RAB22A (RAB22A, member RAS oncogene family)

2003-02-01  

Identity

HGNC
LOCATION
20q13.32
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57403
MIM: 612966
HGNC: 9764
Ensembl: ENSG00000124209

Variants:

dbSNP: 57403
ClinVar: 57403
TCGA: ENSG00000124209
COSMIC: RAB22A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124209ENST00000244040Q9UL26

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
249387882014Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.118
151811552004Rab22a regulates the recycling of membrane proteins internalized independently of clathrin.97
252949012014miR-204-5p inhibits proliferation and invasion and enhances chemotherapeutic sensitivity of colorectal cancer cells by downregulating RAB22A.64
118702092002The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking.58
165379052006Rab22a regulates the sorting of transferrin to recycling endosomes.40
254604992014MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer.34
254298292015MicroRNA-204-5p inhibits gastric cancer cell proliferation by downregulating USP47 and RAB22A.33
197591772009Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.28
274848962016LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer.20
263826572015miR-203 Acts as a Tumor Suppressor Gene in Osteosarcoma by Regulating RAB22A.16

Citation

Dessen P

RAB22A (RAB22A, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41967/rab22a