RAB11FIP5 (RAB11 family interacting protein 5)

2008-08-01  

Identity

HGNC
RAB11FIP5
LOCATION
2p13.2
LOCUSID
26056
ALIAS
GAF1,RIP11,gaf-1,pp75,rab11-FIP5

Other Information

Locus ID:

NCBI: 26056
MIM: 605536
HGNC: 24845
Ensembl: ENSG00000135631

Variants:

dbSNP: 26056
ClinVar: 26056
TCGA: ENSG00000135631
COSMIC: RAB11FIP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135631ENST00000258098Q9BXF6
ENSG00000135631ENST00000486777A0A1B0GTL5

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
189575122008The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.79
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
245915682014FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis.30
219694672011Interaction between FIP5 and SNX18 regulates epithelial lumen formation.22
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
207179562011Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts.13
178547692007FIP2 and Rip11 specify Rab11a-mediated cellular distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells.12
183840582008A de novo apparently balanced translocation [46,XY,t(2;9)(p13;p24)] interrupting RAB11FIP5 identifies a potential candidate gene for autism spectrum disorder.7
319883822020FERARI is required for Rab11-dependent endocytic recycling.0

Citation

Dessen P

RAB11FIP5 (RAB11 family interacting protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50284/rab11fip5