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RAB28 (RAB28, member RAS oncogene family)

Identity

Other aliasCORD18
HGNC (Hugo) RAB28
LocusID (NCBI) 9364
Atlas_Id 41974
Location 4p15.33  [Link to chromosome band 4p15]
Location_base_pair Starts at 13369347 and ends at 13485989 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RAB28 (4p15.33) / C14orf37 (14q23.1)RAB28 (4p15.33) / EXT1 (8q24.11)RAB28 (4p15.33) / MGME1 (20p11.23)
TBC1D1 (4p14) / RAB28 (4p15.33)RAB28 4p15.33 C20orf72TBC1D1 4p14 / RAB28 4p15.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB28   9768
Cards
Entrez_Gene (NCBI)RAB28  9364  RAB28, member RAS oncogene family
AliasesCORD18
GeneCards (Weizmann)RAB28
Ensembl hg19 (Hinxton)ENSG00000157869 [Gene_View]  chr4:13369347-13485989 [Contig_View]  RAB28 [Vega]
Ensembl hg38 (Hinxton)ENSG00000157869 [Gene_View]  chr4:13369347-13485989 [Contig_View]  RAB28 [Vega]
ICGC DataPortalENSG00000157869
TCGA cBioPortalRAB28
AceView (NCBI)RAB28
Genatlas (Paris)RAB28
WikiGenes9364
SOURCE (Princeton)RAB28
Genetics Home Reference (NIH)RAB28
Genomic and cartography
GoldenPath hg19 (UCSC)RAB28  -     chr4:13369347-13485989 -  4p15.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RAB28  -     4p15.33   [Description]    (hg38-Dec_2013)
EnsemblRAB28 - 4p15.33 [CytoView hg19]  RAB28 - 4p15.33 [CytoView hg38]
Mapping of homologs : NCBIRAB28 [Mapview hg19]  RAB28 [Mapview hg38]
OMIM612994   615374   
Gene and transcription
Genbank (Entrez)AF498955 AK027027 BC018067 BC035054 BQ021120
RefSeq transcript (Entrez)NM_001017979 NM_001159601 NM_004249
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_033891 NT_006316 NW_004929315
Consensus coding sequences : CCDS (NCBI)RAB28
Cluster EST : UnigeneHs.677409 [ NCBI ]
CGAP (NCI)Hs.677409
Alternative Splicing GalleryENSG00000157869
Gene ExpressionRAB28 [ NCBI-GEO ]   RAB28 [ EBI - ARRAY_EXPRESS ]   RAB28 [ SEEK ]   RAB28 [ MEM ]
Gene Expression Viewer (FireBrowse)RAB28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9364
GTEX Portal (Tissue expression)RAB28
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51157   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51157  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51157
Splice isoforms : SwissVarP51157
PhosPhoSitePlusP51157
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB28
DMDM Disease mutations9364
Blocks (Seattle)RAB28
PDB (SRS)2HXS    3E5H   
PDB (PDBSum)2HXS    3E5H   
PDB (IMB)2HXS    3E5H   
PDB (RSDB)2HXS    3E5H   
Structural Biology KnowledgeBase2HXS    3E5H   
SCOP (Structural Classification of Proteins)2HXS    3E5H   
CATH (Classification of proteins structures)2HXS    3E5H   
SuperfamilyP51157
Human Protein AtlasENSG00000157869
Peptide AtlasP51157
HPRD06699
IPIIPI00016377   IPI00219679   IPI00929378   IPI00967565   IPI00967257   IPI00968073   
Protein Interaction databases
DIP (DOE-UCLA)P51157
IntAct (EBI)P51157
FunCoupENSG00000157869
BioGRIDRAB28
STRING (EMBL)RAB28
ZODIACRAB28
Ontologies - Pathways
QuickGOP51157
Ontology : AmiGOGTPase activity  GTP binding  cytoplasm  plasma membrane  intracellular protein transport  nucleocytoplasmic transport  small GTPase mediated signal transduction  metabolic process  GDP binding  ciliary rootlet  ciliary basal body  toxin transport  
Ontology : EGO-EBIGTPase activity  GTP binding  cytoplasm  plasma membrane  intracellular protein transport  nucleocytoplasmic transport  small GTPase mediated signal transduction  metabolic process  GDP binding  ciliary rootlet  ciliary basal body  toxin transport  
NDEx NetworkRAB28
Atlas of Cancer Signalling NetworkRAB28
Wikipedia pathwaysRAB28
Orthology - Evolution
OrthoDB9364
GeneTree (enSembl)ENSG00000157869
Phylogenetic Trees/Animal Genes : TreeFamRAB28
HOVERGENP51157
HOGENOMP51157
Homologs : HomoloGeneRAB28
Homology/Alignments : Family Browser (UCSC)RAB28
Gene fusions - Rearrangements
Fusion : MitelmanRAB28/MGME1 [4p15.33/20p11.23]  
Fusion : MitelmanTBC1D1/RAB28 [4p14/4p15.33]  [t(4;4)(p14;p15)]  
Fusion: TCGARAB28 4p15.33 C20orf72 BRCA
Fusion: TCGATBC1D1 4p14 RAB28 4p15.33 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB28
dbVarRAB28
ClinVarRAB28
1000_GenomesRAB28 
Exome Variant ServerRAB28
ExAC (Exome Aggregation Consortium)RAB28 (select the gene name)
Genetic variants : HAPMAP9364
Genomic Variants (DGV)RAB28 [DGVbeta]
DECIPHER (Syndromes)4:13369347-13485989  ENSG00000157869
CONAN: Copy Number AnalysisRAB28 
Mutations
ICGC Data PortalRAB28 
TCGA Data PortalRAB28 
Broad Tumor PortalRAB28
OASIS PortalRAB28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAB28
DgiDB (Drug Gene Interaction Database)RAB28
DoCM (Curated mutations)RAB28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB28 (select a term)
intoGenRAB28
Cancer3DRAB28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612994    615374   
Orphanet1843   
MedgenRAB28
Genetic Testing Registry RAB28
NextProtP51157 [Medical]
TSGene9364
GENETestsRAB28
Huge Navigator RAB28 [HugePedia]
snp3D : Map Gene to Disease9364
BioCentury BCIQRAB28
ClinGenRAB28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9364
Chemical/Pharm GKB GenePA34119
Clinical trialRAB28
Miscellaneous
canSAR (ICR)RAB28 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB28
EVEXRAB28
GoPubMedRAB28
iHOPRAB28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:23:55 CET 2017

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