RAD54L (RAD54 like)

2003-02-01  

Identity

HGNC
RAD54L
LOCATION
1p34.1
LOCUSID
8438
ALIAS
HR54,RAD54A,hHR54,hRAD54
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8438
MIM: 603615
HGNC: 9826
Ensembl: ENSG00000085999

Variants:

dbSNP: 8438
ClinVar: 8438
TCGA: ENSG00000085999
COSMIC: RAD54L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000085999ENST00000371975Q92698
ENSG00000085999ENST00000442598Q92698
ENSG00000085999ENST00000459678A0A087WV39
ENSG00000085999ENST00000463715A0A087WWG5
ENSG00000085999ENST00000469835V9GYX6
ENSG00000085999ENST00000472889A0A087WTB0
ENSG00000085999ENST00000473251A0A087X124
ENSG00000085999ENST00000476687A0A087WVW5
ENSG00000085999ENST00000488942V9GYD3
ENSG00000085999ENST00000493032A0A087WW72
ENSG00000085999ENST00000493985A0A087WW72
ENSG00000085999ENST00000655446A0A590UJJ7
ENSG00000085999ENST00000657122A0A590UJQ8
ENSG00000085999ENST00000661701A0A590UJ90
ENSG00000085999ENST00000669994A0A590UJ71
ENSG00000085999ENST00000671528Q92698

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Homologous recombinationKEGGko03440
Homologous recombinationKEGGhsa03440

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
168621292006Rad54 protein promotes branch migration of Holliday junctions.93
165204632006Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.57
176608332007Rad54 dissociates homologous recombination intermediates by branch migration.56
165406872006Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival.38
174176552007Homology-driven chromatin remodeling by human RAD54.37
191477822009DNA repair gene polymorphisms and risk of pancreatic cancer.34
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
175451452007Interactions of human rad54 protein with branched DNA molecules.22
182703392008Comprehensive analysis of DNA repair gene variants and risk of meningioma.22

Citation

Dessen P

RAD54L (RAD54 like)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/348/rad54l