Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RAB1B (RAB1B, member RAS oncogene family)

Identity

Other alias-
HGNC (Hugo) RAB1B
LocusID (NCBI) 81876
Atlas_Id 41963
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66268585 and ends at 66277492 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EEF2 (19p13.3) / RAB1B (11q13.2)LAMB2 (3p21.31) / RAB1B (11q13.2)RAB1B (11q13.2) / MTMR2 (11q21)
RAB1B (11q13.2) / NFKBIZ (3q12.3)RAB1B (11q13.2) / SETD6 (16q21)RAB1B (11q13.2) / XBP1 (22q12.1)
SLC9A3R2 (16p13.3) / RAB1B (11q13.2)SOX7 (8p23.1) / RAB1B (11q13.2)TAMM41 (3p25.2) / RAB1B (11q13.2)
TTLL13P (15q26.1) / RAB1B (11q13.2)RAB1B 11q13.2 / MTMR2 11q21RAB1B 11q13.2 / XBP1 22q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB1B   18370
Cards
Entrez_Gene (NCBI)RAB1B  81876  RAB1B, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB1B
Ensembl hg19 (Hinxton)ENSG00000174903 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174903 [Gene_View]  chr11:66268585-66277492 [Contig_View]  RAB1B [Vega]
ICGC DataPortalENSG00000174903
TCGA cBioPortalRAB1B
AceView (NCBI)RAB1B
Genatlas (Paris)RAB1B
WikiGenes81876
SOURCE (Princeton)RAB1B
Genetics Home Reference (NIH)RAB1B
Genomic and cartography
GoldenPath hg38 (UCSC)RAB1B  -     chr11:66268585-66277492 +  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB1B  -     11q13.2   [Description]    (hg19-Feb_2009)
EnsemblRAB1B - 11q13.2 [CytoView hg19]  RAB1B - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIRAB1B [Mapview hg19]  RAB1B [Mapview hg38]
OMIM612565   
Gene and transcription
Genbank (Entrez)AF092437 AJ245875 AK292086 AK315333 AL136635
RefSeq transcript (Entrez)NM_030981
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB1B
Cluster EST : UnigeneHs.300816 [ NCBI ]
CGAP (NCI)Hs.300816
Alternative Splicing GalleryENSG00000174903
Gene ExpressionRAB1B [ NCBI-GEO ]   RAB1B [ EBI - ARRAY_EXPRESS ]   RAB1B [ SEEK ]   RAB1B [ MEM ]
Gene Expression Viewer (FireBrowse)RAB1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81876
GTEX Portal (Tissue expression)RAB1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0U4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0U4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0U4
Splice isoforms : SwissVarQ9H0U4
PhosPhoSitePlusQ9H0U4
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB1B
DMDM Disease mutations81876
Blocks (Seattle)RAB1B
PDB (SRS)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
PDB (PDBSum)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
PDB (IMB)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
PDB (RSDB)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
Structural Biology KnowledgeBase3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
SCOP (Structural Classification of Proteins)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
CATH (Classification of proteins structures)3JZA    3NKV    4HLQ    4I1O    5SZH    5SZK   
SuperfamilyQ9H0U4
Human Protein AtlasENSG00000174903
Peptide AtlasQ9H0U4
HPRD11469
IPIIPI00008964   IPI00022134   IPI01009517   IPI00975821   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0U4
IntAct (EBI)Q9H0U4
FunCoupENSG00000174903
BioGRIDRAB1B
STRING (EMBL)RAB1B
ZODIACRAB1B
Ontologies - Pathways
QuickGOQ9H0U4
Ontology : AmiGOGolgi membrane  Golgi membrane  GTPase activity  protein binding  GTP binding  mitochondrion  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  autophagy  protein transport  virion assembly  virion assembly  transport vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  pre-autophagosomal structure membrane  COPII vesicle coating  extracellular exosome  establishment of endothelial intestinal barrier  positive regulation of glycoprotein metabolic process  regulation of autophagosome assembly  
Ontology : EGO-EBIGolgi membrane  Golgi membrane  GTPase activity  protein binding  GTP binding  mitochondrion  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  autophagy  protein transport  virion assembly  virion assembly  transport vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  pre-autophagosomal structure membrane  COPII vesicle coating  extracellular exosome  establishment of endothelial intestinal barrier  positive regulation of glycoprotein metabolic process  regulation of autophagosome assembly  
Pathways : KEGGLegionellosis   
NDEx NetworkRAB1B
Atlas of Cancer Signalling NetworkRAB1B
Wikipedia pathwaysRAB1B
Orthology - Evolution
OrthoDB81876
GeneTree (enSembl)ENSG00000174903
Phylogenetic Trees/Animal Genes : TreeFamRAB1B
HOVERGENQ9H0U4
HOGENOMQ9H0U4
Homologs : HomoloGeneRAB1B
Homology/Alignments : Family Browser (UCSC)RAB1B
Gene fusions - Rearrangements
Fusion : MitelmanRAB1B/MTMR2 [11q13.2/11q21]  
Fusion : MitelmanRAB1B/XBP1 [11q13.2/22q12.1]  [t(11;22)(q13;q12)]  
Fusion: TCGARAB1B 11q13.2 MTMR2 11q21 LUAD
Fusion: TCGARAB1B 11q13.2 XBP1 22q12.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB1B
dbVarRAB1B
ClinVarRAB1B
1000_GenomesRAB1B 
Exome Variant ServerRAB1B
ExAC (Exome Aggregation Consortium)RAB1B (select the gene name)
Genetic variants : HAPMAP81876
Genomic Variants (DGV)RAB1B [DGVbeta]
DECIPHERRAB1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB1B 
Mutations
ICGC Data PortalRAB1B 
TCGA Data PortalRAB1B 
Broad Tumor PortalRAB1B
OASIS PortalRAB1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RAB1B
DgiDB (Drug Gene Interaction Database)RAB1B
DoCM (Curated mutations)RAB1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB1B (select a term)
intoGenRAB1B
Cancer3DRAB1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612565   
Orphanet
MedgenRAB1B
Genetic Testing Registry RAB1B
NextProtQ9H0U4 [Medical]
TSGene81876
GENETestsRAB1B
Target ValidationRAB1B
Huge Navigator RAB1B [HugePedia]
snp3D : Map Gene to Disease81876
BioCentury BCIQRAB1B
ClinGenRAB1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81876
Chemical/Pharm GKB GenePA34108
Clinical trialRAB1B
Miscellaneous
canSAR (ICR)RAB1B (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB1B
EVEXRAB1B
GoPubMedRAB1B
iHOPRAB1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:12:16 CEST 2017

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