Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RAB11A (RAB11A, member RAS oncogene family)

Identity

Other namesYL8
HGNC (Hugo) RAB11A
LocusID (NCBI) 8766
Atlas_Id 41956
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 66161797 and ends at 66184329 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DENND4A (15q22.31) / RAB11A (15q22.31)RAB11A (15q22.31) / DENND4A (15q22.31)RAB11A (15q22.31) / RAB11A (15q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB11A   9760
Cards
Entrez_Gene (NCBI)RAB11A  8766  RAB11A, member RAS oncogene family
AliasesYL8
GeneCards (Weizmann)RAB11A
Ensembl hg19 (Hinxton)ENSG00000103769 [Gene_View]  chr15:66161797-66184329 [Contig_View]  RAB11A [Vega]
Ensembl hg38 (Hinxton)ENSG00000103769 [Gene_View]  chr15:66161797-66184329 [Contig_View]  RAB11A [Vega]
ICGC DataPortalENSG00000103769
TCGA cBioPortalRAB11A
AceView (NCBI)RAB11A
Genatlas (Paris)RAB11A
WikiGenes8766
SOURCE (Princeton)RAB11A
Genomic and cartography
GoldenPath hg19 (UCSC)RAB11A  -     chr15:66161797-66184329 +  15q22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RAB11A  -     15q22.31   [Description]    (hg38-Dec_2013)
EnsemblRAB11A - 15q22.31 [CytoView hg19]  RAB11A - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIRAB11A [Mapview hg19]  RAB11A [Mapview hg38]
OMIM605570   
Gene and transcription
Genbank (Entrez)AF000231 AF498946 AK054930 AK297549 AK298961
RefSeq transcript (Entrez)NM_001206836 NM_004663
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)RAB11A
Cluster EST : UnigeneHs.321541 [ NCBI ]
CGAP (NCI)Hs.321541
Alternative Splicing GalleryENSG00000103769
Gene ExpressionRAB11A [ NCBI-GEO ]   RAB11A [ EBI - ARRAY_EXPRESS ]   RAB11A [ SEEK ]   RAB11A [ MEM ]
Gene Expression Viewer (FireBrowse)RAB11A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8766
GTEX Portal (Tissue expression)RAB11A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62491 (Uniprot)
NextProtP62491  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62491
Splice isoforms : SwissVarP62491 (Swissvar)
PhosPhoSitePlusP62491
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAB (SM00175)  
DMDM Disease mutations8766
Blocks (Seattle)RAB11A
PDB (SRS)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
PDB (PDBSum)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
PDB (IMB)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
PDB (RSDB)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
Structural Biology KnowledgeBase1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
SCOP (Structural Classification of Proteins)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
CATH (Classification of proteins structures)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4D0L    4D0M    4LWZ    4LX0    4UJ3    4UJ4    4UJ5    5C46    5C4G   
SuperfamilyP62491
Human Protein AtlasENSG00000103769
Peptide AtlasP62491
HPRD05715
IPIIPI01022454   
Protein Interaction databases
DIP (DOE-UCLA)P62491
IntAct (EBI)P62491
FunCoupENSG00000103769
BioGRIDRAB11A
STRING (EMBL)RAB11A
ZODIACRAB11A
Ontologies - Pathways
QuickGOP62491
Ontology : AmiGOcytokinesis  spindle pole  renal water homeostasis  GTPase activity  protein binding  GTP binding  mitochondrion  multivesicular body  Golgi apparatus  trans-Golgi network  centrosome  kinetochore microtubule  cytosol  plasma membrane  intracellular protein transport  nucleocytoplasmic transport  mitotic metaphase plate congression  small GTPase mediated signal transduction  microtubule binding  metabolic process  positive regulation of epithelial cell migration  regulation of multivesicular body size  positive regulation of G2/M transition of mitotic cell cycle  vesicle-mediated transport  syntaxin binding  transport vesicle  axon  cytoplasmic vesicle membrane  astral microtubule organization  neuron projection development  cytoplasmic vesicle  myosin V binding  vesicle  cleavage furrow  melanosome transport  melanosome transport  multivesicular body assembly  protein complex  phagocytic vesicle  positive regulation of axon extension  regulation of long-term neuronal synaptic plasticity  plasma membrane to endosome transport  perinuclear region of cytoplasm  regulation of protein transport  establishment of vesicle localization  recycling endosome  recycling endosome  recycling endosome membrane  regulation of vesicle-mediated transport  extracellular exosome  establishment of protein localization to organelle  protein localization to plasma membrane  establishment of protein localization to membrane  mitotic spindle assembly  exosomal secretion  
