RAB17 (RAB17, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 64284
MIM: 602206
HGNC: 16523
Ensembl: ENSG00000124839

Variants:

dbSNP: 64284
ClinVar: 64284
TCGA: ENSG00000124839
COSMIC: RAB17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124839ENST00000264601Q9H0T7
ENSG00000124839ENST00000264601A0A024R4A4
ENSG00000124839ENST00000392001F8WAG1
ENSG00000124839ENST00000409576B8ZZM5
ENSG00000124839ENST00000409822Q9H0T7
ENSG00000124839ENST00000411462C9J0T6
ENSG00000124839ENST00000414278F8WBE9
ENSG00000124839ENST00000430445H7C1P7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
223285292012ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.25
212915022011The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking.23
250524082014Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion.17
257073552015Rab17 inhibits the tumourigenic properties of hepatocellular carcinomas via the Erk pathway.8
280050732016Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis.6
261911892015Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk pathway.5
284712612019Rab17 mediates intermixing of phagocytosed apoptotic cells with recycling endosomes.1

Citation

Dessen P

RAB17 (RAB17, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41960/rab17