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RAB12 (RAB12, member RAS oncogene family)

Identity

Other alias-
HGNC (Hugo) RAB12
LocusID (NCBI) 201475
Atlas_Id 43038
Location 18p11.22  [Link to chromosome band 18p11]
Location_base_pair Starts at 8609445 and ends at 8639382 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C20orf96 (20p13) / RAB12 (18p11.22)JADE1 (4q28.2) / RAB12 (18p11.22)PPP1R1B (17q12) / RAB12 (18p11.22)
RAB12 (18p11.22) / FAM19A2 (12q14.1)RAB12 18p11.22 / FAM19A2 12q14.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB12   31332
Cards
Entrez_Gene (NCBI)RAB12  201475  RAB12, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB12
Ensembl hg19 (Hinxton)ENSG00000206418 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000206418 [Gene_View]  chr18:8609445-8639382 [Contig_View]  RAB12 [Vega]
ICGC DataPortalENSG00000206418
TCGA cBioPortalRAB12
AceView (NCBI)RAB12
Genatlas (Paris)RAB12
WikiGenes201475
SOURCE (Princeton)RAB12
Genetics Home Reference (NIH)RAB12
Genomic and cartography
GoldenPath hg38 (UCSC)RAB12  -     chr18:8609445-8639382 +  18p11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB12  -     18p11.22   [Description]    (hg19-Feb_2009)
EnsemblRAB12 - 18p11.22 [CytoView hg19]  RAB12 - 18p11.22 [CytoView hg38]
Mapping of homologs : NCBIRAB12 [Mapview hg19]  RAB12 [Mapview hg38]
OMIM616448   
Gene and transcription
Genbank (Entrez)AK127824 BC050338 BC071600 BC098407
RefSeq transcript (Entrez)NM_001025300
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB12
Cluster EST : UnigeneHs.270074 [ NCBI ]
CGAP (NCI)Hs.270074
Alternative Splicing GalleryENSG00000206418
Gene ExpressionRAB12 [ NCBI-GEO ]   RAB12 [ EBI - ARRAY_EXPRESS ]   RAB12 [ SEEK ]   RAB12 [ MEM ]
Gene Expression Viewer (FireBrowse)RAB12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201475
GTEX Portal (Tissue expression)RAB12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6IQ22   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6IQ22  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6IQ22
Splice isoforms : SwissVarQ6IQ22
PhosPhoSitePlusQ6IQ22
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB12
DMDM Disease mutations201475
Blocks (Seattle)RAB12
PDB (SRS)2IL1   
PDB (PDBSum)2IL1   
PDB (IMB)2IL1   
PDB (RSDB)2IL1   
Structural Biology KnowledgeBase2IL1   
SCOP (Structural Classification of Proteins)2IL1   
CATH (Classification of proteins structures)2IL1   
SuperfamilyQ6IQ22
Human Protein AtlasENSG00000206418
Peptide AtlasQ6IQ22
IPIIPI00419932   
Protein Interaction databases
DIP (DOE-UCLA)Q6IQ22
IntAct (EBI)Q6IQ22
FunCoupENSG00000206418
BioGRIDRAB12
STRING (EMBL)RAB12
ZODIACRAB12
Ontologies - Pathways
QuickGOQ6IQ22
Ontology : AmiGOGolgi membrane  GTPase activity  protein binding  GTP binding  lysosome  lysosomal membrane  endosome  autophagosome  Golgi apparatus  cytosol  autophagy  endosome to lysosome transport  protein transport  positive regulation of macroautophagy  GDP binding  cellular protein catabolic process  recycling endosome membrane  recycling endosome membrane  membrane organization  
Ontology : EGO-EBIGolgi membrane  GTPase activity  protein binding  GTP binding  lysosome  lysosomal membrane  endosome  autophagosome  Golgi apparatus  cytosol  autophagy  endosome to lysosome transport  protein transport  positive regulation of macroautophagy  GDP binding  cellular protein catabolic process  recycling endosome membrane  recycling endosome membrane  membrane organization  
NDEx NetworkRAB12
Atlas of Cancer Signalling NetworkRAB12
Wikipedia pathwaysRAB12
Orthology - Evolution
OrthoDB201475
GeneTree (enSembl)ENSG00000206418
Phylogenetic Trees/Animal Genes : TreeFamRAB12
HOVERGENQ6IQ22
HOGENOMQ6IQ22
Homologs : HomoloGeneRAB12
Homology/Alignments : Family Browser (UCSC)RAB12
Gene fusions - Rearrangements
Fusion : MitelmanRAB12/FAM19A2 [18p11.22/12q14.1]  
Fusion: TCGARAB12 18p11.22 FAM19A2 12q14.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB12
dbVarRAB12
ClinVarRAB12
1000_GenomesRAB12 
Exome Variant ServerRAB12
ExAC (Exome Aggregation Consortium)RAB12 (select the gene name)
Genetic variants : HAPMAP201475
Genomic Variants (DGV)RAB12 [DGVbeta]
DECIPHERRAB12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB12 
Mutations
ICGC Data PortalRAB12 
TCGA Data PortalRAB12 
Broad Tumor PortalRAB12
OASIS PortalRAB12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAB12
DgiDB (Drug Gene Interaction Database)RAB12
DoCM (Curated mutations)RAB12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB12 (select a term)
intoGenRAB12
Cancer3DRAB12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616448   
Orphanet
MedgenRAB12
Genetic Testing Registry RAB12
NextProtQ6IQ22 [Medical]
TSGene201475
GENETestsRAB12
Huge Navigator RAB12 [HugePedia]
snp3D : Map Gene to Disease201475
BioCentury BCIQRAB12
ClinGenRAB12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201475
Chemical/Pharm GKB GenePA142671102
Clinical trialRAB12
Miscellaneous
canSAR (ICR)RAB12 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB12
EVEXRAB12
GoPubMedRAB12
iHOPRAB12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:33:44 CEST 2017

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