RAB11B (RAB11B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
H-YPT3,NDAGSCW
FUSION GENES

Other Information

Locus ID:

NCBI: 9230
MIM: 604198
HGNC: 9761
Ensembl: ENSG00000185236

Variants:

dbSNP: 9230
ClinVar: 9230
TCGA: ENSG00000185236
COSMIC: RAB11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185236ENST00000328024Q15907
ENSG00000185236ENST00000594216Q15907
ENSG00000185236ENST00000600719M0R377
ENSG00000185236ENST00000601897M0R2D0

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719

References

Pubmed IDYearTitleCitations
335243902021Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation.9
335243902021Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation.9
325417982020Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth.26
325417982020Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth.26
309816672019A role for Rab11 in the homeostasis of the endosome-lysosomal pathway.15
309816672019A role for Rab11 in the homeostasis of the endosome-lysosomal pathway.15
291068252017Recurrent De Novo Mutations Disturbing the GTP/GDP Binding Pocket of RAB11B Cause Intellectual Disability and a Distinctive Brain Phenotype.24
291068252017Recurrent De Novo Mutations Disturbing the GTP/GDP Binding Pocket of RAB11B Cause Intellectual Disability and a Distinctive Brain Phenotype.24
266353652016Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.21
274815172016Rab11a sustains GSK3β/Wnt/β-catenin signaling to enhance cancer progression in pancreatic cancer.23
266353652016Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.21
274815172016Rab11a sustains GSK3β/Wnt/β-catenin signaling to enhance cancer progression in pancreatic cancer.23
241419072014Rab11b mediates melanin transfer between donor melanocytes and acceptor keratinocytes via coupled exo/endocytosis.46
245890862014Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling.8
250708902014Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions.11

Citation

Dessen P

RAB11B (RAB11B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41957/rab11b