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RAB7B (RAB7B, member RAS oncogene family)

Identity

Alias_symbol (synonym)MGC9726
MGC16212
Other aliasRAB7
HGNC (Hugo) RAB7B
LocusID (NCBI) 338382
Atlas_Id 41357
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 205976740 and ends at 206003466 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB7B   30513
Cards
Entrez_Gene (NCBI)RAB7B  338382  RAB7B, member RAS oncogene family
AliasesRAB7
GeneCards (Weizmann)RAB7B
Ensembl hg19 (Hinxton)ENSG00000276600 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000276600 [Gene_View]  chr1:205976740-206003466 [Contig_View]  RAB7B [Vega]
ICGC DataPortalENSG00000276600
TCGA cBioPortalRAB7B
AceView (NCBI)RAB7B
Genatlas (Paris)RAB7B
WikiGenes338382
SOURCE (Princeton)RAB7B
Genetics Home Reference (NIH)RAB7B
Genomic and cartography
GoldenPath hg38 (UCSC)RAB7B  -     chr1:205976740-206003466 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB7B  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblRAB7B - 1q32.1 [CytoView hg19]  RAB7B - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIRAB7B [Mapview hg19]  RAB7B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI264357 AK122657 AK127140 AY094596 BC007382
RefSeq transcript (Entrez)NM_001164522 NM_001304839 NM_177403
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB7B
Cluster EST : UnigeneHs.534612 [ NCBI ]
CGAP (NCI)Hs.534612
Alternative Splicing GalleryENSG00000276600
Gene ExpressionRAB7B [ NCBI-GEO ]   RAB7B [ EBI - ARRAY_EXPRESS ]   RAB7B [ SEEK ]   RAB7B [ MEM ]
Gene Expression Viewer (FireBrowse)RAB7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338382
GTEX Portal (Tissue expression)RAB7B
Human Protein AtlasENSG00000276600-RAB7B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AH8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AH8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AH8
Splice isoforms : SwissVarQ96AH8
PhosPhoSitePlusQ96AH8
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB7B
DMDM Disease mutations338382
Blocks (Seattle)RAB7B
SuperfamilyQ96AH8
Human Protein Atlas [tissue]ENSG00000276600-RAB7B [tissue]
Peptide AtlasQ96AH8
HPRD15202
IPIIPI00059444   
Protein Interaction databases
DIP (DOE-UCLA)Q96AH8
IntAct (EBI)Q96AH8
FunCoupENSG00000276600
BioGRIDRAB7B
STRING (EMBL)RAB7B
ZODIACRAB7B
Ontologies - Pathways
QuickGOQ96AH8
Ontology : AmiGOGTPase activity  GTP binding  lysosome  late endosome  Golgi apparatus  trans-Golgi network  protein transport  phagocytic vesicle membrane  late endosome membrane  positive regulation of interleukin-6 production  negative regulation of toll-like receptor 4 signaling pathway  negative regulation of toll-like receptor 9 signaling pathway  late endosome to Golgi transport  phagocytic vesicle  positive regulation of megakaryocyte differentiation  positive regulation of NF-kappaB transcription factor activity  membrane organization  
Ontology : EGO-EBIGTPase activity  GTP binding  lysosome  late endosome  Golgi apparatus  trans-Golgi network  protein transport  phagocytic vesicle membrane  late endosome membrane  positive regulation of interleukin-6 production  negative regulation of toll-like receptor 4 signaling pathway  negative regulation of toll-like receptor 9 signaling pathway  late endosome to Golgi transport  phagocytic vesicle  positive regulation of megakaryocyte differentiation  positive regulation of NF-kappaB transcription factor activity  membrane organization  
Pathways : KEGGPhagosome    Salmonella infection    Amoebiasis   
NDEx NetworkRAB7B
Atlas of Cancer Signalling NetworkRAB7B
Wikipedia pathwaysRAB7B
Orthology - Evolution
OrthoDB338382
GeneTree (enSembl)ENSG00000276600
Phylogenetic Trees/Animal Genes : TreeFamRAB7B
HOVERGENQ96AH8
HOGENOMQ96AH8
Homologs : HomoloGeneRAB7B
Homology/Alignments : Family Browser (UCSC)RAB7B
Gene fusions - Rearrangements
Tumor Fusion PortalRAB7B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB7B
dbVarRAB7B
ClinVarRAB7B
1000_GenomesRAB7B 
Exome Variant ServerRAB7B
ExAC (Exome Aggregation Consortium)ENSG00000276600
GNOMAD BrowserENSG00000276600
Genetic variants : HAPMAP338382
Genomic Variants (DGV)RAB7B [DGVbeta]
DECIPHERRAB7B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB7B 
Mutations
ICGC Data PortalRAB7B 
TCGA Data PortalRAB7B 
Broad Tumor PortalRAB7B
OASIS PortalRAB7B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDRAB7B
BioMutasearch RAB7B
DgiDB (Drug Gene Interaction Database)RAB7B
DoCM (Curated mutations)RAB7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB7B (select a term)
intoGenRAB7B
Cancer3DRAB7B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRAB7B
MedgenRAB7B
Genetic Testing Registry RAB7B
NextProtQ96AH8 [Medical]
TSGene338382
GENETestsRAB7B
Target ValidationRAB7B
Huge Navigator RAB7B [HugePedia]
snp3D : Map Gene to Disease338382
BioCentury BCIQRAB7B
ClinGenRAB7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338382
Chemical/Pharm GKB GenePA134940117
Clinical trialRAB7B
Miscellaneous
canSAR (ICR)RAB7B (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB7B
EVEXRAB7B
GoPubMedRAB7B
iHOPRAB7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:31:27 CET 2017

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