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PXT1 (peroxisomal testis enriched protein 1)

Identity

Alias_symbol (synonym)STEPP
Other alias
HGNC (Hugo) PXT1
LocusID (NCBI) 222659
Atlas_Id 56031
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 36390551 and ends at 36442889 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PXT1 (6p21.31) / FBXL5 (4p15.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  UBR2/PXT1 (6p21)


External links

Nomenclature
HGNC (Hugo)PXT1   18312
Cards
Entrez_Gene (NCBI)PXT1  222659  peroxisomal testis enriched protein 1
AliasesSTEPP
GeneCards (Weizmann)PXT1
Ensembl hg19 (Hinxton)ENSG00000179165 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179165 [Gene_View]  ENSG00000179165 [Sequence]  chr6:36390551-36442889 [Contig_View]  PXT1 [Vega]
ICGC DataPortalENSG00000179165
TCGA cBioPortalPXT1
AceView (NCBI)PXT1
Genatlas (Paris)PXT1
WikiGenes222659
SOURCE (Princeton)PXT1
Genetics Home Reference (NIH)PXT1
Genomic and cartography
GoldenPath hg38 (UCSC)PXT1  -     chr6:36390551-36442889 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PXT1  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblPXT1 - 6p21.31 [CytoView hg19]  PXT1 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBIPXT1 [Mapview hg19]  PXT1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF486827 BC031105 BC107049
RefSeq transcript (Entrez)NM_152990
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PXT1
Cluster EST : UnigeneHs.520097 [ NCBI ]
CGAP (NCI)Hs.520097
Alternative Splicing GalleryENSG00000179165
Gene ExpressionPXT1 [ NCBI-GEO ]   PXT1 [ EBI - ARRAY_EXPRESS ]   PXT1 [ SEEK ]   PXT1 [ MEM ]
Gene Expression Viewer (FireBrowse)PXT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222659
GTEX Portal (Tissue expression)PXT1
Human Protein AtlasENSG00000179165-PXT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFP0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFP0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFP0
Splice isoforms : SwissVarQ8NFP0
PhosPhoSitePlusQ8NFP0
Domains : Interpro (EBI)PXT1   
Domain families : Pfam (Sanger)PXT1 (PF15214)   
Domain families : Pfam (NCBI)pfam15214   
Conserved Domain (NCBI)PXT1
DMDM Disease mutations222659
Blocks (Seattle)PXT1
SuperfamilyQ8NFP0
Human Protein Atlas [tissue]ENSG00000179165-PXT1 [tissue]
Peptide AtlasQ8NFP0
HPRD17937
IPIIPI00168862   IPI00945333   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFP0
IntAct (EBI)Q8NFP0
FunCoupENSG00000179165
BioGRIDPXT1
STRING (EMBL)PXT1
ZODIACPXT1
Ontologies - Pathways
QuickGOQ8NFP0
Ontology : AmiGOmolecular_function  nucleus  peroxisome  peroxisome  biological_process  positive regulation of apoptotic process  
Ontology : EGO-EBImolecular_function  nucleus  peroxisome  peroxisome  biological_process  positive regulation of apoptotic process  
NDEx NetworkPXT1
Atlas of Cancer Signalling NetworkPXT1
Wikipedia pathwaysPXT1
Orthology - Evolution
OrthoDB222659
GeneTree (enSembl)ENSG00000179165
Phylogenetic Trees/Animal Genes : TreeFamPXT1
HOVERGENQ8NFP0
HOGENOMQ8NFP0
Homologs : HomoloGenePXT1
Homology/Alignments : Family Browser (UCSC)PXT1
Gene fusions - Rearrangements
Fusion : QuiverPXT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPXT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PXT1
dbVarPXT1
ClinVarPXT1
1000_GenomesPXT1 
Exome Variant ServerPXT1
ExAC (Exome Aggregation Consortium)ENSG00000179165
GNOMAD BrowserENSG00000179165
Varsome BrowserPXT1
Genetic variants : HAPMAP222659
Genomic Variants (DGV)PXT1 [DGVbeta]
DECIPHERPXT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPXT1 
Mutations
ICGC Data PortalPXT1 
TCGA Data PortalPXT1 
Broad Tumor PortalPXT1
OASIS PortalPXT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPXT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPXT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PXT1
DgiDB (Drug Gene Interaction Database)PXT1
DoCM (Curated mutations)PXT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PXT1 (select a term)
intoGenPXT1
Cancer3DPXT1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPXT1
MedgenPXT1
Genetic Testing Registry PXT1
NextProtQ8NFP0 [Medical]
TSGene222659
GENETestsPXT1
Target ValidationPXT1
Huge Navigator PXT1 [HugePedia]
snp3D : Map Gene to Disease222659
BioCentury BCIQPXT1
ClinGenPXT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222659
Chemical/Pharm GKB GenePA134958920
Clinical trialPXT1
Miscellaneous
canSAR (ICR)PXT1 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePXT1
EVEXPXT1
GoPubMedPXT1
iHOPPXT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:33:32 CET 2018

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