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PXDC1 (PX domain containing 1)

Identity

Alias_namesC6orf145
chromosome 6 open reading frame 145
Other alias
HGNC (Hugo) PXDC1
LocusID (NCBI) 221749
Atlas_Id 72418
Location 6p25.2  [Link to chromosome band 6p25]
Location_base_pair Starts at 3722602 and ends at 3752012 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RAB27B (18q21.2) / PXDC1 (6p25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;18)(p25;q21) RAB27B/PXDC1


External links

Nomenclature
HGNC (Hugo)PXDC1   21361
Cards
Entrez_Gene (NCBI)PXDC1  221749  PX domain containing 1
AliasesC6orf145
GeneCards (Weizmann)PXDC1
Ensembl hg19 (Hinxton)ENSG00000168994 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168994 [Gene_View]  ENSG00000168994 [Sequence]  chr6:3722602-3752012 [Contig_View]  PXDC1 [Vega]
ICGC DataPortalENSG00000168994
TCGA cBioPortalPXDC1
AceView (NCBI)PXDC1
Genatlas (Paris)PXDC1
WikiGenes221749
SOURCE (Princeton)PXDC1
Genetics Home Reference (NIH)PXDC1
Genomic and cartography
GoldenPath hg38 (UCSC)PXDC1  -     chr6:3722602-3752012 -  6p25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PXDC1  -     6p25.2   [Description]    (hg19-Feb_2009)
EnsemblPXDC1 - 6p25.2 [CytoView hg19]  PXDC1 - 6p25.2 [CytoView hg38]
Mapping of homologs : NCBIPXDC1 [Mapview hg19]  PXDC1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ420534 AK024828 AK289598 AL832792 BC045715
RefSeq transcript (Entrez)NM_183373
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PXDC1
Cluster EST : UnigeneHs.484500 [ NCBI ]
CGAP (NCI)Hs.484500
Alternative Splicing GalleryENSG00000168994
Gene ExpressionPXDC1 [ NCBI-GEO ]   PXDC1 [ EBI - ARRAY_EXPRESS ]   PXDC1 [ SEEK ]   PXDC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PXDC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221749
GTEX Portal (Tissue expression)PXDC1
Human Protein AtlasENSG00000168994-PXDC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TGL8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TGL8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TGL8
Splice isoforms : SwissVarQ5TGL8
PhosPhoSitePlusQ5TGL8
Domains : Interpro (EBI)Phox   
Domain families : Pfam (Sanger)PX (PF00787)   
Domain families : Pfam (NCBI)pfam00787   
Conserved Domain (NCBI)PXDC1
DMDM Disease mutations221749
Blocks (Seattle)PXDC1
SuperfamilyQ5TGL8
Human Protein Atlas [tissue]ENSG00000168994-PXDC1 [tissue]
Peptide AtlasQ5TGL8
HPRD12854
IPIIPI00373820   IPI00921084   IPI00644152   
Protein Interaction databases
DIP (DOE-UCLA)Q5TGL8
IntAct (EBI)Q5TGL8
FunCoupENSG00000168994
BioGRIDPXDC1
STRING (EMBL)PXDC1
ZODIACPXDC1
Ontologies - Pathways
QuickGOQ5TGL8
Ontology : AmiGOphosphatidylinositol binding  
Ontology : EGO-EBIphosphatidylinositol binding  
NDEx NetworkPXDC1
Atlas of Cancer Signalling NetworkPXDC1
Wikipedia pathwaysPXDC1
Orthology - Evolution
OrthoDB221749
GeneTree (enSembl)ENSG00000168994
Phylogenetic Trees/Animal Genes : TreeFamPXDC1
HOVERGENQ5TGL8
HOGENOMQ5TGL8
Homologs : HomoloGenePXDC1
Homology/Alignments : Family Browser (UCSC)PXDC1
Gene fusions - Rearrangements
Fusion : QuiverPXDC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPXDC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PXDC1
dbVarPXDC1
ClinVarPXDC1
1000_GenomesPXDC1 
Exome Variant ServerPXDC1
ExAC (Exome Aggregation Consortium)ENSG00000168994
GNOMAD BrowserENSG00000168994
Varsome BrowserPXDC1
Genetic variants : HAPMAP221749
Genomic Variants (DGV)PXDC1 [DGVbeta]
DECIPHERPXDC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPXDC1 
Mutations
ICGC Data PortalPXDC1 
TCGA Data PortalPXDC1 
Broad Tumor PortalPXDC1
OASIS PortalPXDC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPXDC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPXDC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PXDC1
DgiDB (Drug Gene Interaction Database)PXDC1
DoCM (Curated mutations)PXDC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PXDC1 (select a term)
intoGenPXDC1
Cancer3DPXDC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPXDC1
MedgenPXDC1
Genetic Testing Registry PXDC1
NextProtQ5TGL8 [Medical]
TSGene221749
GENETestsPXDC1
Target ValidationPXDC1
Huge Navigator PXDC1 [HugePedia]
snp3D : Map Gene to Disease221749
BioCentury BCIQPXDC1
ClinGenPXDC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221749
Chemical/Pharm GKB GenePA134944183
Clinical trialPXDC1
Miscellaneous
canSAR (ICR)PXDC1 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePXDC1
EVEXPXDC1
GoPubMedPXDC1
iHOPPXDC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 14:25:45 CEST 2018

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