Ontology : EGO-EBIcytokinesis  spindle pole  renal water homeostasis  GTPase activity  protein binding  GTP binding  mitochondrion  multivesicular body  Golgi apparatus  trans-Golgi network  centrosome  kinetochore microtubule  cytosol  plasma membrane  intracellular protein transport  nucleocytoplasmic transport  mitotic metaphase plate congression  small GTPase mediated signal transduction  microtubule binding  metabolic process  positive regulation of epithelial cell migration  regulation of multivesicular body size  positive regulation of G2/M transition of mitotic cell cycle  vesicle-mediated transport  syntaxin binding  transport vesicle  axon  cytoplasmic vesicle membrane  astral microtubule organization  neuron projection development  cytoplasmic vesicle  myosin V binding  vesicle  cleavage furrow  melanosome transport  melanosome transport  multivesicular body assembly  protein complex  phagocytic vesicle  positive regulation of axon extension  regulation of long-term neuronal synaptic plasticity  plasma membrane to endosome transport  perinuclear region of cytoplasm  regulation of protein transport  establishment of vesicle localization  recycling endosome  recycling endosome  recycling endosome membrane  regulation of vesicle-mediated transport  extracellular exosome  establishment of protein localization to organelle  protein localization to plasma membrane  establishment of protein localization to membrane  mitotic spindle assembly  exosomal secretion  
Pathways : BIOCARTARab GTPases Mark Targets In The Endocytotic Machinery [Genes]   
Pathways : KEGGEndocytosis    Endocrine and other factor-regulated calcium reabsorption    Vasopressin-regulated water reabsorption    Pancreatic secretion   
NDEx Network
Atlas of Cancer Signalling NetworkRAB11A
Wikipedia pathwaysRAB11A
Orthology - Evolution
OrthoDB8766
GeneTree (enSembl)ENSG00000103769
Phylogenetic Trees/Animal Genes : TreeFamRAB11A
Homologs : HomoloGeneRAB11A
Homology/Alignments : Family Browser (UCSC)RAB11A
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerRAB11A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB11A
dbVarRAB11A
ClinVarRAB11A
1000_GenomesRAB11A 
Exome Variant ServerRAB11A
ExAC (Exome Aggregation Consortium)RAB11A (select the gene name)
Genetic variants : HAPMAP8766
Genomic Variants (DGV)RAB11A [DGVbeta]
Mutations
ICGC Data PortalRAB11A 
TCGA Data PortalRAB11A 
Broad Tumor PortalRAB11A
OASIS PortalRAB11A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB11A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RAB11A
DgiDB (Drug Gene Interaction Database)RAB11A
DoCM (Curated mutations)RAB11A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB11A (select a term)
intoGenRAB11A
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)15:66161797-66184329  ENSG00000103769
CONAN: Copy Number AnalysisRAB11A 
Mutations and Diseases : HGMDRAB11A
OMIM605570   
MedgenRAB11A
Genetic Testing Registry RAB11A
NextProtP62491 [Medical]
TSGene8766
GENETestsRAB11A
Huge Navigator RAB11A [HugePedia]
snp3D : Map Gene to Disease8766
BioCentury BCIQRAB11A
ClinGenRAB11A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8766
Chemical/Pharm GKB GenePA34101
Clinical trialRAB11A
Miscellaneous
canSAR (ICR)RAB11A (select the gene name)
Probes
Litterature
PubMed153 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB11A
EVEXRAB11A
GoPubMedRAB11A
iHOPRAB11A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:12:56 CEST 2016

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