241945
CONAN: Copy Number AnalysisPWP2 
Mutations
ICGC Data PortalPWP2 
TCGA Data PortalPWP2 
Broad Tumor PortalPWP2
OASIS PortalPWP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPWP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPWP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PWP2
DgiDB (Drug Gene Interaction Database)PWP2
DoCM (Curated mutations)PWP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PWP2 (select a term)
intoGenPWP2
Cancer3DPWP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601475   
Orphanet
MedgenPWP2
Genetic Testing Registry PWP2
NextProtQ15269 [Medical]
TSGene5822
GENETestsPWP2
Huge Navigator PWP2 [HugePedia]
snp3D : Map Gene to Disease5822
BioCentury BCIQPWP2
ClinGenPWP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5822
Chemical/Pharm GKB GenePA162400451
Clinical trialPWP2
Miscellaneous
canSAR (ICR)PWP2 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePWP2
EVEXPWP2
GoPubMedPWP2
iHOPPWP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:40:17 CET 2017

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