Atlas of Genetics and Cytogenetics in Oncology and Haematology


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QSOX2 (quiescin sulfhydryl oxidase 2)

Identity

Alias_namesQSCN6L1
quiescin Q6-like 1
quiescin Q6 sulfhydryl oxidase 2
Alias_symbol (synonym)SOXN
DKFZp762A2013
Other alias
HGNC (Hugo) QSOX2
LocusID (NCBI) 169714
Atlas_Id 54567
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136206337 and ends at 136245841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DHCR24 (1p32.3) / QSOX2 (9q34.3)UBAC1 (9q34.3) / QSOX2 (9q34.3)VAV2 (9q34.2) / QSOX2 (9q34.3)
UBAC1 9q34.3 / QSOX2 9q34.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)QSOX2   30249
Cards
Entrez_Gene (NCBI)QSOX2  169714  quiescin sulfhydryl oxidase 2
AliasesQSCN6L1; SOXN
GeneCards (Weizmann)QSOX2
Ensembl hg19 (Hinxton)ENSG00000165661 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165661 [Gene_View]  chr9:136206337-136245841 [Contig_View]  QSOX2 [Vega]
ICGC DataPortalENSG00000165661
TCGA cBioPortalQSOX2
AceView (NCBI)QSOX2
Genatlas (Paris)QSOX2
WikiGenes169714
SOURCE (Princeton)QSOX2
Genetics Home Reference (NIH)QSOX2
Genomic and cartography
GoldenPath hg38 (UCSC)QSOX2  -     chr9:136206337-136245841 -  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)QSOX2  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblQSOX2 - 9q34.3 [CytoView hg19]  QSOX2 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBIQSOX2 [Mapview hg19]  QSOX2 [Mapview hg38]
OMIM612860   
Gene and transcription
Genbank (Entrez)AJ318051 AJ420461 AK128077 AK128750 AL834369
RefSeq transcript (Entrez)NM_181701
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)QSOX2
Cluster EST : UnigeneHs.144073 [ NCBI ]
CGAP (NCI)Hs.144073
Alternative Splicing GalleryENSG00000165661
Gene ExpressionQSOX2 [ NCBI-GEO ]   QSOX2 [ EBI - ARRAY_EXPRESS ]   QSOX2 [ SEEK ]   QSOX2 [ MEM ]
Gene Expression Viewer (FireBrowse)QSOX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)169714
GTEX Portal (Tissue expression)QSOX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZRP7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZRP7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZRP7
Splice isoforms : SwissVarQ6ZRP7
Catalytic activity : Enzyme1.8.3.2 [ Enzyme-Expasy ]   1.8.3.21.8.3.2 [ IntEnz-EBI ]   1.8.3.2 [ BRENDA ]   1.8.3.2 [ KEGG ]   
PhosPhoSitePlusQ6ZRP7
Domaine pattern : Prosite (Expaxy)ERV_ALR (PS51324)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)ERV/ALR_sulphydryl_oxidase    Thioredoxin-like_fold    Thioredoxin_domain   
Domain families : Pfam (Sanger)Evr1_Alr (PF04777)    Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam04777    pfam00085   
Conserved Domain (NCBI)QSOX2
DMDM Disease mutations169714
Blocks (Seattle)QSOX2
SuperfamilyQ6ZRP7
Human Protein AtlasENSG00000165661
Peptide AtlasQ6ZRP7
HPRD17942
IPIIPI00376394   IPI00514219   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZRP7
IntAct (EBI)Q6ZRP7
FunCoupENSG00000165661
BioGRIDQSOX2
STRING (EMBL)QSOX2
ZODIACQSOX2
Ontologies - Pathways
QuickGOQ6ZRP7
Ontology : AmiGOprotein disulfide isomerase activity  extracellular space  nucleoplasm  Golgi apparatus  plasma membrane  flavin-linked sulfhydryl oxidase activity  integral component of Golgi membrane  nuclear membrane  cell redox homeostasis  oxidation-reduction process  
Ontology : EGO-EBIprotein disulfide isomerase activity  extracellular space  nucleoplasm  Golgi apparatus  plasma membrane  flavin-linked sulfhydryl oxidase activity  integral component of Golgi membrane  nuclear membrane  cell redox homeostasis  oxidation-reduction process  
NDEx NetworkQSOX2
Atlas of Cancer Signalling NetworkQSOX2
Wikipedia pathwaysQSOX2
Orthology - Evolution
OrthoDB169714
GeneTree (enSembl)ENSG00000165661
Phylogenetic Trees/Animal Genes : TreeFamQSOX2
HOVERGENQ6ZRP7
HOGENOMQ6ZRP7
Homologs : HomoloGeneQSOX2
Homology/Alignments : Family Browser (UCSC)QSOX2
Gene fusions - Rearrangements
Fusion : MitelmanUBAC1/QSOX2 [9q34.3/9q34.3]  [t(9;9)(q34;q34)]  
Fusion : MitelmanVAV2/QSOX2 [9q34.2/9q34.3]  [del(9)(q34q34)]  
Fusion: TCGAUBAC1 9q34.3 QSOX2 9q34.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerQSOX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)QSOX2
dbVarQSOX2
ClinVarQSOX2
1000_GenomesQSOX2 
Exome Variant ServerQSOX2
ExAC (Exome Aggregation Consortium)QSOX2 (select the gene name)
Genetic variants : HAPMAP169714
Genomic Variants (DGV)QSOX2 [DGVbeta]
DECIPHERQSOX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisQSOX2 
Mutations
ICGC Data PortalQSOX2 
TCGA Data PortalQSOX2 
Broad Tumor PortalQSOX2
OASIS PortalQSOX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICQSOX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDQSOX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch QSOX2
DgiDB (Drug Gene Interaction Database)QSOX2
DoCM (Curated mutations)QSOX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)QSOX2 (select a term)
intoGenQSOX2
Cancer3DQSOX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612860   
Orphanet
MedgenQSOX2
Genetic Testing Registry QSOX2
NextProtQ6ZRP7 [Medical]
TSGene169714
GENETestsQSOX2
Target ValidationQSOX2
Huge Navigator QSOX2 [HugePedia]
snp3D : Map Gene to Disease169714
BioCentury BCIQQSOX2
ClinGenQSOX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD169714
Chemical/Pharm GKB GenePA162400588
Clinical trialQSOX2
Miscellaneous
canSAR (ICR)QSOX2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineQSOX2
EVEXQSOX2
GoPubMedQSOX2
iHOPQSOX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:51:59 CEST 2017

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