Atlas of Genetics and Cytogenetics in Oncology and Haematology


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QSOX1 (quiescin sulfhydryl oxidase 1)

Identity

Other namesQ6
QSCN6
HGNC (Hugo) QSOX1
LocusID (NCBI) 5768
Atlas_Id 51357
Location 1q25.2
Location_base_pair Starts at 180123968 and ends at 180167169 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FAM114A1 (4p14) / QSOX1 (1q25.2)MLKL (16q23.1) / QSOX1 (1q25.2)POU6F1 (12q13.13) / QSOX1 (1q25.2)
QSOX1 (1q25.2) / QSOX1 (1q25.2)RNF220 (1p34.1) / QSOX1 (1q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)QSOX1   9756
Cards
Entrez_Gene (NCBI)QSOX1  5768  quiescin sulfhydryl oxidase 1
GeneCards (Weizmann)QSOX1
Ensembl hg19 (Hinxton)ENSG00000116260 [Gene_View]  chr1:180123968-180167169 [Contig_View]  QSOX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000116260 [Gene_View]  chr1:180123968-180167169 [Contig_View]  QSOX1 [Vega]
ICGC DataPortalENSG00000116260
TCGA cBioPortalQSOX1
AceView (NCBI)QSOX1
Genatlas (Paris)QSOX1
WikiGenes5768
SOURCE (Princeton)QSOX1
Genomic and cartography
GoldenPath hg19 (UCSC)QSOX1  -     chr1:180123968-180167169 +  1q25.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)QSOX1  -     1q25.2   [Description]    (hg38-Dec_2013)
EnsemblQSOX1 - 1q25.2 [CytoView hg19]  QSOX1 - 1q25.2 [CytoView hg38]
Mapping of homologs : NCBIQSOX1 [Mapview hg19]  QSOX1 [Mapview hg38]
OMIM603120   
Gene and transcription
Genbank (Entrez)AB209280 AF361868 AK092177 AK290842 AK290887
RefSeq transcript (Entrez)NM_001004128 NM_002826
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)QSOX1
Cluster EST : UnigeneHs.744925 [ NCBI ]
CGAP (NCI)Hs.744925
Alternative Splicing : Fast-db (Paris)GSHG0001234
Alternative Splicing GalleryENSG00000116260
Gene ExpressionQSOX1 [ NCBI-GEO ]   QSOX1 [ EBI - ARRAY_EXPRESS ]   QSOX1 [ SEEK ]   QSOX1 [ MEM ]
Gene Expression Viewer (FireBrowse)QSOX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)5768
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00391 (Uniprot)
NextProtO00391  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00391
Splice isoforms : SwissVarO00391 (Swissvar)
Catalytic activity : Enzyme1.8.3.2 [ Enzyme-Expasy ]   1.8.3.21.8.3.2 [ IntEnz-EBI ]   1.8.3.2 [ BRENDA ]   1.8.3.2 [ KEGG ]   
PhosPhoSitePlusO00391
Domaine pattern : Prosite (Expaxy)ERV_ALR (PS51324)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)ERV/ALR_sulphydryl_oxidase    Thioredoxin-like_fold    Thioredoxin_domain   
Domain families : Pfam (Sanger)Evr1_Alr (PF04777)    Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam04777    pfam00085   
DMDM Disease mutations5768
Blocks (Seattle)QSOX1
PDB (SRS)3LLI    3LLK    3Q6O    4IJ3   
PDB (PDBSum)3LLI    3LLK    3Q6O    4IJ3   
PDB (IMB)3LLI    3LLK    3Q6O    4IJ3   
PDB (RSDB)3LLI    3LLK    3Q6O    4IJ3   
Structural Biology KnowledgeBase3LLI    3LLK    3Q6O    4IJ3   
SCOP (Structural Classification of Proteins)3LLI    3LLK    3Q6O    4IJ3   
CATH (Classification of proteins structures)3LLI    3LLK    3Q6O    4IJ3   
SuperfamilyO00391
Human Protein AtlasENSG00000116260
Peptide AtlasO00391
HPRD06785
IPIIPI00003590   IPI00465016   IPI00015916   IPI00152367   IPI00645742   IPI00872013   
Protein Interaction databases
DIP (DOE-UCLA)O00391
IntAct (EBI)O00391
FunCoupENSG00000116260
BioGRIDQSOX1
STRING (EMBL)QSOX1
ZODIACQSOX1
Ontologies - Pathways
QuickGOO00391
Ontology : AmiGOplatelet degranulation  protein disulfide isomerase activity  protein disulfide isomerase activity  extracellular region  extracellular space  Golgi apparatus  protein folding  protein folding  negative regulation of macroautophagy  flavin-linked sulfhydryl oxidase activity  flavin-linked sulfhydryl oxidase activity  integral component of Golgi membrane  platelet alpha granule lumen  intracellular membrane-bounded organelle  intercellular bridge  cell redox homeostasis  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBIplatelet degranulation  protein disulfide isomerase activity  protein disulfide isomerase activity  extracellular region  extracellular space  Golgi apparatus  protein folding  protein folding  negative regulation of macroautophagy  flavin-linked sulfhydryl oxidase activity  flavin-linked sulfhydryl oxidase activity  integral component of Golgi membrane  platelet alpha granule lumen  intracellular membrane-bounded organelle  intercellular bridge  cell redox homeostasis  oxidation-reduction process  extracellular exosome  
NDEx Network
Atlas of Cancer Signalling NetworkQSOX1
Wikipedia pathwaysQSOX1
Orthology - Evolution
OrthoDB5768
GeneTree (enSembl)ENSG00000116260
Phylogenetic Trees/Animal Genes : TreeFamQSOX1
Homologs : HomoloGeneQSOX1
Homology/Alignments : Family Browser (UCSC)QSOX1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerQSOX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)QSOX1
dbVarQSOX1
ClinVarQSOX1
1000_GenomesQSOX1 
Exome Variant ServerQSOX1
ExAC (Exome Aggregation Consortium)QSOX1 (select the gene name)
SNP (GeneSNP Utah)QSOX1
SNP : HGBaseQSOX1
Genetic variants : HAPMAPQSOX1
Genomic Variants (DGV)QSOX1 [DGVbeta]
Mutations
ICGC Data PortalQSOX1 
TCGA Data PortalQSOX1 
Broad Tumor PortalQSOX1
OASIS PortalQSOX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICQSOX1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch QSOX1
DgiDB (Drug Gene Interaction Database)QSOX1
DoCM (Curated mutations)QSOX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)QSOX1 (select a term)
intoGenQSOX1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:180123968-180167169
CONAN: Copy Number AnalysisQSOX1 
Mutations and Diseases : HGMDQSOX1
OMIM603120   
MedgenQSOX1
Genetic Testing Registry QSOX1
NextProtO00391 [Medical]
TSGene5768
GENETestsQSOX1
Huge Navigator QSOX1 [HugePedia]  QSOX1 [HugeCancerGEM]
snp3D : Map Gene to Disease5768
BioCentury BCIQQSOX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5768
Chemical/Pharm GKB GenePA162400559
Clinical trialQSOX1
Miscellaneous
canSAR (ICR)QSOX1 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineQSOX1
GoPubMedQSOX1
iHOPQSOX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Apr 16 18:01:00 CEST 2016

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