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RAB8A (RAB8A, member RAS oncogene family)

Identity

Other namesMEL
RAB8
HGNC (Hugo) RAB8A
LocusID (NCBI) 4218
Location 19p13.12
Location_base_pair Starts at 16222490 and ends at 16244445 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RAB8A   7007
Entrez_Gene (NCBI)RAB8A  4218  RAB8A, member RAS oncogene family
Cards
GeneCards (Weizmann)RAB8A
Ensembl (Hinxton)ENSG00000167461 [Gene_View]  chr19:16222490-16244445 [Contig_View]  RAB8A [Vega]
AceView (NCBI)RAB8A
Genatlas (Paris)RAB8A
SOURCE (Stanford)NM_005370
Genomic and cartography
GoldenPath (UCSC)RAB8A  -  19p13.12   chr19:16222490-16244445 +  19p13.12   [Description]    (hg19-Feb_2009)
EnsemblRAB8A - 19p13.12 [CytoView]
Mapping of homologs : NCBIRAB8A [Mapview]
OMIM165040   
Gene and transcription
Genbank (Entrez)AB209767 AF498943 AK025165 AK293676 BC002977
RefSeq transcript (SRS)NM_005370
RefSeq transcript (Entrez)NM_005370
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NT_011295 NW_001838484 NW_004078098
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011295 NW_001838484 NW_004078098
Consensus coding sequences : CCDS (NCBI)RAB8A
Cluster EST : UnigeneHs.642874 [ SRS ] Hs.642874 [ NCBI ]
CGAP (NCI)Hs.642874
Alternative Splicing : Fast-db (Paris)GSHG0033328
Alternative Splicing GalleryENSG00000167461
Gene ExpressionRAB8A [ NCBI-GEO ]   RAB8A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61006 (SRS) P61006 (Uniprot)
NextProtP61006
With graphics : InterProP61006
Splice isoforms : SwissVarP61006(Swissvar)
Domaine pattern : Prosite (SRS)RAB (PS51419)   
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (SRS)Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Domains : Interpro (EBI)Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Related proteins : CluSTrP61006
Domain families : Pfam (SRS)Ras (PF00071)   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAB (SM00175)  
DMDM4218
Blocks (Seattle)P61006
PDB (SRS)3QBT    3TNF   
PDB (PDBSum)3QBT    3TNF   
PDB (IMB)3QBT    3TNF   
PDB (RSDB)3QBT    3TNF   
Human Protein AtlasENSG00000167461
HPRD01296
IPIIPI00028481   IPI00556414   
Protein Interaction databases
DIP (DOE-UCLA)P61006
IntAct (EBI)P61006
FunCoupENSG00000167461
REACTOMERAB8A
Protein Interaction Database4218
BioGRIDRAB8A
InParanoidP61006
Interologous Interaction database P61006
IntegromeDBRAB8A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RAB8A
SNP (GeneSNP Utah)RAB8A
SNP : HGBaseRAB8A
Genetic variants : HAPMAPRAB8A
Somatic Mutations in Cancer : COSMICRAB8A 
CONAN: Copy Number AnalysisRAB8A 
Mutations and Diseases : HGMDRAB8A
OMIM165040   
GENETests165040   
Disease Genetic AssociationRAB8A
Huge Navigator RAB8A [HugePedia]  RAB8A [HugeCancerGEM]
Genomic VariantsRAB8A  RAB8A [DGVbeta]
snp3D : Map Gene to Disease4218
General knowledge
Homologs : HomoloGeneRAB8A
Homology/Alignments : Family Browser (UCSC)RAB8A
Phylogenetic Trees/Animal Genes : TreeFamRAB8A
Chemical/Protein Interactions : CTD4218
Chemical/Pharm GKB GenePA30743
Clinical trialRAB8A
Cancer Resource (Charite)ENSG00000167461
Ontology : AmiGOprotein binding  GTP binding  Golgi apparatus  plasma membrane  microtubule basal body  vesicle docking involved in exocytosis  small GTPase mediated signal transduction  axonogenesis  protein transport  Rab GTPase binding  GDP binding  nonmotile primary cilium  cilium assembly  phagocytic vesicle  Golgi vesicle fusion to target membrane  perinuclear region of cytoplasm  recycling endosome  
Ontology : EGO-EBIprotein binding  GTP binding  Golgi apparatus  plasma membrane  microtubule basal body  vesicle docking involved in exocytosis  small GTPase mediated signal transduction  axonogenesis  protein transport  Rab GTPase binding  GDP binding  nonmotile primary cilium  cilium assembly  phagocytic vesicle  Golgi vesicle fusion to target membrane  perinuclear region of cytoplasm  recycling endosome  
Pathways : BIOCARTARab GTPases Mark Targets In The Endocytotic Machinery [Genes]   
Other databases
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
PubGeneRAB8A
iHOPRAB8A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:33:45 CEST 2013
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