PZP (PZP alpha-2-macroglobulin like)

2014-11-01  

Identity

HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
CPAMD6
FUSION GENES

Other Information

Locus ID:

NCBI: 5858
MIM: 176420
HGNC: 9750
Ensembl: ENSG00000126838

Variants:

dbSNP: 5858
ClinVar: 5858
TCGA: ENSG00000126838
COSMIC: PZP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126838ENST00000261336P20742
ENSG00000126838ENST00000535230F5GXY0

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
207080052010Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.97
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
191052032009An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.16
218797682011Serum levels of pregnancy zone protein are elevated in presymptomatic Alzheimer's disease.14
308505282019Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer's-associated amyloid beta peptide.6
118119502002Differential binding properties of human pregnancy zone protein- and alpha2-macroglobulin-proteinase complexes to low-density lipoprotein receptor-related protein.5
257370432015Pregnancy Zone Protein is Increased in the Alzheimer's Disease Brain and Associates with Senile Plaques.5
172578542007Proteolytic hydrolysis and purification of the LRP/alfa-2-macroglobulin receptor domain from alpha-macroglobulins.0
304115272019Screening and Identification of Pregnancy Zone Protein and Leucine-Rich Alpha-2-Glycoprotein as Potential Serum Biomarkers for Early-Onset Myocardial Infarction using Protein Profile Analysis.0

Citation

Dessen P

PZP (PZP alpha-2-macroglobulin like)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72436/pzp