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RABGGTB (Rab geranylgeranyltransferase beta subunit)

Identity

Other aliasGGTB
HGNC (Hugo) RABGGTB
LocusID (NCBI) 5876
Atlas_Id 72463
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 75786194 and ends at 75795090 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MSH4 (1p31.1) / RABGGTB (1p31.1)RABGGTB (1p31.1) / ACADM (1p31.1)RABGGTB (1p31.1) / FOXJ3 (1p34.2)
RABGGTB (1p31.1) / GDI2 (10p15.1)RABGGTB (1p31.1) / HDLBP (2q37.3)RABGGTB (1p31.1) / PCLO (7q21.11)
RABGGTB (1p31.1) / RABGGTB (1p31.1)RABGGTB (1p31.1) / SLC44A5 (1p31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RABGGTB   9796
Cards
Entrez_Gene (NCBI)RABGGTB  5876  Rab geranylgeranyltransferase beta subunit
AliasesGGTB
GeneCards (Weizmann)RABGGTB
Ensembl hg19 (Hinxton)ENSG00000137955 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137955 [Gene_View]  chr1:75786194-75795090 [Contig_View]  RABGGTB [Vega]
ICGC DataPortalENSG00000137955
TCGA cBioPortalRABGGTB
AceView (NCBI)RABGGTB
Genatlas (Paris)RABGGTB
WikiGenes5876
SOURCE (Princeton)RABGGTB
Genetics Home Reference (NIH)RABGGTB
Genomic and cartography
GoldenPath hg38 (UCSC)RABGGTB  -     chr1:75786194-75795090 +  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RABGGTB  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblRABGGTB - 1p31.1 [CytoView hg19]  RABGGTB - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBIRABGGTB [Mapview hg19]  RABGGTB [Mapview hg38]
OMIM179080   
Gene and transcription
Genbank (Entrez)AB209023 AK127197 AK128861 AK293057 BC020790
RefSeq transcript (Entrez)NM_004582
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RABGGTB
Cluster EST : UnigeneHs.78948 [ NCBI ]
CGAP (NCI)Hs.78948
Alternative Splicing GalleryENSG00000137955
Gene ExpressionRABGGTB [ NCBI-GEO ]   RABGGTB [ EBI - ARRAY_EXPRESS ]   RABGGTB [ SEEK ]   RABGGTB [ MEM ]
Gene Expression Viewer (FireBrowse)RABGGTB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5876
GTEX Portal (Tissue expression)RABGGTB
Human Protein AtlasENSG00000137955-RABGGTB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53611   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53611  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53611
Splice isoforms : SwissVarP53611
Catalytic activity : Enzyme2.5.1.60 [ Enzyme-Expasy ]   2.5.1.602.5.1.60 [ IntEnz-EBI ]   2.5.1.60 [ BRENDA ]   2.5.1.60 [ KEGG ]   
PhosPhoSitePlusP53611
Domains : Interpro (EBI)PFTB_repeat    Ptb1    Terpenoid_cyclase/PrenylTrfase   
Domain families : Pfam (Sanger)Prenyltrans (PF00432)   
Domain families : Pfam (NCBI)pfam00432   
Conserved Domain (NCBI)RABGGTB
DMDM Disease mutations5876
Blocks (Seattle)RABGGTB
SuperfamilyP53611
Human Protein Atlas [tissue]ENSG00000137955-RABGGTB [tissue]
Peptide AtlasP53611
HPRD01532
IPIIPI00295849   IPI01013423   IPI00556444   IPI00514956   
Protein Interaction databases
DIP (DOE-UCLA)P53611
IntAct (EBI)P53611
FunCoupENSG00000137955
BioGRIDRABGGTB
STRING (EMBL)RABGGTB
ZODIACRABGGTB
Ontologies - Pathways
QuickGOP53611
Ontology : AmiGORab geranylgeranyltransferase activity  Rab geranylgeranyltransferase activity  protein binding  cytosol  plasma membrane  Rab-protein geranylgeranyltransferase complex  Rab-protein geranylgeranyltransferase complex  cellular protein modification process  visual perception  zinc ion binding  Rab GTPase binding  protein geranylgeranylation  protein geranylgeranylation  regulation of apoptotic process  
Ontology : EGO-EBIRab geranylgeranyltransferase activity  Rab geranylgeranyltransferase activity  protein binding  cytosol  plasma membrane  Rab-protein geranylgeranyltransferase complex  Rab-protein geranylgeranyltransferase complex  cellular protein modification process  visual perception  zinc ion binding  Rab GTPase binding  protein geranylgeranylation  protein geranylgeranylation  regulation of apoptotic process  
NDEx NetworkRABGGTB
Atlas of Cancer Signalling NetworkRABGGTB
Wikipedia pathwaysRABGGTB
Orthology - Evolution
OrthoDB5876
GeneTree (enSembl)ENSG00000137955
Phylogenetic Trees/Animal Genes : TreeFamRABGGTB
HOVERGENP53611
HOGENOMP53611
Homologs : HomoloGeneRABGGTB
Homology/Alignments : Family Browser (UCSC)RABGGTB
Gene fusions - Rearrangements
Tumor Fusion PortalRABGGTB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRABGGTB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RABGGTB
dbVarRABGGTB
ClinVarRABGGTB
1000_GenomesRABGGTB 
Exome Variant ServerRABGGTB
ExAC (Exome Aggregation Consortium)ENSG00000137955
GNOMAD BrowserENSG00000137955
Genetic variants : HAPMAP5876
Genomic Variants (DGV)RABGGTB [DGVbeta]
DECIPHERRABGGTB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRABGGTB 
Mutations
ICGC Data PortalRABGGTB 
TCGA Data PortalRABGGTB 
Broad Tumor PortalRABGGTB
OASIS PortalRABGGTB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRABGGTB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRABGGTB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RABGGTB
DgiDB (Drug Gene Interaction Database)RABGGTB
DoCM (Curated mutations)RABGGTB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RABGGTB (select a term)
intoGenRABGGTB
Cancer3DRABGGTB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM179080   
Orphanet
DisGeNETRABGGTB
MedgenRABGGTB
Genetic Testing Registry RABGGTB
NextProtP53611 [Medical]
TSGene5876
GENETestsRABGGTB
Target ValidationRABGGTB
Huge Navigator RABGGTB [HugePedia]
snp3D : Map Gene to Disease5876
BioCentury BCIQRABGGTB
ClinGenRABGGTB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5876
Chemical/Pharm GKB GenePA34157
Clinical trialRABGGTB
Miscellaneous
canSAR (ICR)RABGGTB (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRABGGTB
EVEXRABGGTB
GoPubMedRABGGTB
iHOPRABGGTB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:09:07 CET 2017

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