RAB11A (RAB11A, member RAS oncogene family)

2003-11-01  

Identity

HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
YL8
FUSION GENES

Other Information

Locus ID:

NCBI: 8766
MIM: 605570
HGNC: 9760
Ensembl: ENSG00000103769

Variants:

dbSNP: 8766
ClinVar: 8766
TCGA: ENSG00000103769
COSMIC: RAB11A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103769ENST00000261890P62491
ENSG00000103769ENST00000261890A0A024R5Z8
ENSG00000103769ENST00000564910B4DQU5
ENSG00000103769ENST00000565075H3BSC1
ENSG00000103769ENST00000566233H3BMH2
ENSG00000103769ENST00000567671H3BN38
ENSG00000103769ENST00000569896P62491

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Endocrine and other factor-regulated calcium reabsorptionKEGGko04961
Endocrine and other factor-regulated calcium reabsorptionKEGGhsa04961
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Anchoring of the basal body to the plasma membraneREACTOMER-HSA-5620912
Cargo trafficking to the periciliary membraneREACTOMER-HSA-5620920
VxPx cargo-targeting to ciliumREACTOMER-HSA-5620916
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Vasopressin regulates renal water homeostasis via AquaporinsREACTOMER-HSA-432040
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203085582010Coordination of Rab8 and Rab11 in primary ciliogenesis.210
212735062011Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.183
226138322012TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.140
226853252012Rab11 regulates exocytosis of recycling vesicles at the plasma membrane.103
209334422010The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.86
213071882011A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA.86
203570862010The Rab11 pathway is required for influenza A virus budding and filament formation.83
215867482011Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output.83
212826562011Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.75
200266452010Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment.68

Citation

Dessen P

RAB11A (RAB11A, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41956/rab11a