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PYGO2 (pygopus family PHD finger 2)

Identity

Alias_namespygopus homolog 2 (Drosophila)
Other alias1190004M21Rik
HGNC (Hugo) PYGO2
LocusID (NCBI) 90780
Atlas_Id 45884
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 154957026 and ends at 154961782 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PYGO2 (1q21.3) / FTH1 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PYGO2   30257
Cards
Entrez_Gene (NCBI)PYGO2  90780  pygopus family PHD finger 2
Aliases1190004M21Rik
GeneCards (Weizmann)PYGO2
Ensembl hg19 (Hinxton)ENSG00000163348 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163348 [Gene_View]  chr1:154957026-154961782 [Contig_View]  PYGO2 [Vega]
ICGC DataPortalENSG00000163348
TCGA cBioPortalPYGO2
AceView (NCBI)PYGO2
Genatlas (Paris)PYGO2
WikiGenes90780
SOURCE (Princeton)PYGO2
Genetics Home Reference (NIH)PYGO2
Genomic and cartography
GoldenPath hg38 (UCSC)PYGO2  -     chr1:154957026-154961782 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PYGO2  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblPYGO2 - 1q21.3 [CytoView hg19]  PYGO2 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIPYGO2 [Mapview hg19]  PYGO2 [Mapview hg38]
OMIM606903   
Gene and transcription
Genbank (Entrez)AF289598 AF457208 AK090545 AK092389 AK095425
RefSeq transcript (Entrez)NM_138300
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PYGO2
Cluster EST : UnigeneHs.533597 [ NCBI ]
CGAP (NCI)Hs.533597
Alternative Splicing GalleryENSG00000163348
Gene ExpressionPYGO2 [ NCBI-GEO ]   PYGO2 [ EBI - ARRAY_EXPRESS ]   PYGO2 [ SEEK ]   PYGO2 [ MEM ]
Gene Expression Viewer (FireBrowse)PYGO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90780
GTEX Portal (Tissue expression)PYGO2
Human Protein AtlasENSG00000163348-PYGO2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRQ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRQ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRQ0
Splice isoforms : SwissVarQ9BRQ0
PhosPhoSitePlusQ9BRQ0
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)   
Domains : Interpro (EBI)Zinc_finger_PHD-type_CS    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PHD (PF00628)   
Domain families : Pfam (NCBI)pfam00628   
Domain families : Smart (EMBL)PHD (SM00249)  
Conserved Domain (NCBI)PYGO2
DMDM Disease mutations90780
Blocks (Seattle)PYGO2
PDB (SRS)2XB1    4UP0    4UP5   
PDB (PDBSum)2XB1    4UP0    4UP5   
PDB (IMB)2XB1    4UP0    4UP5   
PDB (RSDB)2XB1    4UP0    4UP5   
Structural Biology KnowledgeBase2XB1    4UP0    4UP5   
SCOP (Structural Classification of Proteins)2XB1    4UP0    4UP5   
CATH (Classification of proteins structures)2XB1    4UP0    4UP5   
SuperfamilyQ9BRQ0
Human Protein Atlas [tissue]ENSG00000163348-PYGO2 [tissue]
Peptide AtlasQ9BRQ0
HPRD06065
IPIIPI00042099   IPI00642524   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRQ0
IntAct (EBI)Q9BRQ0
FunCoupENSG00000163348
BioGRIDPYGO2
STRING (EMBL)PYGO2
ZODIACPYGO2
Ontologies - Pathways
QuickGOQ9BRQ0
Ontology : AmiGOin utero embryonic development  kidney development  lens development in camera-type eye  chromatin binding  protein binding  nucleoplasm  spermatid nucleus differentiation  brain development  zinc ion binding  post-embryonic development  mammary gland development  regulation of mammary gland epithelial cell proliferation  histone acetyltransferase regulator activity  regulation of histone acetylation  positive regulation of chromatin binding  histone binding  developmental growth  regulation of histone H3-K4 methylation  palate development  canonical Wnt signaling pathway  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIin utero embryonic development  kidney development  lens development in camera-type eye  chromatin binding  protein binding  nucleoplasm  spermatid nucleus differentiation  brain development  zinc ion binding  post-embryonic development  mammary gland development  regulation of mammary gland epithelial cell proliferation  histone acetyltransferase regulator activity  regulation of histone acetylation  positive regulation of chromatin binding  histone binding  developmental growth  regulation of histone H3-K4 methylation  palate development  canonical Wnt signaling pathway  beta-catenin-TCF complex assembly  
NDEx NetworkPYGO2
Atlas of Cancer Signalling NetworkPYGO2
Wikipedia pathwaysPYGO2
Orthology - Evolution
OrthoDB90780
GeneTree (enSembl)ENSG00000163348
Phylogenetic Trees/Animal Genes : TreeFamPYGO2
HOVERGENQ9BRQ0
HOGENOMQ9BRQ0
Homologs : HomoloGenePYGO2
Homology/Alignments : Family Browser (UCSC)PYGO2
Gene fusions - Rearrangements
Tumor Fusion PortalPYGO2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPYGO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PYGO2
dbVarPYGO2
ClinVarPYGO2
1000_GenomesPYGO2 
Exome Variant ServerPYGO2
ExAC (Exome Aggregation Consortium)ENSG00000163348
GNOMAD BrowserENSG00000163348
Genetic variants : HAPMAP90780
Genomic Variants (DGV)PYGO2 [DGVbeta]
DECIPHERPYGO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPYGO2 
Mutations
ICGC Data PortalPYGO2 
TCGA Data PortalPYGO2 
Broad Tumor PortalPYGO2
OASIS PortalPYGO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPYGO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPYGO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PYGO2
DgiDB (Drug Gene Interaction Database)PYGO2
DoCM (Curated mutations)PYGO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PYGO2 (select a term)
intoGenPYGO2
Cancer3DPYGO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606903   
Orphanet
DisGeNETPYGO2
MedgenPYGO2
Genetic Testing Registry PYGO2
NextProtQ9BRQ0 [Medical]
TSGene90780
GENETestsPYGO2
Target ValidationPYGO2
Huge Navigator PYGO2 [HugePedia]
snp3D : Map Gene to Disease90780
BioCentury BCIQPYGO2
ClinGenPYGO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90780
Chemical/Pharm GKB GenePA134881185
Clinical trialPYGO2
Miscellaneous
canSAR (ICR)PYGO2 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePYGO2
EVEXPYGO2
GoPubMedPYGO2
iHOPPYGO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:31:09 CET 2017

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