RABL3 (RAB, member of RAS oncogene family like 3)

2003-12-01  

Identity

HGNC
RABL3
LOCATION
3q13.33
LOCUSID
285282
ALIAS
PNCA5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 285282
MIM: 618542
HGNC: 18072
Ensembl: ENSG00000144840

Variants:

dbSNP: 285282
ClinVar: 285282
TCGA: ENSG00000144840
COSMIC: RABL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144840ENST00000273375Q5HYI8
ENSG00000144840ENST00000465022F8WDC7
ENSG00000144840ENST00000473654F8WF50
ENSG00000144840ENST00000481015H7C533
ENSG00000144840ENST00000483733C9JXM3
ENSG00000144840ENST00000485161F8WAX9

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
287394962017Overexpression of Rabl3 and Cullin7 is associated with pathogenesis and poor prognosis in hepatocellular carcinoma.4
205966302010Evaluation of the novel gene Rabl3 in the regulation of proliferation and motility in human cancer cells.0
271642972016High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy.0
284434982017The overexpression of Rabl3 is associated with pathogenesis and clinicopathologic variables in hepatocellular carcinoma.0
314063472019Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.0

Citation

Dessen P

RABL3 (RAB, member of RAS oncogene family like 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42017/rabl3