RAB18 (RAB18, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
10p12.1
LOCUSID
ALIAS
RAB18LI1,WARBM3
FUSION GENES

Other Information

Locus ID:

NCBI: 22931
MIM: 602207
HGNC: 14244
Ensembl: ENSG00000099246

Variants:

dbSNP: 22931
ClinVar: 22931
TCGA: ENSG00000099246
COSMIC: RAB18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099246ENST00000356940Q9NP72
ENSG00000099246ENST00000375802Q5W0J0
ENSG00000099246ENST00000423465H0Y6T8
ENSG00000099246ENST00000535776Q9NP72
ENSG00000099246ENST00000611151A0A087X163
ENSG00000099246ENST00000621805Q9NP72

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-independent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811436
Neutrophil degranulationREACTOMER-HSA-6798695
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381390062023Rab18 Drift in Lipid Droplet and Endoplasmic Reticulum Interactions of Adipocytes under Obesogenic Conditions.0
381390062023Rab18 Drift in Lipid Droplet and Endoplasmic Reticulum Interactions of Adipocytes under Obesogenic Conditions.0
322486202021The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.12
339043782021Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.4
322486202021The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.12
339043782021Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.4
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9
327409042020Micro and Martsolf syndromes in 34 new patients: Refining the phenotypic spectrum and further molecular insights.4
325259922020Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.9
327409042020Micro and Martsolf syndromes in 34 new patients: Refining the phenotypic spectrum and further molecular insights.4
308302382019Rab18: new insights into the function of an essential protein.18
315634212019RAB18 modulates autophagy in human stellate cells.5
316109142019Rab18 regulates lipolysis via Arf/GBF1 and adipose triglyceride lipase.3
308302382019Rab18: new insights into the function of an essential protein.18
315634212019RAB18 modulates autophagy in human stellate cells.5

Citation

Dessen P

RAB18 (RAB18, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41961/rab18