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QDPR (quinoid dihydropteridine reductase)

Identity

Alias_symbol (synonym)DHPR
PKU2
SDR33C1
Other alias
HGNC (Hugo) QDPR
LocusID (NCBI) 5860
Atlas_Id 72438
Location 4p15.32  [Link to chromosome band 4p15]
Location_base_pair Starts at 17486393 and ends at 17512234 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
QDPR (4p15.32) / DHX34 (19q13.32)QDPR (4p15.32) / STK40 (1p34.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)QDPR   9752
Cards
Entrez_Gene (NCBI)QDPR  5860  quinoid dihydropteridine reductase
AliasesDHPR; PKU2; SDR33C1
GeneCards (Weizmann)QDPR
Ensembl hg19 (Hinxton)ENSG00000151552 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151552 [Gene_View]  chr4:17486393-17512234 [Contig_View]  QDPR [Vega]
ICGC DataPortalENSG00000151552
TCGA cBioPortalQDPR
AceView (NCBI)QDPR
Genatlas (Paris)QDPR
WikiGenes5860
SOURCE (Princeton)QDPR
Genetics Home Reference (NIH)QDPR
Genomic and cartography
GoldenPath hg38 (UCSC)QDPR  -     chr4:17486393-17512234 -  4p15.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)QDPR  -     4p15.32   [Description]    (hg19-Feb_2009)
EnsemblQDPR - 4p15.32 [CytoView hg19]  QDPR - 4p15.32 [CytoView hg38]
Mapping of homologs : NCBIQDPR [Mapview hg19]  QDPR [Mapview hg38]
OMIM261630   612676   
Gene and transcription
Genbank (Entrez)AK124382 AK223437 AK289773 AK296622 AM393718
RefSeq transcript (Entrez)NM_000320 NM_001306140
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)QDPR
Cluster EST : UnigeneHs.75438 [ NCBI ]
CGAP (NCI)Hs.75438
Alternative Splicing GalleryENSG00000151552
Gene ExpressionQDPR [ NCBI-GEO ]   QDPR [ EBI - ARRAY_EXPRESS ]   QDPR [ SEEK ]   QDPR [ MEM ]
Gene Expression Viewer (FireBrowse)QDPR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5860
GTEX Portal (Tissue expression)QDPR
Human Protein AtlasENSG00000151552-QDPR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09417   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09417  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09417
Splice isoforms : SwissVarP09417
Catalytic activity : Enzyme1.5.1.34 [ Enzyme-Expasy ]   1.5.1.341.5.1.34 [ IntEnz-EBI ]   1.5.1.34 [ BRENDA ]   1.5.1.34 [ KEGG ]   
PhosPhoSitePlusP09417
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)NAD(P)-bd_dom    Sc_DH/Rdtase_CS    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)QDPR
DMDM Disease mutations5860
Blocks (Seattle)QDPR
PDB (SRS)1HDR   
PDB (PDBSum)1HDR   
PDB (IMB)1HDR   
PDB (RSDB)1HDR   
Structural Biology KnowledgeBase1HDR   
SCOP (Structural Classification of Proteins)1HDR   
CATH (Classification of proteins structures)1HDR   
SuperfamilyP09417
Human Protein Atlas [tissue]ENSG00000151552-QDPR [tissue]
Peptide AtlasP09417
HPRD02025
IPIIPI00014439   IPI00902534   IPI00964156   IPI00965443   IPI00964055   IPI00964463   
Protein Interaction databases
DIP (DOE-UCLA)P09417
IntAct (EBI)P09417
FunCoupENSG00000151552
BioGRIDQDPR
STRING (EMBL)QDPR
ZODIACQDPR
Ontologies - Pathways
QuickGOP09417
Ontology : AmiGOliver development  6,7-dihydropteridine reductase activity  cytoplasm  mitochondrion  cytosol  cellular amino acid metabolic process  L-phenylalanine catabolic process  tetrahydrobiopterin biosynthetic process  electron carrier activity  response to aluminum ion  response to lead ion  response to glucagon  cellular response to drug  protein homodimerization activity  neuron projection  dihydrobiopterin metabolic process  oxidation-reduction process  extracellular exosome  NADPH binding  NADH binding  
Ontology : EGO-EBIliver development  6,7-dihydropteridine reductase activity  cytoplasm  mitochondrion  cytosol  cellular amino acid metabolic process  L-phenylalanine catabolic process  tetrahydrobiopterin biosynthetic process  electron carrier activity  response to aluminum ion  response to lead ion  response to glucagon  cellular response to drug  protein homodimerization activity  neuron projection  dihydrobiopterin metabolic process  oxidation-reduction process  extracellular exosome  NADPH binding  NADH binding  
Pathways : KEGGFolate biosynthesis   
NDEx NetworkQDPR
Atlas of Cancer Signalling NetworkQDPR
Wikipedia pathwaysQDPR
Orthology - Evolution
OrthoDB5860
GeneTree (enSembl)ENSG00000151552
Phylogenetic Trees/Animal Genes : TreeFamQDPR
HOVERGENP09417
HOGENOMP09417
Homologs : HomoloGeneQDPR
Homology/Alignments : Family Browser (UCSC)QDPR
Gene fusions - Rearrangements
Tumor Fusion PortalQDPR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerQDPR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)QDPR
dbVarQDPR
ClinVarQDPR
1000_GenomesQDPR 
Exome Variant ServerQDPR
ExAC (Exome Aggregation Consortium)ENSG00000151552
GNOMAD BrowserENSG00000151552
Genetic variants : HAPMAP5860
Genomic Variants (DGV)QDPR [DGVbeta]
DECIPHERQDPR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisQDPR 
Mutations
ICGC Data PortalQDPR 
TCGA Data PortalQDPR 
Broad Tumor PortalQDPR
OASIS PortalQDPR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICQDPR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDQDPR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch QDPR
DgiDB (Drug Gene Interaction Database)QDPR
DoCM (Curated mutations)QDPR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)QDPR (select a term)
intoGenQDPR
Cancer3DQDPR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM261630    612676   
Orphanet457   
DisGeNETQDPR
MedgenQDPR
Genetic Testing Registry QDPR
NextProtP09417 [Medical]
TSGene5860
GENETestsQDPR
Target ValidationQDPR
Huge Navigator QDPR [HugePedia]
snp3D : Map Gene to Disease5860
BioCentury BCIQQDPR
ClinGenQDPR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5860
Chemical/Pharm GKB GenePA34094
Clinical trialQDPR
Miscellaneous
canSAR (ICR)QDPR (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineQDPR
EVEXQDPR
GoPubMedQDPR
iHOPQDPR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:09:03 CET 2017

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