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RAD54B (RAD54 homolog B (S. cerevisiae))

Identity

Alias_symbol (synonym)RDH54
Other alias
HGNC (Hugo) RAD54B
LocusID (NCBI) 25788
Atlas_Id 42030
Location 8q22.1  [Link to chromosome band 8q22]
Location_base_pair Starts at 95439940 and ends at 95487343 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
COL22A1 (8q24.23) / RAD54B (8q22.1)PPM1D (17q23.2) / RAD54B (8q22.1)RAD54B (8q22.1) / BRIP1 (17q23.2)
RAD54B (8q22.1) / HNRNPA2B1 (7p15.2)RAD54B (8q22.1) / IKZF3 (17q12)RAD54B (8q22.1) / MATN2 (8q22.1)
TRIQK (8q22.1) / RAD54B (8q22.1)C8orf83 RAD54B 8q22.1COL22A1 8q24.23 / RAD54B 8q22.1
RAD54B 8q22.1 / MATN2 8q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAD54B   17228
Cards
Entrez_Gene (NCBI)RAD54B  25788  RAD54 homolog B (S. cerevisiae)
AliasesRDH54
GeneCards (Weizmann)RAD54B
Ensembl hg19 (Hinxton)ENSG00000197275 [Gene_View]  chr8:95439940-95487343 [Contig_View]  RAD54B [Vega]
Ensembl hg38 (Hinxton)ENSG00000197275 [Gene_View]  chr8:95439940-95487343 [Contig_View]  RAD54B [Vega]
ICGC DataPortalENSG00000197275
TCGA cBioPortalRAD54B
AceView (NCBI)RAD54B
Genatlas (Paris)RAD54B
WikiGenes25788
SOURCE (Princeton)RAD54B
Genetics Home Reference (NIH)RAD54B
Genomic and cartography
GoldenPath hg19 (UCSC)RAD54B  -     chr8:95439940-95487343 -  8q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RAD54B  -     8q22.1   [Description]    (hg38-Dec_2013)
EnsemblRAD54B - 8q22.1 [CytoView hg19]  RAD54B - 8q22.1 [CytoView hg38]
Mapping of homologs : NCBIRAD54B [Mapview hg19]  RAD54B [Mapview hg38]
OMIM604289   605027   
Gene and transcription
Genbank (Entrez)AF086020 AF112481 AK290437 AK307516 AL133578
RefSeq transcript (Entrez)NM_001205262 NM_001205263 NM_006550 NM_012415 NM_134434
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_012878 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)RAD54B
Cluster EST : UnigeneHs.744229 [ NCBI ]
CGAP (NCI)Hs.744229
Alternative Splicing GalleryENSG00000197275
Gene ExpressionRAD54B [ NCBI-GEO ]   RAD54B [ EBI - ARRAY_EXPRESS ]   RAD54B [ SEEK ]   RAD54B [ MEM ]
Gene Expression Viewer (FireBrowse)RAD54B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25788
GTEX Portal (Tissue expression)RAD54B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y620   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y620  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y620
Splice isoforms : SwissVarQ9Y620
Catalytic activity : Enzyme3.6.4.- [ Enzyme-Expasy ]   3.6.4.-3.6.4.- [ IntEnz-EBI ]   3.6.4.- [ BRENDA ]   3.6.4.- [ KEGG ]   
PhosPhoSitePlusQ9Y620
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)Helicase_ATP-bd    Helicase_C    P-loop_NTPase    SNF2_N   
Domain families : Pfam (Sanger)Helicase_C (PF00271)    SNF2_N (PF00176)   
Domain families : Pfam (NCBI)pfam00271    pfam00176   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)RAD54B
DMDM Disease mutations25788
Blocks (Seattle)RAD54B
SuperfamilyQ9Y620
Human Protein AtlasENSG00000197275
Peptide AtlasQ9Y620
HPRD05049
IPIIPI00431401   IPI00431402   IPI00018281   IPI01012948   IPI00796482   IPI00797041   IPI00973902   IPI00981780   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y620
IntAct (EBI)Q9Y620
FunCoupENSG00000197275
BioGRIDRAD54B
STRING (EMBL)RAD54B
ZODIACRAD54B
Ontologies - Pathways
QuickGOQ9Y620
Ontology : AmiGOdouble-strand break repair via homologous recombination  DNA binding  DNA helicase activity  RNA helicase activity  ATP binding  nucleus  mitotic recombination  reciprocal meiotic recombination  determination of adult lifespan  response to ionizing radiation  DNA translocase activity  DNA duplex unwinding  response to drug  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  DNA binding  DNA helicase activity  RNA helicase activity  ATP binding  nucleus  mitotic recombination  reciprocal meiotic recombination  determination of adult lifespan  response to ionizing radiation  DNA translocase activity  DNA duplex unwinding  response to drug  
Pathways : KEGGHomologous recombination   
NDEx NetworkRAD54B
Atlas of Cancer Signalling NetworkRAD54B
Wikipedia pathwaysRAD54B
Orthology - Evolution
OrthoDB25788
GeneTree (enSembl)ENSG00000197275
Phylogenetic Trees/Animal Genes : TreeFamRAD54B
HOVERGENQ9Y620
HOGENOMQ9Y620
Homologs : HomoloGeneRAD54B
Homology/Alignments : Family Browser (UCSC)RAD54B
Gene fusions - Rearrangements
Fusion : MitelmanCOL22A1/RAD54B [8q24.23/8q22.1]  [t(8;8)(q22;q24)]  
Fusion : MitelmanRAD54B/MATN2 [8q22.1/8q22.1]  [t(8;8)(q22;q22)]  
Fusion : MitelmanTRIQK/RAD54B [8q22.1/8q22.1]  [t(8;8)(q22;q22)]  
Fusion: TCGAC8orf83 RAD54B 8q22.1 BRCA
Fusion: TCGACOL22A1 8q24.23 RAD54B 8q22.1 KIRC
Fusion: TCGARAD54B 8q22.1 MATN2 8q22.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAD54B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAD54B
dbVarRAD54B
ClinVarRAD54B
1000_GenomesRAD54B 
Exome Variant ServerRAD54B
ExAC (Exome Aggregation Consortium)RAD54B (select the gene name)
Genetic variants : HAPMAP25788
Genomic Variants (DGV)RAD54B [DGVbeta]
DECIPHER (Syndromes)8:95439940-95487343  ENSG00000197275
CONAN: Copy Number AnalysisRAD54B 
Mutations
ICGC Data PortalRAD54B 
TCGA Data PortalRAD54B 
Broad Tumor PortalRAD54B
OASIS PortalRAD54B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAD54B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAD54B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAD54B
DgiDB (Drug Gene Interaction Database)RAD54B
DoCM (Curated mutations)RAD54B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAD54B (select a term)
intoGenRAD54B
Cancer3DRAD54B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604289    605027   
Orphanet
MedgenRAD54B
Genetic Testing Registry RAD54B
NextProtQ9Y620 [Medical]
TSGene25788
GENETestsRAD54B
Huge Navigator RAD54B [HugePedia]
snp3D : Map Gene to Disease25788
BioCentury BCIQRAD54B
ClinGenRAD54B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25788
Chemical/Pharm GKB GenePA134927202
Clinical trialRAD54B
Miscellaneous
canSAR (ICR)RAD54B (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAD54B
EVEXRAD54B
GoPubMedRAD54B
iHOPRAD54B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:45 CEST 2017

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