Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PXDN (peroxidasin)

Identity

Alias (NCBI)ASGD7
COPOA
D2S448
D2S448E
MG50
PRG2
PXN
VPO
HGNC (Hugo) PXDN
HGNC Alias symbKIAA0230
PRG2
MG50
D2S448
D2S448E
PXN
HGNC Previous nameperoxidasin homolog (Drosophila)
LocusID (NCBI) 7837
Atlas_Id 40257
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 1631887 and ends at 1744515 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PXDN (2p25.3) / NEAT1 (11q13.1)PXDN (2p25.3) / PXDN (2p25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PXDN   14966
Cards
Entrez_Gene (NCBI)PXDN    peroxidasin
AliasesASGD7; COPOA; D2S448; D2S448E; 
MG50; PRG2; PXN; VPO
GeneCards (Weizmann)PXDN
Ensembl hg19 (Hinxton)ENSG00000130508 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130508 [Gene_View]  ENSG00000130508 [Sequence]  chr2:1631887-1744515 [Contig_View]  PXDN [Vega]
ICGC DataPortalENSG00000130508
TCGA cBioPortalPXDN
AceView (NCBI)PXDN
Genatlas (Paris)PXDN
SOURCE (Princeton)PXDN
Genetics Home Reference (NIH)PXDN
Genomic and cartography
GoldenPath hg38 (UCSC)PXDN  -     chr2:1631887-1744515 -  2p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PXDN  -     2p25.3   [Description]    (hg19-Feb_2009)
GoldenPathPXDN - 2p25.3 [CytoView hg19]  PXDN - 2p25.3 [CytoView hg38]
ImmunoBaseENSG00000130508
Genome Data Viewer NCBIPXDN [Mapview hg19]  
OMIM269400   605158   
Gene and transcription
Genbank (Entrez)AF200348 AK098167 BC009496 BC030834 BC041027
RefSeq transcript (Entrez)NM_012293
Consensus coding sequences : CCDS (NCBI)PXDN
Gene ExpressionPXDN [ NCBI-GEO ]   PXDN [ EBI - ARRAY_EXPRESS ]   PXDN [ SEEK ]   PXDN [ MEM ]
Gene Expression Viewer (FireBrowse)PXDN [ Firebrowse - Broad ]
GenevisibleExpression of PXDN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7837
GTEX Portal (Tissue expression)PXDN
Human Protein AtlasENSG00000130508-PXDN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92626   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92626  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92626
PhosPhoSitePlusQ92626
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)    PEROXIDASE_3 (PS50292)    VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Haem_peroxidase_animal    Haem_peroxidase_sf    Haem_peroxidase_sf_animal    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    Peroxidasin_peroxidase    Peroxidasin_vert    VWF_dom   
Domain families : Pfam (Sanger)An_peroxidase (PF03098)    I-set (PF07679)    LRR_8 (PF13855)    VWC (PF00093)   
Domain families : Pfam (NCBI)pfam03098    pfam07679    pfam13855    pfam00093   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  VWC (SM00214)  
Conserved Domain (NCBI)PXDN
SuperfamilyQ92626
AlphaFold pdb e-kbQ92626   
Human Protein Atlas [tissue]ENSG00000130508-PXDN [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q92626
IntAct (EBI)Q92626
BioGRIDPXDN
STRING (EMBL)PXDN
ZODIACPXDN
Ontologies - Pathways
QuickGOQ92626
Ontology : AmiGOnegative regulation of cytokine-mediated signaling pathway  peroxidase activity  peroxidase activity  interleukin-1 receptor antagonist activity  extracellular matrix structural constituent  extracellular matrix structural constituent  extracellular region  extracellular space  extracellular space  endoplasmic reticulum  immune response  response to oxidative stress  bromide peroxidase activity  heme binding  extracellular matrix organization  collagen fibril organization  collagen fibril organization  hydrogen peroxide catabolic process  metal ion binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  basement membrane assembly  cellular oxidant detoxification  
Ontology : EGO-EBInegative regulation of cytokine-mediated signaling pathway  peroxidase activity  peroxidase activity  interleukin-1 receptor antagonist activity  extracellular matrix structural constituent  extracellular matrix structural constituent  extracellular region  extracellular space  extracellular space  endoplasmic reticulum  immune response  response to oxidative stress  bromide peroxidase activity  heme binding  extracellular matrix organization  collagen fibril organization  collagen fibril organization  hydrogen peroxide catabolic process  metal ion binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  basement membrane assembly  cellular oxidant detoxification  
NDEx NetworkPXDN
Atlas of Cancer Signalling NetworkPXDN
Wikipedia pathwaysPXDN
Orthology - Evolution
OrthoDB7837
GeneTree (enSembl)ENSG00000130508
Phylogenetic Trees/Animal Genes : TreeFamPXDN
Homologs : HomoloGenePXDN
Homology/Alignments : Family Browser (UCSC)PXDN
Gene fusions - Rearrangements
Fusion : QuiverPXDN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPXDN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PXDN
dbVarPXDN
ClinVarPXDN
MonarchPXDN
1000_GenomesPXDN 
Exome Variant ServerPXDN
GNOMAD BrowserENSG00000130508
Varsome BrowserPXDN
ACMGPXDN variants
VarityQ92626
Genomic Variants (DGV)PXDN [DGVbeta]
DECIPHERPXDN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPXDN 
Mutations
ICGC Data PortalPXDN 
TCGA Data PortalPXDN 
Broad Tumor PortalPXDN
OASIS PortalPXDN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPXDN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPXDN
Mutations and Diseases : HGMDPXDN
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPXDN
DgiDB (Drug Gene Interaction Database)PXDN
DoCM (Curated mutations)PXDN
CIViC (Clinical Interpretations of Variants in Cancer)PXDN
Cancer3DPXDN
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM269400    605158   
Orphanet20730   
DisGeNETPXDN
MedgenPXDN
Genetic Testing Registry PXDN
NextProtQ92626 [Medical]
GENETestsPXDN
Target ValidationPXDN
Huge Navigator PXDN [HugePedia]
ClinGenPXDN
Clinical trials, drugs, therapy
MyCancerGenomePXDN
Protein Interactions : CTDPXDN
Pharm GKB GenePA128394535
PharosQ92626
Clinical trialPXDN
Miscellaneous
canSAR (ICR)PXDN
HarmonizomePXDN
DataMed IndexPXDN
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPXDN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:27:38 CEST 2021

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