Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RAB18 (RAB18, member RAS oncogene family)

Identity

Other aliasRAB18LI1
WARBM3
HGNC (Hugo) RAB18
LocusID (NCBI) 22931
Atlas_Id 41961
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 27504174 and ends at 27542237 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAGED1 (Xp11.22) / RAB18 (10p12.1)RAB18 (10p12.1) / FSTL1 (3q13.33)RAB18 (10p12.1) / RAB18 (10p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RAB18   14244
Cards
Entrez_Gene (NCBI)RAB18  22931  RAB18, member RAS oncogene family
AliasesRAB18LI1; WARBM3
GeneCards (Weizmann)RAB18
Ensembl hg19 (Hinxton)ENSG00000099246 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099246 [Gene_View]  ENSG00000099246 [Sequence]  chr10:27504174-27542237 [Contig_View]  RAB18 [Vega]
ICGC DataPortalENSG00000099246
TCGA cBioPortalRAB18
AceView (NCBI)RAB18
Genatlas (Paris)RAB18
WikiGenes22931
SOURCE (Princeton)RAB18
Genetics Home Reference (NIH)RAB18
Genomic and cartography
GoldenPath hg38 (UCSC)RAB18  -     chr10:27504174-27542237 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB18  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblRAB18 - 2q37.3 [CytoView hg19]  RAB18 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBIRAB18 [Mapview hg19]  RAB18 [Mapview hg38]
OMIM602207   614222   
Gene and transcription
Genbank (Entrez)AB209698 AF087860 AF136974 AF137372 AF498950
RefSeq transcript (Entrez)NM_001256410 NM_001256411 NM_001256412 NM_001256415 NM_021252
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB18
Cluster EST : UnigeneHs.406799 [ NCBI ]
CGAP (NCI)Hs.406799
Alternative Splicing GalleryENSG00000099246
Gene ExpressionRAB18 [ NCBI-GEO ]   RAB18 [ EBI - ARRAY_EXPRESS ]   RAB18 [ SEEK ]   RAB18 [ MEM ]
Gene Expression Viewer (FireBrowse)RAB18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22931
GTEX Portal (Tissue expression)RAB18
Human Protein AtlasENSG00000099246-RAB18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP72   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP72  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP72
Splice isoforms : SwissVarQ9NP72
PhosPhoSitePlusQ9NP72
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Sigma_54_int_dom_ATP-bd_1    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB18
DMDM Disease mutations22931
Blocks (Seattle)RAB18
PDB (SRS)1X3S   
PDB (PDBSum)1X3S   
PDB (IMB)1X3S   
PDB (RSDB)1X3S   
Structural Biology KnowledgeBase1X3S   
SCOP (Structural Classification of Proteins)1X3S   
CATH (Classification of proteins structures)1X3S   
SuperfamilyQ9NP72
Human Protein Atlas [tissue]ENSG00000099246-RAB18 [tissue]
Peptide AtlasQ9NP72
HPRD03731
IPIIPI00014577   IPI00922800   IPI00921855   IPI00844361   IPI00385241   IPI00382462   IPI00479988   IPI00478787   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP72
IntAct (EBI)Q9NP72
FunCoupENSG00000099246
BioGRIDRAB18
STRING (EMBL)RAB18
ZODIACRAB18
Ontologies - Pathways
QuickGOQ9NP72
Ontology : AmiGOeye development  GTPase activity  GTPase activity  protein binding  GTP binding  intracellular  endoplasmic reticulum membrane  Golgi apparatus  cytosol  plasma membrane  intracellular protein transport  small GTPase mediated signal transduction  brain development  endomembrane system  protein transport  GDP binding  secretory granule membrane  Rab protein signal transduction  lipid particle organization  lipid particle organization  neutrophil degranulation  import into nucleus  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network organization  
Ontology : EGO-EBIeye development  GTPase activity  GTPase activity  protein binding  GTP binding  intracellular  endoplasmic reticulum membrane  Golgi apparatus  cytosol  plasma membrane  intracellular protein transport  small GTPase mediated signal transduction  brain development  endomembrane system  protein transport  GDP binding  secretory granule membrane  Rab protein signal transduction  lipid particle organization  lipid particle organization  neutrophil degranulation  import into nucleus  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network organization  
NDEx NetworkRAB18
Atlas of Cancer Signalling NetworkRAB18
Wikipedia pathwaysRAB18
Orthology - Evolution
OrthoDB22931
GeneTree (enSembl)ENSG00000099246
Phylogenetic Trees/Animal Genes : TreeFamRAB18
HOVERGENQ9NP72
HOGENOMQ9NP72
Homologs : HomoloGeneRAB18
Homology/Alignments : Family Browser (UCSC)RAB18
Gene fusions - Rearrangements
Fusion : QuiverRAB18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB18
dbVarRAB18
ClinVarRAB18
1000_GenomesRAB18 
Exome Variant ServerRAB18
ExAC (Exome Aggregation Consortium)ENSG00000099246
GNOMAD BrowserENSG00000099246
Varsome BrowserRAB18
Genetic variants : HAPMAP22931
Genomic Variants (DGV)RAB18 [DGVbeta]
DECIPHERRAB18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB18 
Mutations
ICGC Data PortalRAB18 
TCGA Data PortalRAB18 
Broad Tumor PortalRAB18
OASIS PortalRAB18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MRC Human Genetics Unit LOVD at MRC IGMM
BioMutasearch RAB18
DgiDB (Drug Gene Interaction Database)RAB18
DoCM (Curated mutations)RAB18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB18 (select a term)
intoGenRAB18
Cancer3DRAB18(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602207    614222   
Orphanet2322   
DisGeNETRAB18
MedgenRAB18
Genetic Testing Registry RAB18
NextProtQ9NP72 [Medical]
TSGene22931
GENETestsRAB18
Target ValidationRAB18
Huge Navigator RAB18 [HugePedia]
snp3D : Map Gene to Disease22931
BioCentury BCIQRAB18
ClinGenRAB18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22931
Chemical/Pharm GKB GenePA34106
Clinical trialRAB18
Miscellaneous
canSAR (ICR)RAB18 (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB18
EVEXRAB18
GoPubMedRAB18
iHOPRAB18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Aug 16 11:26:46 CEST 2018
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