Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RAB18 (RAB18, member RAS oncogene family)

Identity

Alias (NCBI)RAB18LI1
WARBM3
HGNC (Hugo) RAB18
LocusID (NCBI) 22931
Atlas_Id 41961
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 27504304 and ends at 27542239 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAGED1 (Xp11.22) / RAB18 (10p12.1)RAB18 (10p12.1) / FSTL1 (3q13.33)RAB18 (10p12.1) / RAB18 (10p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)RAB18   14244
Cards
Entrez_Gene (NCBI)RAB18    RAB18, member RAS oncogene family
AliasesRAB18LI1; WARBM3
GeneCards (Weizmann)RAB18
Ensembl hg19 (Hinxton)ENSG00000099246 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099246 [Gene_View]  ENSG00000099246 [Sequence]  chr10:27504304-27542239 [Contig_View]  RAB18 [Vega]
ICGC DataPortalENSG00000099246
TCGA cBioPortalRAB18
AceView (NCBI)RAB18
Genatlas (Paris)RAB18
SOURCE (Princeton)RAB18
Genetics Home Reference (NIH)RAB18
Genomic and cartography
GoldenPath hg38 (UCSC)RAB18  -     chr10:27504304-27542239 +  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB18  -     10p12.1   [Description]    (hg19-Feb_2009)
GoldenPathRAB18 - 10p12.1 [CytoView hg19]  RAB18 - 10p12.1 [CytoView hg38]
ImmunoBaseENSG00000099246
Genome Data Viewer NCBIRAB18 [Mapview hg19]  
OMIM602207   614222   
Gene and transcription
Genbank (Entrez)AB209698 AF087860 AF136974 AF137372 AF498950
RefSeq transcript (Entrez)NM_001256410 NM_001256411 NM_001256412 NM_001256415 NM_021252
Consensus coding sequences : CCDS (NCBI)RAB18
Gene ExpressionRAB18 [ NCBI-GEO ]   RAB18 [ EBI - ARRAY_EXPRESS ]   RAB18 [ SEEK ]   RAB18 [ MEM ]
Gene Expression Viewer (FireBrowse)RAB18 [ Firebrowse - Broad ]
GenevisibleExpression of RAB18 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22931
GTEX Portal (Tissue expression)RAB18
Human Protein AtlasENSG00000099246-RAB18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP72   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP72  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP72
PhosPhoSitePlusQ9NP72
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Sigma_54_int_dom_ATP-bd_1    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB18
PDB (RSDB)1X3S   
PDB Europe1X3S   
PDB (PDBSum)1X3S   
PDB (IMB)1X3S   
Structural Biology KnowledgeBase1X3S   
SCOP (Structural Classification of Proteins)1X3S   
CATH (Classification of proteins structures)1X3S   
SuperfamilyQ9NP72
AlphaFold pdb e-kbQ9NP72   
Human Protein Atlas [tissue]ENSG00000099246-RAB18 [tissue]
HPRD03731
Protein Interaction databases
DIP (DOE-UCLA)Q9NP72
IntAct (EBI)Q9NP72
BioGRIDRAB18
STRING (EMBL)RAB18
ZODIACRAB18
Ontologies - Pathways
QuickGOQ9NP72
Ontology : AmiGOeye development  GTPase activity  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  Golgi apparatus  lipid droplet  cytosol  plasma membrane  intracellular protein transport  small GTPase mediated signal transduction  brain development  endomembrane system  apical plasma membrane  GDP binding  secretory granule membrane  lipid droplet organization  lipid droplet organization  neutrophil degranulation  synapse  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network organization  
Ontology : EGO-EBIeye development  GTPase activity  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  Golgi apparatus  lipid droplet  cytosol  plasma membrane  intracellular protein transport  small GTPase mediated signal transduction  brain development  endomembrane system  apical plasma membrane  GDP binding  secretory granule membrane  lipid droplet organization  lipid droplet organization  neutrophil degranulation  synapse  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network organization  
NDEx NetworkRAB18
Atlas of Cancer Signalling NetworkRAB18
Wikipedia pathwaysRAB18
Orthology - Evolution
OrthoDB22931
GeneTree (enSembl)ENSG00000099246
Phylogenetic Trees/Animal Genes : TreeFamRAB18
Homologs : HomoloGeneRAB18
Homology/Alignments : Family Browser (UCSC)RAB18
Gene fusions - Rearrangements
Fusion : QuiverRAB18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB18
dbVarRAB18
ClinVarRAB18
MonarchRAB18
1000_GenomesRAB18 
Exome Variant ServerRAB18
GNOMAD BrowserENSG00000099246
Varsome BrowserRAB18
ACMGRAB18 variants
VarityQ9NP72
Genomic Variants (DGV)RAB18 [DGVbeta]
DECIPHERRAB18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB18 
Mutations
ICGC Data PortalRAB18 
TCGA Data PortalRAB18 
Broad Tumor PortalRAB18
OASIS PortalRAB18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB18  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRAB18
Mutations and Diseases : HGMDRAB18
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRAB18
DgiDB (Drug Gene Interaction Database)RAB18
DoCM (Curated mutations)RAB18
CIViC (Clinical Interpretations of Variants in Cancer)RAB18
Cancer3DRAB18
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602207    614222   
Orphanet2322   
DisGeNETRAB18
MedgenRAB18
Genetic Testing Registry RAB18
NextProtQ9NP72 [Medical]
GENETestsRAB18
Target ValidationRAB18
Huge Navigator RAB18 [HugePedia]
ClinGenRAB18
Clinical trials, drugs, therapy
MyCancerGenomeRAB18
Protein Interactions : CTDRAB18
Pharm GKB GenePA34106
PharosQ9NP72
Clinical trialRAB18
Miscellaneous
canSAR (ICR)RAB18
HarmonizomeRAB18
DataMed IndexRAB18
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRAB18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:27:45 CEST 2021
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