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RAD54L2 (RAD54 like 2)

Identity

Alias_symbol (synonym)KIAA0809
SRISNF2L
ARIP4
Other aliasHSPC325
HGNC (Hugo) RAD54L2
LocusID (NCBI) 23132
Atlas_Id 54570
Location 3p21.2  [Link to chromosome band 3p21]
Location_base_pair Starts at 51538683 and ends at 51668660 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IARS (9q22.31) / RAD54L2 (3p21.2)RAD54L2 (3p21.2) / ERC2 (3p14.3)RAD54L2 (3p21.2) / PTPRS (19p13.3)
RAD54L2 (3p21.2) / VPRBP (3p21.2)RAD54L2 3p21.2 / ERC2 3p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(3;3)(p14;p21) RAD54L2/ERC2

External links

Nomenclature
HGNC (Hugo)RAD54L2   29123
Cards
Entrez_Gene (NCBI)RAD54L2  23132  RAD54 like 2
AliasesARIP4; HSPC325; SRISNF2L
GeneCards (Weizmann)RAD54L2
Ensembl hg19 (Hinxton)ENSG00000164080 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164080 [Gene_View]  ENSG00000164080 [Sequence]  chr3:51538683-51668660 [Contig_View]  RAD54L2 [Vega]
ICGC DataPortalENSG00000164080
TCGA cBioPortalRAD54L2
AceView (NCBI)RAD54L2
Genatlas (Paris)RAD54L2
WikiGenes23132
SOURCE (Princeton)RAD54L2
Genetics Home Reference (NIH)RAD54L2
Genomic and cartography
GoldenPath hg38 (UCSC)RAD54L2  -     chr3:51538683-51668660 +  3p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAD54L2  -     3p21.2   [Description]    (hg19-Feb_2009)
EnsemblRAD54L2 - 3p21.2 [CytoView hg19]  RAD54L2 - 3p21.2 [CytoView hg38]
Mapping of homologs : NCBIRAD54L2 [Mapview hg19]  RAD54L2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB018352 AF088021 AF161443 AK023824 AK025049
RefSeq transcript (Entrez)NM_001322253 NM_001322256 NM_001322257 NM_015106
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAD54L2
Cluster EST : UnigeneHs.659486 [ NCBI ]
CGAP (NCI)Hs.659486
Alternative Splicing GalleryENSG00000164080
Gene ExpressionRAD54L2 [ NCBI-GEO ]   RAD54L2 [ EBI - ARRAY_EXPRESS ]   RAD54L2 [ SEEK ]   RAD54L2 [ MEM ]
Gene Expression Viewer (FireBrowse)RAD54L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23132
GTEX Portal (Tissue expression)RAD54L2
Human Protein AtlasENSG00000164080-RAD54L2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4B4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4B4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4B4
Splice isoforms : SwissVarQ9Y4B4
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.123.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
PhosPhoSitePlusQ9Y4B4
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)Helicase_ATP-bd    Helicase_C    P-loop_NTPase    SNF2_N   
Domain families : Pfam (Sanger)Helicase_C (PF00271)    SNF2_N (PF00176)   
Domain families : Pfam (NCBI)pfam00271    pfam00176   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)RAD54L2
DMDM Disease mutations23132
Blocks (Seattle)RAD54L2
SuperfamilyQ9Y4B4
Human Protein Atlas [tissue]ENSG00000164080-RAD54L2 [tissue]
Peptide AtlasQ9Y4B4
HPRD10018
IPIIPI00294787   IPI00916394   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4B4
IntAct (EBI)Q9Y4B4
FunCoupENSG00000164080
BioGRIDRAD54L2
STRING (EMBL)RAD54L2
ZODIACRAD54L2
Ontologies - Pathways
QuickGOQ9Y4B4
Ontology : AmiGODNA binding  helicase activity  protein binding  ATP binding  nucleus  
Ontology : EGO-EBIDNA binding  helicase activity  protein binding  ATP binding  nucleus  
NDEx NetworkRAD54L2
Atlas of Cancer Signalling NetworkRAD54L2
Wikipedia pathwaysRAD54L2
Orthology - Evolution
OrthoDB23132
GeneTree (enSembl)ENSG00000164080
Phylogenetic Trees/Animal Genes : TreeFamRAD54L2
HOGENOMQ9Y4B4
Homologs : HomoloGeneRAD54L2
Homology/Alignments : Family Browser (UCSC)RAD54L2
Gene fusions - Rearrangements
Fusion : MitelmanRAD54L2/ERC2 [3p21.2/3p14.3]  
Fusion : MitelmanRAD54L2/VPRBP [3p21.2/3p21.2]  [t(3;3)(p21;p21)]  
Fusion PortalRAD54L2 3p21.2 ERC2 3p14.3 BRCA
Fusion : QuiverRAD54L2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAD54L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAD54L2
dbVarRAD54L2
ClinVarRAD54L2
1000_GenomesRAD54L2 
Exome Variant ServerRAD54L2
ExAC (Exome Aggregation Consortium)ENSG00000164080
GNOMAD BrowserENSG00000164080
Varsome BrowserRAD54L2
Genetic variants : HAPMAP23132
Genomic Variants (DGV)RAD54L2 [DGVbeta]
DECIPHERRAD54L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAD54L2 
Mutations
ICGC Data PortalRAD54L2 
TCGA Data PortalRAD54L2 
Broad Tumor PortalRAD54L2
OASIS PortalRAD54L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAD54L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAD54L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAD54L2
DgiDB (Drug Gene Interaction Database)RAD54L2
DoCM (Curated mutations)RAD54L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAD54L2 (select a term)
intoGenRAD54L2
Cancer3DRAD54L2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRAD54L2
MedgenRAD54L2
Genetic Testing Registry RAD54L2
NextProtQ9Y4B4 [Medical]
TSGene23132
GENETestsRAD54L2
Target ValidationRAD54L2
Huge Navigator RAD54L2 [HugePedia]
snp3D : Map Gene to Disease23132
BioCentury BCIQRAD54L2
ClinGenRAD54L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23132
Chemical/Pharm GKB GenePA143485591
Clinical trialRAD54L2
Miscellaneous
canSAR (ICR)RAD54L2 (select the gene name)
DataMed IndexRAD54L2
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAD54L2
EVEXRAD54L2
GoPubMedRAD54L2
iHOPRAD54L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Feb 14 16:53:12 CET 2019
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