Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RAB9A (RAB9A, member RAS oncogene family)

Identity

Alias_namesRAB9
RAB9, member RAS oncogene family
Other alias
HGNC (Hugo) RAB9A
LocusID (NCBI) 9367
Atlas_Id 42011
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 13689121 and ends at 13709826 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RAB9A (Xp22.2) / EGFL6 (Xp22.2)RAB9A (Xp22.2) / EXOC2 (6p25.3)RAB9A Xp22.2 / EGFL6 Xp22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(X;6)(p22;p25) RAB9A/EXOC2
RAB9A/EGFL6 (Xp22)
RAB9A/EGFL6 (Xp22)

External links

Nomenclature
HGNC (Hugo)RAB9A   9792
Cards
Entrez_Gene (NCBI)RAB9A  9367  RAB9A, member RAS oncogene family
AliasesRAB9
GeneCards (Weizmann)RAB9A
Ensembl hg19 (Hinxton)ENSG00000123595 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123595 [Gene_View]  ENSG00000123595 [Sequence]  chrX:13689121-13709826 [Contig_View]  RAB9A [Vega]
ICGC DataPortalENSG00000123595
TCGA cBioPortalRAB9A
AceView (NCBI)RAB9A
Genatlas (Paris)RAB9A
WikiGenes9367
SOURCE (Princeton)RAB9A
Genetics Home Reference (NIH)RAB9A
Genomic and cartography
GoldenPath hg38 (UCSC)RAB9A  -     chrX:13689121-13709826 +  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAB9A  -     Xp22.2   [Description]    (hg19-Feb_2009)
GoldenPathRAB9A - Xp22.2 [CytoView hg19]  RAB9A - Xp22.2 [CytoView hg38]
ImmunoBaseENSG00000123595
Mapping of homologs : NCBIRAB9A [Mapview hg19]  RAB9A [Mapview hg38]
OMIM300284   
Gene and transcription
Genbank (Entrez)AF498944 AK290505 BC017265 CF528703 CR450362
RefSeq transcript (Entrez)NM_001195328 NM_004251
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAB9A
Alternative Splicing GalleryENSG00000123595
Gene ExpressionRAB9A [ NCBI-GEO ]   RAB9A [ EBI - ARRAY_EXPRESS ]   RAB9A [ SEEK ]   RAB9A [ MEM ]
Gene Expression Viewer (FireBrowse)RAB9A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9367
GTEX Portal (Tissue expression)RAB9A
Human Protein AtlasENSG00000123595-RAB9A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51151   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51151  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51151
Splice isoforms : SwissVarP51151
PhosPhoSitePlusP51151
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Rab9    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RAB9A
DMDM Disease mutations9367
Blocks (Seattle)RAB9A
PDB (RSDB)1WMS   
PDB Europe1WMS   
PDB (PDBSum)1WMS   
PDB (IMB)1WMS   
Structural Biology KnowledgeBase1WMS   
SCOP (Structural Classification of Proteins)1WMS   
CATH (Classification of proteins structures)1WMS   
SuperfamilyP51151
Human Protein Atlas [tissue]ENSG00000123595-RAB9A [tissue]
Peptide AtlasP51151
HPRD02236
IPIIPI00016372   
Protein Interaction databases
DIP (DOE-UCLA)P51151
IntAct (EBI)P51151
FunCoupENSG00000123595
BioGRIDRAB9A
STRING (EMBL)RAB9A
ZODIACRAB9A
Ontologies - Pathways
QuickGOP51151
Ontology : AmiGOGTPase activity  GTPase activity  protein binding  GTP binding  lysosome  lysosome  late endosome  late endosome  endoplasmic reticulum membrane  cytosol  plasma membrane  intracellular protein transport  GDP binding  transport vesicle  phagocytic vesicle membrane  Rab protein signal transduction  trans-Golgi network membrane  regulation of protein localization  retrograde transport, endosome to Golgi  melanosome  identical protein binding  phagocytic vesicle  phagocytic vesicle  positive regulation of exocytosis  negative regulation by host of symbiont molecular function  extracellular exosome  
Ontology : EGO-EBIGTPase activity  GTPase activity  protein binding  GTP binding  lysosome  lysosome  late endosome  late endosome  endoplasmic reticulum membrane  cytosol  plasma membrane  intracellular protein transport  GDP binding  transport vesicle  phagocytic vesicle membrane  Rab protein signal transduction  trans-Golgi network membrane  regulation of protein localization  retrograde transport, endosome to Golgi  melanosome  identical protein binding  phagocytic vesicle  phagocytic vesicle  positive regulation of exocytosis  negative regulation by host of symbiont molecular function  extracellular exosome  
Pathways : KEGGMeasles   
NDEx NetworkRAB9A
Atlas of Cancer Signalling NetworkRAB9A
Wikipedia pathwaysRAB9A
Orthology - Evolution
OrthoDB9367
GeneTree (enSembl)ENSG00000123595
Phylogenetic Trees/Animal Genes : TreeFamRAB9A
HOGENOMP51151
Homologs : HomoloGeneRAB9A
Homology/Alignments : Family Browser (UCSC)RAB9A
Gene fusions - Rearrangements
Fusion : MitelmanRAB9A/EGFL6 [Xp22.2/Xp22.2]  
Fusion : MitelmanRAB9A/EXOC2 [Xp22.2/6p25.3]  [t(X;6)(p22;p25)]  
Fusion PortalRAB9A Xp22.2 EGFL6 Xp22.2 LUSC
Fusion : QuiverRAB9A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAB9A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAB9A
dbVarRAB9A
ClinVarRAB9A
1000_GenomesRAB9A 
Exome Variant ServerRAB9A
ExAC (Exome Aggregation Consortium)ENSG00000123595
GNOMAD BrowserENSG00000123595
Varsome BrowserRAB9A
Genetic variants : HAPMAP9367
Genomic Variants (DGV)RAB9A [DGVbeta]
DECIPHERRAB9A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAB9A 
Mutations
ICGC Data PortalRAB9A 
TCGA Data PortalRAB9A 
Broad Tumor PortalRAB9A
OASIS PortalRAB9A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAB9A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRAB9A
Mutations and Diseases : HGMDRAB9A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAB9A
DgiDB (Drug Gene Interaction Database)RAB9A
DoCM (Curated mutations)RAB9A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAB9A (select a term)
intoGenRAB9A
Cancer3DRAB9A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300284   
Orphanet
DisGeNETRAB9A
MedgenRAB9A
Genetic Testing Registry RAB9A
NextProtP51151 [Medical]
TSGene9367
GENETestsRAB9A
Target ValidationRAB9A
Huge Navigator RAB9A [HugePedia]
snp3D : Map Gene to Disease9367
BioCentury BCIQRAB9A
ClinGenRAB9A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9367
Chemical/Pharm GKB GenePA34152
Clinical trialRAB9A
Miscellaneous
canSAR (ICR)RAB9A (select the gene name)
HarmonizomeRAB9A
DataMed IndexRAB9A
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAB9A
EVEXRAB9A
GoPubMedRAB9A
iHOPRAB9A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 10 12:30:06 CEST 2020
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