RAB4B (RAB4B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 53916
MIM: 612945
HGNC: 9782
Ensembl: ENSG00000167578

Variants:

dbSNP: 53916
ClinVar: 53916
TCGA: ENSG00000167578
COSMIC: RAB4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167578ENST00000357052P61018
ENSG00000167578ENST00000357052A0A024R0K8
ENSG00000167578ENST00000378307Q6PIK3
ENSG00000167578ENST00000594800P61018
ENSG00000167578ENST00000594800A0A024R0K8
ENSG00000167578ENST00000602173M0R0X1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Neutrophil degranulationREACTOMER-HSA-6798695
Signaling by METREACTOMER-HSA-6806834
MET receptor recyclingREACTOMER-HSA-8875656
RAB geranylgeranylationREACTOMER-HSA-8873719

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
195907522009Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.13
240062552013Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1.5
283067192017Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.4
305668602018Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.4
299460452018Identification of Host Factors Involved in Human Cytomegalovirus Replication, Assembly, and Egress Using a Two-Step Small Interfering RNA Screen.2

Citation

Dessen P

RAB4B (RAB4B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42000/rab4b