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RAD51B (RAD51 paralog B)

Identity

Alias (NCBI)R51H2
RAD51L1
REC2
HGNC (Hugo) RAD51B
HGNC Alias symbREC2
hREC2
R51H2
HGNC Previous nameRAD51L1
HGNC Previous nameRAD51 (S. cerevisiae)-like 1
 RAD51-like 1 (S. cerevisiae)
 RAD51 homolog B (S. cerevisiae)
LocusID (NCBI) 5890
Atlas_Id 52276
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 67819779 and ends at 68478093 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AFF1 (4q21.3) / RAD51B (14q24.1)ASAP1 (8q24.21) / RAD51B (14q24.1)ATAD2 (8q24.13) / RAD51B (14q24.1)
CEP170 (1q43) / RAD51B (14q24.1)CHD9 (16q12.2) / RAD51B (14q24.1)DCAF5 (14q24.1) / RAD51B (14q24.1)
HMGA2 (12q14.3) / RAD51B (14q24.1)MPP5 (14q23.3) / RAD51B (14q24.1)NECTIN2 (19q13.32) / RAD51B (14q24.1)
NPC2 (14q24.3) / RAD51B (14q24.1)PCNX1 (14q24.2) / RAD51B (14q24.1)RAB40C (16p13.3) / RAD51B (14q24.1)
RAD51B (14q24.1) / BMP2 (20p12.3)RAD51B (14q24.1) / DACT1 (14q23.1)RAD51B (14q24.1) / DCAF5 (14q24.1)
RAD51B (14q24.1) / FNDC3B (3q26.31)RAD51B (14q24.1) / HMGA2 (12q14.3)RAD51B (14q24.1) / KMT2A (11q23.3)
RAD51B (14q24.1) / OPHN1 (Xq12)RAD51B (14q24.1) / PLAG1 (8q12.1)RAD51B (14q24.1) / RAD51B (14q24.1)
RAD51B (14q24.1) / RPSAP52 (12q14.3)RAD51B (14q24.1) / RRAGB (Xp11.21)RAD51B (14q24.1) / UVRAG (11q13.5)
SLC39A9 (14q24.1) / RAD51B (14q24.1)SUSD6 (14q24.1) / RAD51B (14q24.1)UVRAG (11q13.5) / RAD51B (14q24.1)
ZFYVE26 (14q24.1) / RAD51B (14q24.1)ZZZ3 (1p31.1) / RAD51B (14q24.1)RAD51B 14q24.1 / HMGA2 12q14.3
ASAP1 8q24.21 / RAD51B 14q24.1ATAD2 8q24.13 / RAD51B 14q24.1CHD9 16q12.2 / RAD51B 14q24.1
KIAA0247 RAD51B 14q24.1MPP5 14q23.3 / RAD51B 14q24.1NPC2 14q24.3 / RAD51B 14q24.1
PCNX 14q24.2 / RAD51B 14q24.1RAB40C 16p13.3 / RAD51B 14q24.1RAD51B 14q24.1 / DACT1 14q23.1
RAD51B 14q24.1 / DCAF5 14q24.1RAD51B 14q24.1 / UVRAG 11q13.5SLC39A9 14q24.1 / RAD51B 14q24.1
UVRAG 11q13.5 / RAD51B 14q24.1ZFYVE26 14q24.1 / RAD51B 14q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;14)(q43;q24) CEP170/RAD51B
t(4;14)(q21;q24) AFF1/RAD51B
t(11;14)(q23;q24) RAD51B/KMT2A


External links

Nomenclature
HGNC (Hugo)RAD51B   9822
Cards
Entrez_Gene (NCBI)RAD51B    RAD51 paralog B
AliasesR51H2; RAD51L1; REC2
GeneCards (Weizmann)RAD51B
Ensembl hg19 (Hinxton)ENSG00000182185 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182185 [Gene_View]  ENSG00000182185 [Sequence]  chr14:67819779-68478093 [Contig_View]  RAD51B [Vega]
ICGC DataPortalENSG00000182185
TCGA cBioPortalRAD51B
AceView (NCBI)RAD51B
Genatlas (Paris)RAD51B
SOURCE (Princeton)RAD51B
Genetics Home Reference (NIH)RAD51B
Genomic and cartography
GoldenPath hg38 (UCSC)RAD51B  -     chr14:67819779-68478093 +  14q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAD51B  -     14q24.1   [Description]    (hg19-Feb_2009)
GoldenPathRAD51B - 14q24.1 [CytoView hg19]  RAD51B - 14q24.1 [CytoView hg38]
ImmunoBaseENSG00000182185
Genome Data Viewer NCBIRAD51B [Mapview hg19]  
OMIM602948   
Gene and transcription
Genbank (Entrez)AK130466 AK309787 AK310686 AL597484 BC030219
RefSeq transcript (Entrez)NM_001321809 NM_001321810 NM_001321812 NM_001321814 NM_001321815 NM_001321817 NM_001321818 NM_001321819 NM_001321821 NM_002877 NM_133509 NM_133510
Consensus coding sequences : CCDS (NCBI)RAD51B
Gene ExpressionRAD51B [ NCBI-GEO ]   RAD51B [ EBI - ARRAY_EXPRESS ]   RAD51B [ SEEK ]   RAD51B [ MEM ]
Gene Expression Viewer (FireBrowse)RAD51B [ Firebrowse - Broad ]
GenevisibleExpression of RAD51B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5890
GTEX Portal (Tissue expression)RAD51B
Human Protein AtlasENSG00000182185-RAD51B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)RAD51B
Human Protein Atlas [tissue]ENSG00000182185-RAD51B [tissue]
HPRD04255
Protein Interaction databases
BioGRIDRAD51B
STRING (EMBL)RAD51B
ZODIACRAD51B
Ontologies - Pathways
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRAD51B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:28:05 CEST 2021

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