RAB15 (RAB15, member RAS oncogene family)

2006-10-01  

Identity

HGNC
RAB15
LOCATION
14q23.3
LOCUSID
376267
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 376267
HGNC: 20150
Ensembl: ENSG00000139998

Variants:

dbSNP: 376267
ClinVar: 376267
TCGA: ENSG00000139998
COSMIC: RAB15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139998ENST00000267512P59190
ENSG00000139998ENST00000426039G3V196
ENSG00000139998ENST00000533601P59190
ENSG00000139998ENST00000533601G5EMR8
ENSG00000139998ENST00000554593G3V562
ENSG00000139998ENST00000585059J3QSF4
ENSG00000139998ENST00000642625A0A2R8YDI9
ENSG00000139998ENST00000646728A0A2R8Y7G7
ENSG00000139998ENST00000646754A0A2R8YFB8

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.6
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.5
161953512005Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment.0
214910862011Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells.0

Citation

Dessen P

RAB15 (RAB15, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43441/rab15