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RAB3A (RAB3A, member RAS oncogene family)

Identity

Other alias-
HGNC (Hugo) RAB3A
LocusID (NCBI) 5864
Atlas_Id 41989
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 18196801 and ends at 18204064 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB3A   9777
Cards
Entrez_Gene (NCBI)RAB3A  5864  RAB3A, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB3A
Ensembl hg19 (Hinxton)ENSG00000105649 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105649 [Gene_View]  chr19:18196801-18204064 [Contig_View]  RAB3A [Vega]
ICGC DataPortalENSG00000105649
TCGA cBioPortalRAB3A
AceView (NCBI)RAB3A
Genatlas (Paris)RAB3A
WikiGenes5864
SOURCE (Princeton)RAB3A
Genetics Home Reference (NIH)RAB3A
Genomic and cartography
GoldenPath hg38 (UCSC)RAB3A  -     chr19:18196801-18204064 -  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB3A  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblRAB3A - 19p13.11 [CytoView hg19]  RAB3A - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIRAB3A [Mapview hg19]  RAB3A [Mapview hg38]
OMIM179490   
Gene and transcription
Genbank (Entrez)AF254795 AF498931 AK289559 AK293467 BC011782
RefSeq transcript (Entrez)NM_002866
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB3A
Cluster EST : UnigeneHs.27744 [ NCBI ]
CGAP (NCI)Hs.27744
Alternative Splicing GalleryENSG00000105649
Gene ExpressionRAB3A [ NCBI-GEO ]   RAB3A [ EBI - ARRAY_EXPRESS ]   RAB3A [ SEEK ]   RAB3A [ MEM ]
Gene Expression Viewer (FireBrowse)RAB3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5864
GTEX Portal (Tissue expression)RAB3A
Human Protein AtlasENSG00000105649-RAB3A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20336   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20336  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20336
Splice isoforms : SwissVarP20336
PhosPhoSitePlusP20336
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB3A
DMDM Disease mutations5864
Blocks (Seattle)RAB3A
SuperfamilyP20336
Human Protein Atlas [tissue]ENSG00000105649-RAB3A [tissue]
Peptide AtlasP20336
HPRD01535
IPIIPI00023504   
Protein Interaction databases
DIP (DOE-UCLA)P20336
IntAct (EBI)P20336
FunCoupENSG00000105649
BioGRIDRAB3A
STRING (EMBL)RAB3A
ZODIACRAB3A
Ontologies - Pathways
QuickGOP20336
Ontology : AmiGOacrosomal vesicle  ATPase activator activity  respiratory system process  GTPase activity  GTPase activity  protein binding  GTP binding  endosome  cytosol  plasma membrane  mitochondrion organization  neurotransmitter secretion  neuromuscular synaptic transmission  axonogenesis  synaptic vesicle  protein C-terminus binding  post-embryonic development  glutamate secretion  protein transport  synaptic vesicle exocytosis  synaptic vesicle maturation  lung development  axon  secretory granule membrane  GTP-dependent protein binding  myosin V binding  regulation of synaptic vesicle fusion to presynaptic active zone membrane  positive regulation of ATPase activity  synaptic vesicle recycling  terminal bouton  protein complex  neutrophil degranulation  constitutive secretory pathway  positive regulation of exocytosis  regulation of short-term neuronal synaptic plasticity  maintenance of presynaptic active zone structure  sensory perception of touch  ATPase binding  response to electrical stimulus  clathrin-sculpted acetylcholine transport vesicle membrane  clathrin-sculpted glutamate transport vesicle membrane  membrane organization  clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane  evoked neurotransmitter secretion  clathrin-sculpted monoamine transport vesicle membrane  anchored component of synaptic vesicle membrane  positive regulation of regulated secretory pathway  extracellular vesicle  
Ontology : EGO-EBIacrosomal vesicle  ATPase activator activity  respiratory system process  GTPase activity  GTPase activity  protein binding  GTP binding  endosome  cytosol  plasma membrane  mitochondrion organization  neurotransmitter secretion  neuromuscular synaptic transmission  axonogenesis  synaptic vesicle  protein C-terminus binding  post-embryonic development  glutamate secretion  protein transport  synaptic vesicle exocytosis  synaptic vesicle maturation  lung development  axon  secretory granule membrane  GTP-dependent protein binding  myosin V binding  regulation of synaptic vesicle fusion to presynaptic active zone membrane  positive regulation of ATPase activity  synaptic vesicle recycling  terminal bouton  protein complex  neutrophil degranulation  constitutive secretory pathway  positive regulation of exocytosis  regulation of short-term neuronal synaptic plasticity  maintenance of presynaptic active zone structure  sensory perception of touch  ATPase binding  response to electrical stimulus  clathrin-sculpted acetylcholine transport vesicle membrane  clathrin-sculpted glutamate transport vesicle membrane  membrane organization  clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane  evoked neurotransmitter secretion  clathrin-sculpted monoamine transport vesicle membrane  anchored component of synaptic vesicle membrane  positive regulation of regulated secretory pathway  extracellular vesicle  
Pathways : BIOCARTARab GTPases Mark Targets In The Endocytotic Machinery [Genes]   
Pathways : KEGGSynaptic vesicle cycle    Insulin secretion   
NDEx NetworkRAB3A
Atlas of Cancer Signalling NetworkRAB3A
Wikipedia pathwaysRAB3A
Orthology - Evolution
OrthoDB5864
GeneTree (enSembl)ENSG00000105649
Phylogenetic Trees/Animal Genes : TreeFamRAB3A
HOVERGENP20336
HOGENOMP20336
Homologs : HomoloGeneRAB3A
Homology/Alignments : Family Browser (UCSC)RAB3A
Gene fusions - Rearrangements
Tumor Fusion PortalRAB3A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB3A
dbVarRAB3A
ClinVarRAB3A
1000_GenomesRAB3A 
Exome Variant ServerRAB3A
ExAC (Exome Aggregation Consortium)ENSG00000105649
GNOMAD BrowserENSG00000105649
Genetic variants : HAPMAP5864
Genomic Variants (DGV)RAB3A [DGVbeta]
DECIPHERRAB3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB3A 
Mutations
ICGC Data PortalRAB3A 
TCGA Data PortalRAB3A 
Broad Tumor PortalRAB3A
OASIS PortalRAB3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAB3A
DgiDB (Drug Gene Interaction Database)RAB3A
DoCM (Curated mutations)RAB3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB3A (select a term)
intoGenRAB3A
Cancer3DRAB3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM179490   
Orphanet
DisGeNETRAB3A
MedgenRAB3A
Genetic Testing Registry RAB3A
NextProtP20336 [Medical]
TSGene5864
GENETestsRAB3A
Target ValidationRAB3A
Huge Navigator RAB3A [HugePedia]
snp3D : Map Gene to Disease5864
BioCentury BCIQRAB3A
ClinGenRAB3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5864
Chemical/Pharm GKB GenePA34132
Clinical trialRAB3A
Miscellaneous
canSAR (ICR)RAB3A (select the gene name)
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB3A
EVEXRAB3A
GoPubMedRAB3A
iHOPRAB3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:31:22 CET 2017

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