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RAB4B (RAB4B, member RAS oncogene family)

Identity

Alias (NCBI)-
HGNC (Hugo) RAB4B
HGNC Alias symbFLJ78649
MGC52123
HGNC Alias nameras-related GTP-binding protein 4b
 small GTP binding protein RAB4B
LocusID (NCBI) 53916
Atlas_Id 42000
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 40778247 and ends at 40796942 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LMNA (1q22) / RAB4B (19q13.2)LMNA 1q22 / RAB4B 19q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RAB4B   9782
Cards
Entrez_Gene (NCBI)RAB4B    RAB4B, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB4B
Ensembl hg19 (Hinxton)ENSG00000167578 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167578 [Gene_View]  ENSG00000167578 [Sequence]  chr19:40778247-40796942 [Contig_View]  RAB4B [Vega]
ICGC DataPortalENSG00000167578
TCGA cBioPortalRAB4B
AceView (NCBI)RAB4B
Genatlas (Paris)RAB4B
SOURCE (Princeton)RAB4B
Genetics Home Reference (NIH)RAB4B
Genomic and cartography
GoldenPath hg38 (UCSC)RAB4B  -     chr19:40778247-40796942 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB4B  -     19q13.2   [Description]    (hg19-Feb_2009)
GoldenPathRAB4B - 19q13.2 [CytoView hg19]  RAB4B - 19q13.2 [CytoView hg38]
ImmunoBaseENSG00000167578
Genome Data Viewer NCBIRAB4B [Mapview hg19]  
OMIM612945   
Gene and transcription
Genbank (Entrez)AF165522 AF217985 AF498935 AI083750 AK024845
RefSeq transcript (Entrez)NM_016154
Consensus coding sequences : CCDS (NCBI)RAB4B
Gene ExpressionRAB4B [ NCBI-GEO ]   RAB4B [ EBI - ARRAY_EXPRESS ]   RAB4B [ SEEK ]   RAB4B [ MEM ]
Gene Expression Viewer (FireBrowse)RAB4B [ Firebrowse - Broad ]
GenevisibleExpression of RAB4B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53916
GTEX Portal (Tissue expression)RAB4B
Human Protein AtlasENSG00000167578-RAB4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61018   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61018  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61018
PhosPhoSitePlusP61018
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Rab4    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB4B
PDB (RSDB)2O52   
PDB Europe2O52   
PDB (PDBSum)2O52   
PDB (IMB)2O52   
Structural Biology KnowledgeBase2O52   
SCOP (Structural Classification of Proteins)2O52   
CATH (Classification of proteins structures)2O52   
SuperfamilyP61018
AlphaFold pdb e-kbP61018   
Human Protein Atlas [tissue]ENSG00000167578-RAB4B [tissue]
HPRD11473
Protein Interaction databases
DIP (DOE-UCLA)P61018
IntAct (EBI)P61018
BioGRIDRAB4B
STRING (EMBL)RAB4B
ZODIACRAB4B
Ontologies - Pathways
QuickGOP61018
Ontology : AmiGOmolecular_function  G protein activity  protein binding  GTP binding  endosome  plasma membrane  protein transport  regulation of endocytosis  secretory granule membrane  Rab protein signal transduction  insulin-responsive compartment  insulin-responsive compartment  neutrophil degranulation  glucose import  perinuclear region of cytoplasm  recycling endosome  
Ontology : EGO-EBImolecular_function  G protein activity  protein binding  GTP binding  endosome  plasma membrane  protein transport  regulation of endocytosis  secretory granule membrane  Rab protein signal transduction  insulin-responsive compartment  insulin-responsive compartment  neutrophil degranulation  glucose import  perinuclear region of cytoplasm  recycling endosome  
NDEx NetworkRAB4B
Atlas of Cancer Signalling NetworkRAB4B
Wikipedia pathwaysRAB4B
Orthology - Evolution
OrthoDB53916
GeneTree (enSembl)ENSG00000167578
Phylogenetic Trees/Animal Genes : TreeFamRAB4B
Homologs : HomoloGeneRAB4B
Homology/Alignments : Family Browser (UCSC)RAB4B
Gene fusions - Rearrangements
Fusion : MitelmanLMNA/RAB4B [1q22/19q13.2]  
Fusion : QuiverRAB4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB4B
dbVarRAB4B
ClinVarRAB4B
MonarchRAB4B
1000_GenomesRAB4B 
Exome Variant ServerRAB4B
GNOMAD BrowserENSG00000167578
Varsome BrowserRAB4B
ACMGRAB4B variants
VarityP61018
Genomic Variants (DGV)RAB4B [DGVbeta]
DECIPHERRAB4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB4B 
Mutations
ICGC Data PortalRAB4B 
TCGA Data PortalRAB4B 
Broad Tumor PortalRAB4B
OASIS PortalRAB4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB4B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRAB4B
Mutations and Diseases : HGMDRAB4B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRAB4B
DgiDB (Drug Gene Interaction Database)RAB4B
DoCM (Curated mutations)RAB4B
CIViC (Clinical Interpretations of Variants in Cancer)RAB4B
Cancer3DRAB4B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612945   
Orphanet
DisGeNETRAB4B
MedgenRAB4B
Genetic Testing Registry RAB4B
NextProtP61018 [Medical]
GENETestsRAB4B
Target ValidationRAB4B
Huge Navigator RAB4B [HugePedia]
ClinGenRAB4B
Clinical trials, drugs, therapy
MyCancerGenomeRAB4B
Protein Interactions : CTDRAB4B
Pharm GKB GenePA34142
PharosP61018
Clinical trialRAB4B
Miscellaneous
canSAR (ICR)RAB4B
HarmonizomeRAB4B
DataMed IndexRAB4B
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRAB4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:27:56 CEST 2021

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