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RAE1 (ribonucleic acid export 1)

Identity

Alias_namesRAE1 (RNA export 1, S.pombe) homolog
RAE1 RNA export 1 homolog (S. pombe)
Alias_symbol (synonym)Mnrp41
Other aliasMIG14
MRNP41
dJ481F12.3
dJ800J21.1
HGNC (Hugo) RAE1
LocusID (NCBI) 8480
Atlas_Id 54571
Location 20q13.31  [Link to chromosome band 20q13]
Location_base_pair Starts at 57351562 and ends at 57378463 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BMP7 (20q13.31) / RAE1 (20q13.31)ELMO2 (20q13.12) / RAE1 (20q13.31)KDM5A (12p13.33) / RAE1 (20q13.31)
NFATC2 (20q13.2) / RAE1 (20q13.31)RBM38 (20q13.31) / RAE1 (20q13.31)SLC9A8 (20q13.13) / RAE1 (20q13.31)
STX16 (20q13.32) / RAE1 (20q13.31)KDM5A 12p13.33 / RAE1 20q13.31RBM38 20q13.31 / RAE1 20q13.31
SLC9A8 20q13.13 / RAE1 20q13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  inv(11)(p15q23) NUP98/KMT2A
t(4;11)(q23;p15) NUP98/RAP1GDS1


External links

Nomenclature
HGNC (Hugo)RAE1   9828
Cards
Entrez_Gene (NCBI)RAE1  8480  ribonucleic acid export 1
AliasesMIG14; MRNP41; Mnrp41; dJ481F12.3; 
dJ800J21.1
GeneCards (Weizmann)RAE1
Ensembl hg19 (Hinxton)ENSG00000101146 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101146 [Gene_View]  chr20:57351562-57378463 [Contig_View]  RAE1 [Vega]
ICGC DataPortalENSG00000101146
TCGA cBioPortalRAE1
AceView (NCBI)RAE1
Genatlas (Paris)RAE1
WikiGenes8480
SOURCE (Princeton)RAE1
Genetics Home Reference (NIH)RAE1
Genomic and cartography
GoldenPath hg38 (UCSC)RAE1  -     chr20:57351562-57378463 +  20q13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAE1  -     20q13.31   [Description]    (hg19-Feb_2009)
EnsemblRAE1 - 20q13.31 [CytoView hg19]  RAE1 - 20q13.31 [CytoView hg38]
Mapping of homologs : NCBIRAE1 [Mapview hg19]  RAE1 [Mapview hg38]
OMIM603343   
Gene and transcription
Genbank (Entrez)AI341915 AK055170 AK126024 AK292247 AK307966
RefSeq transcript (Entrez)NM_001015885 NM_003610
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAE1
Cluster EST : UnigeneHs.371698 [ NCBI ]
CGAP (NCI)Hs.371698
Alternative Splicing GalleryENSG00000101146
Gene ExpressionRAE1 [ NCBI-GEO ]   RAE1 [ EBI - ARRAY_EXPRESS ]   RAE1 [ SEEK ]   RAE1 [ MEM ]
Gene Expression Viewer (FireBrowse)RAE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8480
GTEX Portal (Tissue expression)RAE1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78406   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78406  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78406
Splice isoforms : SwissVarP78406
PhosPhoSitePlusP78406
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)RAE1
DMDM Disease mutations8480
Blocks (Seattle)RAE1
PDB (SRS)3MMY    4OWR   
PDB (PDBSum)3MMY    4OWR   
PDB (IMB)3MMY    4OWR   
PDB (RSDB)3MMY    4OWR   
Structural Biology KnowledgeBase3MMY    4OWR   
SCOP (Structural Classification of Proteins)3MMY    4OWR   
CATH (Classification of proteins structures)3MMY    4OWR   
SuperfamilyP78406
Human Protein AtlasENSG00000101146
Peptide AtlasP78406
HPRD11939
IPIIPI00019733   IPI00794643   IPI00797295   IPI00982313   IPI01010974   
Protein Interaction databases
DIP (DOE-UCLA)P78406
IntAct (EBI)P78406
FunCoupENSG00000101146
BioGRIDRAE1
STRING (EMBL)RAE1
ZODIACRAE1
Ontologies - Pathways
QuickGOP78406
Ontology : AmiGOfibrillar center  RNA binding  nucleus  nuclear envelope  nuclear envelope  nuclear pore  cytoplasm  mRNA export from nucleus  tRNA export from nucleus  mitotic nuclear envelope disassembly  microtubule binding  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  cellular response to organic cyclic compound  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIfibrillar center  RNA binding  nucleus  nuclear envelope  nuclear envelope  nuclear pore  cytoplasm  mRNA export from nucleus  tRNA export from nucleus  mitotic nuclear envelope disassembly  microtubule binding  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  cellular response to organic cyclic compound  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport    Influenza A   
NDEx NetworkRAE1
Atlas of Cancer Signalling NetworkRAE1
Wikipedia pathwaysRAE1
Orthology - Evolution
OrthoDB8480
GeneTree (enSembl)ENSG00000101146
Phylogenetic Trees/Animal Genes : TreeFamRAE1
HOVERGENP78406
HOGENOMP78406
Homologs : HomoloGeneRAE1
Homology/Alignments : Family Browser (UCSC)RAE1
Gene fusions - Rearrangements
Fusion : MitelmanELMO2/RAE1 [20q13.12/20q13.31]  [t(20;20)(q13;q13)]  
Fusion : MitelmanKDM5A/RAE1 [12p13.33/20q13.31]  [t(12;20)(p13;q13)]  
Fusion : MitelmanRBM38/RAE1 [20q13.31/20q13.31]  [t(20;20)(q13;q13)]  
Fusion : MitelmanSLC9A8/RAE1 [20q13.13/20q13.31]  [t(20;20)(q13;q13)]  
Fusion : MitelmanSTX16/RAE1 [20q13.32/20q13.31]  [t(20;20)(q13;q13)]  
Fusion: TCGAKDM5A 12p13.33 RAE1 20q13.31 LUAD
Fusion: TCGARBM38 20q13.31 RAE1 20q13.31 BRCA
Fusion: TCGASLC9A8 20q13.13 RAE1 20q13.31 BRCA
Fusion Cancer (Beijing)BMP7 [20q13.31]  -  RAE1 [20q13.31]  [FUSC000517]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAE1
dbVarRAE1
ClinVarRAE1
1000_GenomesRAE1 
Exome Variant ServerRAE1
ExAC (Exome Aggregation Consortium)RAE1 (select the gene name)
Genetic variants : HAPMAP8480
Genomic Variants (DGV)RAE1 [DGVbeta]
DECIPHERRAE1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAE1 
Mutations
ICGC Data PortalRAE1 
TCGA Data PortalRAE1 
Broad Tumor PortalRAE1
OASIS PortalRAE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAE1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAE1
DgiDB (Drug Gene Interaction Database)RAE1
DoCM (Curated mutations)RAE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAE1 (select a term)
intoGenRAE1
Cancer3DRAE1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603343   
Orphanet
MedgenRAE1
Genetic Testing Registry RAE1
NextProtP78406 [Medical]
TSGene8480
GENETestsRAE1
Target ValidationRAE1
Huge Navigator RAE1 [HugePedia]
snp3D : Map Gene to Disease8480
BioCentury BCIQRAE1
ClinGenRAE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8480
Chemical/Pharm GKB GenePA34182
Clinical trialRAE1
Miscellaneous
canSAR (ICR)RAE1 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAE1
EVEXRAE1
GoPubMedRAE1
iHOPRAE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:27:55 CEST 2017

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