Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RAB27A (RAB27A, member RAS oncogene family)

Identity

Other namesGS2
HsT18676
RAB27
RAM
HGNC (Hugo) RAB27A
LocusID (NCBI) 5873
Location 15q21.3
Location_base_pair Starts at 55495164 and ends at 55562592 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RAB27A   9766
Cards
Entrez_Gene (NCBI)RAB27A  5873  RAB27A, member RAS oncogene family
GeneCards (Weizmann)RAB27A
Ensembl (Hinxton)ENSG00000069974 [Gene_View]  chr15:55495164-55562592 [Contig_View]  RAB27A [Vega]
AceView (NCBI)RAB27A
Genatlas (Paris)RAB27A
WikiGenes5873
SOURCE (Princeton)NM_004580 NM_183234 NM_183235 NM_183236
Genomic and cartography
GoldenPath (UCSC)RAB27A  -  15q21.3   chr15:55495164-55562592 -  15q21.3   [Description]    (hg19-Feb_2009)
EnsemblRAB27A - 15q21.3 [CytoView]
Mapping of homologs : NCBIRAB27A [Mapview]
OMIM603868   607624   
Gene and transcription
Genbank (Entrez)AF125393 AF498953 AK312836 AV661679 BC107680
RefSeq transcript (Entrez)NM_004580 NM_183234 NM_183235 NM_183236
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NG_009103 NT_010194 NW_001838218 NW_004929398
Consensus coding sequences : CCDS (NCBI)RAB27A
Cluster EST : UnigeneHs.735555 [ NCBI ]
CGAP (NCI)Hs.735555
Alternative Splicing : Fast-db (Paris)GSHG0010438
Alternative Splicing GalleryENSG00000069974
Gene ExpressionRAB27A [ NCBI-GEO ]     RAB27A [ SEEK ]   RAB27A [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51159 (Uniprot)
NextProtP51159  [Medical]
With graphics : InterProP51159
Splice isoforms : SwissVarP51159 (Swissvar)
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Related proteins : CluSTrP51159
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAB (SM00175)  
DMDM Disease mutations5873
Blocks (Seattle)P51159
Human Protein AtlasENSG00000069974
Peptide AtlasP51159
HPRD04845
IPIIPI00016381   IPI00219858   
Protein Interaction databases
DIP (DOE-UCLA)P51159
IntAct (EBI)P51159
FunCoupENSG00000069974
BioGRIDRAB27A
InParanoidP51159
Interologous Interaction database P51159
IntegromeDBRAB27A
STRING (EMBL)RAB27A
Ontologies - Pathways
Ontology : AmiGOphotoreceptor outer segment  GTPase activity  protein binding  GTP binding  lysosome  late endosome  Golgi apparatus  protein targeting  exocytosis  small GTPase mediated signal transduction  blood coagulation  apical plasma membrane  GDP binding  protein domain specific binding  melanocyte differentiation  dendrite  secretory granule membrane  myosin V binding  melanosome transport  multivesicular body membrane  melanosome  cytotoxic T cell degranulation  natural killer cell degranulation  cellular protein metabolic process  positive regulation of exocytosis  exocytic vesicle  multivesicular body sorting pathway  
Ontology : EGO-EBIphotoreceptor outer segment  GTPase activity  protein binding  GTP binding  lysosome  late endosome  Golgi apparatus  protein targeting  exocytosis  small GTPase mediated signal transduction  blood coagulation  apical plasma membrane  GDP binding  protein domain specific binding  melanocyte differentiation  dendrite  secretory granule membrane  myosin V binding  melanosome transport  multivesicular body membrane  melanosome  cytotoxic T cell degranulation  natural killer cell degranulation  cellular protein metabolic process  positive regulation of exocytosis  exocytic vesicle  multivesicular body sorting pathway  
Pathways : BIOCARTARab GTPases Mark Targets In The Endocytotic Machinery [Genes]   
REACTOMERAB27A
Protein Interaction DatabaseRAB27A
Wikipedia pathwaysRAB27A
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RAB27A
SNP (GeneSNP Utah)RAB27A
SNP : HGBaseRAB27A
Genetic variants : HAPMAPRAB27A
1000_GenomesRAB27A 
ICGC programENSG00000069974 
Somatic Mutations in Cancer : COSMICRAB27A 
CONAN: Copy Number AnalysisRAB27A 
Mutations and Diseases : HGMDRAB27A
OMIM603868    607624   
GENETestsRAB27A
Disease Genetic AssociationRAB27A
Huge Navigator RAB27A [HugePedia]  RAB27A [HugeCancerGEM]
Genomic VariantsRAB27A  RAB27A [DGVbeta]
Exome VariantRAB27A
dbVarRAB27A
ClinVarRAB27A
snp3D : Map Gene to Disease5873
General knowledge
Homologs : HomoloGeneRAB27A
Homology/Alignments : Family Browser (UCSC)RAB27A
Phylogenetic Trees/Animal Genes : TreeFamRAB27A
Chemical/Protein Interactions : CTD5873
Chemical/Pharm GKB GenePA34117
Clinical trialRAB27A
Cancer Resource (Charite)ENSG00000069974
Other databases
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
CoreMineRAB27A
iHOPRAB27A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:44:36 CEST 2014

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