PYGO1 (pygopus family PHD finger 1)

2014-11-01  

Identity

HGNC
LOCATION
15q21.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 26108
MIM: 606902
HGNC: 30256
Ensembl: ENSG00000171016

Variants:

dbSNP: 26108
ClinVar: 26108
TCGA: ENSG00000171016
COSMIC: PYGO1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171016ENST00000302000Q9Y3Y4
ENSG00000171016ENST00000563719Q9Y3Y4
ENSG00000171016ENST00000645724Q9Y3Y4

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Formation of the beta-catenin:TCF transactivating complexREACTOMER-HSA-201722
Deactivation of the beta-catenin transactivating complexREACTOMER-HSA-3769402

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
184987522008Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.84
204039152010Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.10

Citation

Dessen P

PYGO1 (pygopus family PHD finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72431/pygo1