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PYHIN1 (pyrin and HIN domain family member 1)

Identity

Alias_namespyrin and HIN domain family
Alias_symbol (synonym)IFIX
MGC23885
Other alias
HGNC (Hugo) PYHIN1
LocusID (NCBI) 149628
Atlas_Id 43635
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 158931547 and ends at 158977059 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PYHIN1   28894
Cards
Entrez_Gene (NCBI)PYHIN1  149628  pyrin and HIN domain family member 1
AliasesIFIX
GeneCards (Weizmann)PYHIN1
Ensembl hg19 (Hinxton)ENSG00000163564 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163564 [Gene_View]  chr1:158931547-158977059 [Contig_View]  PYHIN1 [Vega]
ICGC DataPortalENSG00000163564
TCGA cBioPortalPYHIN1
AceView (NCBI)PYHIN1
Genatlas (Paris)PYHIN1
WikiGenes149628
SOURCE (Princeton)PYHIN1
Genetics Home Reference (NIH)PYHIN1
Genomic and cartography
GoldenPath hg38 (UCSC)PYHIN1  -     chr1:158931547-158977059 +  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PYHIN1  -     1q23.1   [Description]    (hg19-Feb_2009)
EnsemblPYHIN1 - 1q23.1 [CytoView hg19]  PYHIN1 - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBIPYHIN1 [Mapview hg19]  PYHIN1 [Mapview hg38]
OMIM612677   
Gene and transcription
Genbank (Entrez)AK024890 AK308350 AW518129 AY185344 AY185345
RefSeq transcript (Entrez)NM_152501 NM_198928 NM_198929 NM_198930
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PYHIN1
Cluster EST : UnigeneHs.745322 [ NCBI ]
CGAP (NCI)Hs.745322
Alternative Splicing GalleryENSG00000163564
Gene ExpressionPYHIN1 [ NCBI-GEO ]   PYHIN1 [ EBI - ARRAY_EXPRESS ]   PYHIN1 [ SEEK ]   PYHIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)PYHIN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)149628
GTEX Portal (Tissue expression)PYHIN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6K0P9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6K0P9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6K0P9
Splice isoforms : SwissVarQ6K0P9
PhosPhoSitePlusQ6K0P9
Domaine pattern : Prosite (Expaxy)DAPIN (PS50824)    HIN_200 (PS50834)   
Domains : Interpro (EBI)DAPIN    HIN200/IF120x   
Domain families : Pfam (Sanger)HIN (PF02760)    PYRIN (PF02758)   
Domain families : Pfam (NCBI)pfam02760    pfam02758   
Domain families : Smart (EMBL)PYRIN (SM01289)  
Conserved Domain (NCBI)PYHIN1
DMDM Disease mutations149628
Blocks (Seattle)PYHIN1
SuperfamilyQ6K0P9
Human Protein AtlasENSG00000163564
Peptide AtlasQ6K0P9
HPRD09999
IPIIPI00398847   IPI00397542   IPI00412281   IPI00397544   IPI00103253   IPI00893471   IPI00645957   
Protein Interaction databases
DIP (DOE-UCLA)Q6K0P9
IntAct (EBI)Q6K0P9
FunCoupENSG00000163564
BioGRIDPYHIN1
STRING (EMBL)PYHIN1
ZODIACPYHIN1
Ontologies - Pathways
QuickGOQ6K0P9
Ontology : AmiGOcell cycle  nuclear speck  
Ontology : EGO-EBIcell cycle  nuclear speck  
NDEx NetworkPYHIN1
Atlas of Cancer Signalling NetworkPYHIN1
Wikipedia pathwaysPYHIN1
Orthology - Evolution
OrthoDB149628
GeneTree (enSembl)ENSG00000163564
Phylogenetic Trees/Animal Genes : TreeFamPYHIN1
HOVERGENQ6K0P9
HOGENOMQ6K0P9
Homologs : HomoloGenePYHIN1
Homology/Alignments : Family Browser (UCSC)PYHIN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPYHIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PYHIN1
dbVarPYHIN1
ClinVarPYHIN1
1000_GenomesPYHIN1 
Exome Variant ServerPYHIN1
ExAC (Exome Aggregation Consortium)PYHIN1 (select the gene name)
Genetic variants : HAPMAP149628
Genomic Variants (DGV)PYHIN1 [DGVbeta]
DECIPHERPYHIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPYHIN1 
Mutations
ICGC Data PortalPYHIN1 
TCGA Data PortalPYHIN1 
Broad Tumor PortalPYHIN1
OASIS PortalPYHIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPYHIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPYHIN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PYHIN1
DgiDB (Drug Gene Interaction Database)PYHIN1
DoCM (Curated mutations)PYHIN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PYHIN1 (select a term)
intoGenPYHIN1
Cancer3DPYHIN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612677   
Orphanet
MedgenPYHIN1
Genetic Testing Registry PYHIN1
NextProtQ6K0P9 [Medical]
TSGene149628
GENETestsPYHIN1
Target ValidationPYHIN1
Huge Navigator PYHIN1 [HugePedia]
snp3D : Map Gene to Disease149628
BioCentury BCIQPYHIN1
ClinGenPYHIN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD149628
Chemical/Pharm GKB GenePA134967485
Clinical trialPYHIN1
Miscellaneous
canSAR (ICR)PYHIN1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePYHIN1
EVEXPYHIN1
GoPubMedPYHIN1
iHOPPYHIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:51:57 CEST 2017

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