Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PXDN (peroxidasin)

Identity

Alias_namesperoxidasin homolog (Drosophila)
Alias_symbol (synonym)KIAA0230
PRG2
MG50
D2S448
D2S448E
PXN
Other aliasCOPOA
VPO
HGNC (Hugo) PXDN
LocusID (NCBI) 7837
Atlas_Id 40257
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 1635659 and ends at 1748319 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PXDN (2p25.3) / NEAT1 (11q13.1)PXDN (2p25.3) / PXDN (2p25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PXDN   14966
Cards
Entrez_Gene (NCBI)PXDN  7837  peroxidasin
AliasesCOPOA; D2S448; D2S448E; MG50; 
PRG2; PXN; VPO
GeneCards (Weizmann)PXDN
Ensembl hg19 (Hinxton)ENSG00000130508 [Gene_View]  chr2:1635659-1748319 [Contig_View]  PXDN [Vega]
Ensembl hg38 (Hinxton)ENSG00000130508 [Gene_View]  chr2:1635659-1748319 [Contig_View]  PXDN [Vega]
ICGC DataPortalENSG00000130508
TCGA cBioPortalPXDN
AceView (NCBI)PXDN
Genatlas (Paris)PXDN
WikiGenes7837
SOURCE (Princeton)PXDN
Genetics Home Reference (NIH)PXDN
Genomic and cartography
GoldenPath hg19 (UCSC)PXDN  -     chr2:1635659-1748319 -  2p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PXDN  -     2p25.3   [Description]    (hg38-Dec_2013)
EnsemblPXDN - 2p25.3 [CytoView hg19]  PXDN - 2p25.3 [CytoView hg38]
Mapping of homologs : NCBIPXDN [Mapview hg19]  PXDN [Mapview hg38]
OMIM269400   605158   
Gene and transcription
Genbank (Entrez)AF200348 AK098167 BC009496 BC030834 BC041027
RefSeq transcript (Entrez)NM_012293
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_034221 NT_005334 NW_004929296
Consensus coding sequences : CCDS (NCBI)PXDN
Cluster EST : UnigeneHs.332197 [ NCBI ]
CGAP (NCI)Hs.332197
Alternative Splicing GalleryENSG00000130508
Gene ExpressionPXDN [ NCBI-GEO ]   PXDN [ EBI - ARRAY_EXPRESS ]   PXDN [ SEEK ]   PXDN [ MEM ]
Gene Expression Viewer (FireBrowse)PXDN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7837
GTEX Portal (Tissue expression)PXDN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92626   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92626  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92626
Splice isoforms : SwissVarQ92626
Catalytic activity : Enzyme1.11.1.7 [ Enzyme-Expasy ]   1.11.1.71.11.1.7 [ IntEnz-EBI ]   1.11.1.7 [ BRENDA ]   1.11.1.7 [ KEGG ]   
PhosPhoSitePlusQ92626
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)    PEROXIDASE_3 (PS50292)    VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Haem_peroxidase    Haem_peroxidase_animal    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT    VWF_dom   
Domain families : Pfam (Sanger)An_peroxidase (PF03098)    I-set (PF07679)    LRR_8 (PF13855)    VWC (PF00093)   
Domain families : Pfam (NCBI)pfam03098    pfam07679    pfam13855    pfam00093   
Domain families : Smart (EMBL)IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  VWC (SM00214)  
Conserved Domain (NCBI)PXDN
DMDM Disease mutations7837
Blocks (Seattle)PXDN
SuperfamilyQ92626
Human Protein AtlasENSG00000130508
Peptide AtlasQ92626
IPIIPI00016112   IPI00791587   IPI00888304   IPI00894357   IPI00894176   
Protein Interaction databases
DIP (DOE-UCLA)Q92626
IntAct (EBI)Q92626
FunCoupENSG00000130508
BioGRIDPXDN
STRING (EMBL)PXDN
ZODIACPXDN
Ontologies - Pathways
QuickGOQ92626
Ontology : AmiGOnegative regulation of cytokine-mediated signaling pathway  peroxidase activity  interleukin-1 receptor antagonist activity  extracellular matrix structural constituent  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum  immune response  response to oxidative stress  heme binding  extracellular matrix organization  extracellular matrix  hydrogen peroxide catabolic process  metal ion binding  oxidation-reduction process  extracellular exosome  cellular oxidant detoxification  cellular oxidant detoxification  
Ontology : EGO-EBInegative regulation of cytokine-mediated signaling pathway  peroxidase activity  interleukin-1 receptor antagonist activity  extracellular matrix structural constituent  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum  immune response  response to oxidative stress  heme binding  extracellular matrix organization  extracellular matrix  hydrogen peroxide catabolic process  metal ion binding  oxidation-reduction process  extracellular exosome  cellular oxidant detoxification  cellular oxidant detoxification  
NDEx NetworkPXDN
Atlas of Cancer Signalling NetworkPXDN
Wikipedia pathwaysPXDN
Orthology - Evolution
OrthoDB7837
GeneTree (enSembl)ENSG00000130508
Phylogenetic Trees/Animal Genes : TreeFamPXDN
HOVERGENQ92626
HOGENOMQ92626
Homologs : HomoloGenePXDN
Homology/Alignments : Family Browser (UCSC)PXDN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPXDN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PXDN
dbVarPXDN
ClinVarPXDN
1000_GenomesPXDN 
Exome Variant ServerPXDN
ExAC (Exome Aggregation Consortium)PXDN (select the gene name)
Genetic variants : HAPMAP7837
Genomic Variants (DGV)PXDN [DGVbeta]
DECIPHER (Syndromes)2:1635659-1748319  ENSG00000130508
CONAN: Copy Number AnalysisPXDN 
Mutations
ICGC Data PortalPXDN 
TCGA Data PortalPXDN 
Broad Tumor PortalPXDN
OASIS PortalPXDN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPXDN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPXDN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PXDN
DgiDB (Drug Gene Interaction Database)PXDN
DoCM (Curated mutations)PXDN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PXDN (select a term)
intoGenPXDN
Cancer3DPXDN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM269400    605158   
Orphanet20730   
MedgenPXDN
Genetic Testing Registry PXDN
NextProtQ92626 [Medical]
TSGene7837
GENETestsPXDN
Huge Navigator PXDN [HugePedia]
snp3D : Map Gene to Disease7837
BioCentury BCIQPXDN
ClinGenPXDN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7837
Chemical/Pharm GKB GenePA128394535
Clinical trialPXDN
Miscellaneous
canSAR (ICR)PXDN (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePXDN
EVEXPXDN
GoPubMedPXDN
iHOPPXDN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:23:45 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.