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RAB11A (RAB11A, member RAS oncogene family)

Identity

Other namesYL8
HGNC (Hugo) RAB11A
LocusID (NCBI) 8766
Location 15q22.31
Location_base_pair Starts at 66161797 and ends at 66184329 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RAB11A   9760
Cards
Entrez_Gene (NCBI)RAB11A  8766  RAB11A, member RAS oncogene family
GeneCards (Weizmann)RAB11A
Ensembl hg19 (Hinxton)ENSG00000103769 [Gene_View]  chr15:66161797-66184329 [Contig_View]  RAB11A [Vega]
Ensembl hg38 (Hinxton)ENSG00000103769 [Gene_View]  chr15:66161797-66184329 [Contig_View]  RAB11A [Vega]
ICGC DataPortalENSG00000103769
cBioPortalRAB11A
AceView (NCBI)RAB11A
Genatlas (Paris)RAB11A
WikiGenes8766
SOURCE (Princeton)RAB11A
Genomic and cartography
GoldenPath hg19 (UCSC)RAB11A  -     chr15:66161797-66184329 +  15q22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RAB11A  -     15q22.31   [Description]    (hg38-Dec_2013)
EnsemblRAB11A - 15q22.31 [CytoView hg19]  RAB11A - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIRAB11A [Mapview hg19]  RAB11A [Mapview hg38]
OMIM605570   
Gene and transcription
Genbank (Entrez)AF000231 AF498946 AK054930 AK297549 AK298961
RefSeq transcript (Entrez)NM_001206836 NM_004663
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NT_010194 NW_001838218 NW_004929398
Consensus coding sequences : CCDS (NCBI)RAB11A
Cluster EST : UnigeneHs.321541 [ NCBI ]
CGAP (NCI)Hs.321541
Alternative Splicing : Fast-db (Paris)GSHG0009943
Alternative Splicing GalleryENSG00000103769
Gene ExpressionRAB11A [ NCBI-GEO ]     RAB11A [ SEEK ]   RAB11A [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62491 (Uniprot)
NextProtP62491  [Medical]
With graphics : InterProP62491
Splice isoforms : SwissVarP62491 (Swissvar)
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Related proteins : CluSTrP62491
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAB (SM00175)  
DMDM Disease mutations8766
Blocks (Seattle)P62491
PDB (SRS)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4LWZ    4LX0   
PDB (PDBSum)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4LWZ    4LX0   
PDB (IMB)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4LWZ    4LX0   
PDB (RSDB)1OIV    1OIW    1OIX    1YZK    2D7C    2GZD    2GZH    2HV8    4C4P    4LWZ    4LX0   
Human Protein AtlasENSG00000103769
Peptide AtlasP62491
HPRD05715
IPIIPI01022454   
Protein Interaction databases
DIP (DOE-UCLA)P62491
IntAct (EBI)P62491
FunCoupENSG00000103769
BioGRIDRAB11A
IntegromeDBRAB11A
STRING (EMBL)RAB11A
Ontologies - Pathways
QuickGOP62491
Ontology : AmiGOcytokinesis  GTPase activity  protein binding  GTP binding  mitochondrion  trans-Golgi network  plasma membrane  GTP catabolic process  water transport  small GTPase mediated signal transduction  protein transport  vesicle-mediated transport  syntaxin binding  transport vesicle  axon  cytoplasmic vesicle membrane  phagocytic vesicle membrane  neuron projection development  cleavage furrow  melanosome transport  protein complex  phagocytic vesicle  positive regulation of axon extension  regulation of long-term neuronal synaptic plasticity  plasma membrane to endosome transport  perinuclear region of cytoplasm  regulation of protein transport  recycling endosome  recycling endosome membrane  transmembrane transport  extracellular vesicular exosome  protein localization to plasma membrane  
Ontology : EGO-EBIcytokinesis  GTPase activity  protein binding  GTP binding  mitochondrion  trans-Golgi network  plasma membrane  GTP catabolic process  water transport  small GTPase mediated signal transduction  protein transport  vesicle-mediated transport  syntaxin binding  transport vesicle  axon  cytoplasmic vesicle membrane  phagocytic vesicle membrane  neuron projection development  cleavage furrow  melanosome transport  protein complex  phagocytic vesicle  positive regulation of axon extension  regulation of long-term neuronal synaptic plasticity  plasma membrane to endosome transport  perinuclear region of cytoplasm  regulation of protein transport  recycling endosome  recycling endosome membrane  transmembrane transport  extracellular vesicular exosome  protein localization to plasma membrane  
Pathways : BIOCARTARab GTPases Mark Targets In The Endocytotic Machinery [Genes]   
Pathways : KEGGEndocytosis    Endocrine and other factor-regulated calcium reabsorption    Vasopressin-regulated water reabsorption    Pancreatic secretion   
Protein Interaction DatabaseRAB11A
DoCM (Curated mutations)RAB11A
Wikipedia pathwaysRAB11A
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerRAB11A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB11A
dbVarRAB11A
ClinVarRAB11A
1000_GenomesRAB11A 
Exome Variant ServerRAB11A
SNP (GeneSNP Utah)RAB11A
SNP : HGBaseRAB11A
Genetic variants : HAPMAPRAB11A
Genomic VariantsRAB11A  RAB11A [DGVbeta]
Mutations
ICGC Data PortalENSG00000103769 
Somatic Mutations in Cancer : COSMICRAB11A 
CONAN: Copy Number AnalysisRAB11A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)15:66161797-66184329
Mutations and Diseases : HGMDRAB11A
OMIM605570   
MedgenRAB11A
NextProtP62491 [Medical]
GENETestsRAB11A
Disease Genetic AssociationRAB11A
Huge Navigator RAB11A [HugePedia]  RAB11A [HugeCancerGEM]
snp3D : Map Gene to Disease8766
DGIdb (Drug Gene Interaction db)RAB11A
General knowledge
Homologs : HomoloGeneRAB11A
Homology/Alignments : Family Browser (UCSC)RAB11A
Phylogenetic Trees/Animal Genes : TreeFamRAB11A
Chemical/Protein Interactions : CTD8766
Chemical/Pharm GKB GenePA34101
Clinical trialRAB11A
Cancer Resource (Charite)ENSG00000103769
Other databases
Probes
Litterature
PubMed122 Pubmed reference(s) in Entrez
CoreMineRAB11A
GoPubMedRAB11A
iHOPRAB11A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 01:04:23 CET 2014

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