RAB6C (RAB6C, member RAS oncogene family)

2003-12-01  

Identity

HGNC
RAB6C
LOCATION
2q21.1
LOCUSID
84084
ALIAS
WTH3

Other Information

Locus ID:

NCBI: 84084
MIM: 612909
HGNC: 16525
Ensembl: ENSG00000222014

Variants:

dbSNP: 84084
ClinVar: 84084
TCGA: ENSG00000222014
COSMIC: RAB6C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000222014ENST00000410061Q9H0N0

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
200645282010RAB6C is a retrogene that encodes a centrosomal protein involved in cell cycle progression.28
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
282558132017Gene promoter-associated CpG island hypermethylation in squamous cell carcinoma of the tongue.9
174267082007WTH3 is a direct target of the p53 protein.7
189921512008Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression.7
162670282005Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells.6
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
229491992012Crystallization and preliminary X-ray crystallographic studies of Rab6A'(Q72L): a GTP-locked form.1

Citation

Dessen P

RAB6C (RAB6C, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/53309/rab6c