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RAB8B (RAB8B, member RAS oncogene family)

Identity

Other alias-
HGNC (Hugo) RAB8B
LocusID (NCBI) 51762
Atlas_Id 42010
Location 15q22.2  [Link to chromosome band 15q22]
Location_base_pair Starts at 63189529 and ends at 63267774 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAB8B (15q22.2) / ANXA2 (15q22.2)RAB8B (15q22.2) / STK19 (6p21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAB8B   30273
Cards
Entrez_Gene (NCBI)RAB8B  51762  RAB8B, member RAS oncogene family
Aliases
GeneCards (Weizmann)RAB8B
Ensembl hg19 (Hinxton)ENSG00000166128 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166128 [Gene_View]  chr15:63189529-63267774 [Contig_View]  RAB8B [Vega]
ICGC DataPortalENSG00000166128
TCGA cBioPortalRAB8B
AceView (NCBI)RAB8B
Genatlas (Paris)RAB8B
WikiGenes51762
SOURCE (Princeton)RAB8B
Genetics Home Reference (NIH)RAB8B
Genomic and cartography
GoldenPath hg38 (UCSC)RAB8B  -     chr15:63189529-63267774 +  15q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB8B  -     15q22.2   [Description]    (hg19-Feb_2009)
EnsemblRAB8B - 15q22.2 [CytoView hg19]  RAB8B - 15q22.2 [CytoView hg38]
Mapping of homologs : NCBIRAB8B [Mapview hg19]  RAB8B [Mapview hg38]
OMIM613532   
Gene and transcription
Genbank (Entrez)AB038995 AK001111 AK095444 AK297598 AL133607
RefSeq transcript (Entrez)NM_016530
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB8B
Cluster EST : UnigeneHs.389733 [ NCBI ]
CGAP (NCI)Hs.389733
Alternative Splicing GalleryENSG00000166128
Gene ExpressionRAB8B [ NCBI-GEO ]   RAB8B [ EBI - ARRAY_EXPRESS ]   RAB8B [ SEEK ]   RAB8B [ MEM ]
Gene Expression Viewer (FireBrowse)RAB8B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51762
GTEX Portal (Tissue expression)RAB8B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92930   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92930  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92930
Splice isoforms : SwissVarQ92930
PhosPhoSitePlusQ92930
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB8B
DMDM Disease mutations51762
Blocks (Seattle)RAB8B
SuperfamilyQ92930
Human Protein AtlasENSG00000166128
Peptide AtlasQ92930
HPRD11476
IPIIPI00024282   IPI00903040   IPI01013645   
Protein Interaction databases
DIP (DOE-UCLA)Q92930
IntAct (EBI)Q92930
FunCoupENSG00000166128
BioGRIDRAB8B
STRING (EMBL)RAB8B
ZODIACRAB8B
Ontologies - Pathways
QuickGOQ92930
Ontology : AmiGOGTPase activity  receptor binding  protein binding  GTP binding  nucleoplasm  mitochondrion  endosome  peroxisomal membrane  plasma membrane  vesicle docking involved in exocytosis  synaptic vesicle  protein secretion  nuclear body  GDP binding  antigen processing and presentation  phagocytic vesicle membrane  TPR domain binding  positive regulation of cell projection organization  adherens junction organization  intracellular membrane-bounded organelle  protein import into peroxisome membrane  phagocytic vesicle  perinuclear region of cytoplasm  cell tip  positive regulation of corticotropin secretion  recycling endosome membrane  cilium assembly  membrane organization  extracellular exosome  protein localization to plasma membrane  
Ontology : EGO-EBIGTPase activity  receptor binding  protein binding  GTP binding  nucleoplasm  mitochondrion  endosome  peroxisomal membrane  plasma membrane  vesicle docking involved in exocytosis  synaptic vesicle  protein secretion  nuclear body  GDP binding  antigen processing and presentation  phagocytic vesicle membrane  TPR domain binding  positive regulation of cell projection organization  adherens junction organization  intracellular membrane-bounded organelle  protein import into peroxisome membrane  phagocytic vesicle  perinuclear region of cytoplasm  cell tip  positive regulation of corticotropin secretion  recycling endosome membrane  cilium assembly  membrane organization  extracellular exosome  protein localization to plasma membrane  
NDEx NetworkRAB8B
Atlas of Cancer Signalling NetworkRAB8B
Wikipedia pathwaysRAB8B
Orthology - Evolution
OrthoDB51762
GeneTree (enSembl)ENSG00000166128
Phylogenetic Trees/Animal Genes : TreeFamRAB8B
HOVERGENQ92930
HOGENOMQ92930
Homologs : HomoloGeneRAB8B
Homology/Alignments : Family Browser (UCSC)RAB8B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB8B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB8B
dbVarRAB8B
ClinVarRAB8B
1000_GenomesRAB8B 
Exome Variant ServerRAB8B
ExAC (Exome Aggregation Consortium)RAB8B (select the gene name)
Genetic variants : HAPMAP51762
Genomic Variants (DGV)RAB8B [DGVbeta]
DECIPHERRAB8B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB8B 
Mutations
ICGC Data PortalRAB8B 
TCGA Data PortalRAB8B 
Broad Tumor PortalRAB8B
OASIS PortalRAB8B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB8B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAB8B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RAB8B
DgiDB (Drug Gene Interaction Database)RAB8B
DoCM (Curated mutations)RAB8B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB8B (select a term)
intoGenRAB8B
Cancer3DRAB8B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613532   
Orphanet
MedgenRAB8B
Genetic Testing Registry RAB8B
NextProtQ92930 [Medical]
TSGene51762
GENETestsRAB8B
Target ValidationRAB8B
Huge Navigator RAB8B [HugePedia]
snp3D : Map Gene to Disease51762
BioCentury BCIQRAB8B
ClinGenRAB8B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51762
Chemical/Pharm GKB GenePA134944620
Clinical trialRAB8B
Miscellaneous
canSAR (ICR)RAB8B (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB8B
EVEXRAB8B
GoPubMedRAB8B
iHOPRAB8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:27:46 CEST 2017

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