RAB40B (RAB40B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
RAR,SEC4L
FUSION GENES

Other Information

Locus ID:

NCBI: 10966
HGNC: 18284
Ensembl: ENSG00000141542

Variants:

dbSNP: 10966
ClinVar: 10966
TCGA: ENSG00000141542
COSMIC: RAB40B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141542ENST00000269347J3KN64
ENSG00000141542ENST00000538809H0YFJ5
ENSG00000141542ENST00000571995Q12829
ENSG00000141542ENST00000576148I3L178

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

References

Pubmed IDYearTitleCitations
239026852013Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells.55
277895762016The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion.15
257907802015Rab40b upregulation correlates with the prognosis of gastric cancer by promoting migration, invasion, and metastasis.6
279090762016Rab40b and Tks5 interact at invadopodia during metastasis.0

Citation

Dessen P

RAB40B (RAB40B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41995/rab40b