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RAB2B (RAB2B, member RAS oncogene family)

Identity

Alias_symbol (synonym)FLJ14824
Other alias-
HGNC (Hugo) RAB2B
LocusID (NCBI) 84932
Atlas_Id 41975
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 21459020 and ends at 21476673 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHD8 (14q11.2) / RAB2B (14q11.2)CHD8 14q11.2 / RAB2B 14q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB2B   20246
Cards
Entrez_Gene (NCBI)RAB2B  84932  RAB2B, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB2B
Ensembl hg19 (Hinxton)ENSG00000129472 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129472 [Gene_View]  chr14:21459020-21476673 [Contig_View]  RAB2B [Vega]
ICGC DataPortalENSG00000129472
TCGA cBioPortalRAB2B
AceView (NCBI)RAB2B
Genatlas (Paris)RAB2B
WikiGenes84932
SOURCE (Princeton)RAB2B
Genetics Home Reference (NIH)RAB2B
Genomic and cartography
GoldenPath hg38 (UCSC)RAB2B  -     chr14:21459020-21476673 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB2B  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblRAB2B - 14q11.2 [CytoView hg19]  RAB2B - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIRAB2B [Mapview hg19]  RAB2B [Mapview hg38]
OMIM607466   
Gene and transcription
Genbank (Entrez)AF091029 AF468652 AK027730 AK296057 AK300599
RefSeq transcript (Entrez)NM_001163380 NM_032846
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB2B
Cluster EST : UnigeneHs.22399 [ NCBI ]
CGAP (NCI)Hs.22399
Alternative Splicing GalleryENSG00000129472
Gene ExpressionRAB2B [ NCBI-GEO ]   RAB2B [ EBI - ARRAY_EXPRESS ]   RAB2B [ SEEK ]   RAB2B [ MEM ]
Gene Expression Viewer (FireBrowse)RAB2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84932
GTEX Portal (Tissue expression)RAB2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUD1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUD1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUD1
Splice isoforms : SwissVarQ8WUD1
PhosPhoSitePlusQ8WUD1
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB2B
DMDM Disease mutations84932
Blocks (Seattle)RAB2B
PDB (SRS)2A5J   
PDB (PDBSum)2A5J   
PDB (IMB)2A5J   
PDB (RSDB)2A5J   
Structural Biology KnowledgeBase2A5J   
SCOP (Structural Classification of Proteins)2A5J   
CATH (Classification of proteins structures)2A5J   
SuperfamilyQ8WUD1
Human Protein AtlasENSG00000129472
Peptide AtlasQ8WUD1
HPRD06312
IPIIPI00102896   IPI00879279   IPI00433806   IPI00064352   IPI00943589   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUD1
IntAct (EBI)Q8WUD1
FunCoupENSG00000129472
BioGRIDRAB2B
STRING (EMBL)RAB2B
ZODIACRAB2B
Ontologies - Pathways
QuickGOQ8WUD1
Ontology : AmiGOGolgi membrane  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  plasma membrane  protein transport  vesicle-mediated transport  positive regulation of exocytosis  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  plasma membrane  protein transport  vesicle-mediated transport  positive regulation of exocytosis  extracellular exosome  
NDEx NetworkRAB2B
Atlas of Cancer Signalling NetworkRAB2B
Wikipedia pathwaysRAB2B
Orthology - Evolution
OrthoDB84932
GeneTree (enSembl)ENSG00000129472
Phylogenetic Trees/Animal Genes : TreeFamRAB2B
HOVERGENQ8WUD1
HOGENOMQ8WUD1
Homologs : HomoloGeneRAB2B
Homology/Alignments : Family Browser (UCSC)RAB2B
Gene fusions - Rearrangements
Fusion : MitelmanCHD8/RAB2B [14q11.2/14q11.2]  [t(14;14)(q11;q11)]  
Fusion: TCGACHD8 14q11.2 RAB2B 14q11.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB2B
dbVarRAB2B
ClinVarRAB2B
1000_GenomesRAB2B 
Exome Variant ServerRAB2B
ExAC (Exome Aggregation Consortium)RAB2B (select the gene name)
Genetic variants : HAPMAP84932
Genomic Variants (DGV)RAB2B [DGVbeta]
DECIPHERRAB2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB2B 
Mutations
ICGC Data PortalRAB2B 
TCGA Data PortalRAB2B 
Broad Tumor PortalRAB2B
OASIS PortalRAB2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAB2B
DgiDB (Drug Gene Interaction Database)RAB2B
DoCM (Curated mutations)RAB2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB2B (select a term)
intoGenRAB2B
Cancer3DRAB2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607466   
Orphanet
MedgenRAB2B
Genetic Testing Registry RAB2B
NextProtQ8WUD1 [Medical]
TSGene84932
GENETestsRAB2B
Target ValidationRAB2B
Huge Navigator RAB2B [HugePedia]
snp3D : Map Gene to Disease84932
BioCentury BCIQRAB2B
ClinGenRAB2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84932
Chemical/Pharm GKB GenePA134865942
Clinical trialRAB2B
Miscellaneous
canSAR (ICR)RAB2B (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB2B
EVEXRAB2B
GoPubMedRAB2B
iHOPRAB2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:12:18 CEST 2017

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