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RALA (v-ral simian leukemia viral oncogene homolog A (ras related))

Identity

Other namesRAL
HGNC (Hugo) RALA
LocusID (NCBI) 5898
Location 7p14.1
Location_base_pair Starts at 39663152 and ends at 39747723 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RALA   9839
Cards
Entrez_Gene (NCBI)RALA  5898  v-ral simian leukemia viral oncogene homolog A (ras related)
GeneCards (Weizmann)RALA
Ensembl (Hinxton)ENSG00000006451 [Gene_View]  chr7:39663152-39747723 [Contig_View]  RALA [Vega]
ICGC DataPortalENSG00000006451
cBioPortalRALA
AceView (NCBI)RALA
Genatlas (Paris)RALA
WikiGenes5898
SOURCE (Princeton)NM_005402
Genomic and cartography
GoldenPath (UCSC)RALA  -  7p14.1   chr7:39663152-39747723 +  7p14.1   [Description]    (hg19-Feb_2009)
EnsemblRALA - 7p14.1 [CytoView]
Mapping of homologs : NCBIRALA [Mapview]
OMIM179550   
Gene and transcription
Genbank (Entrez)AF086082 AF493910 AK026850 AK308109 AU132355
RefSeq transcript (Entrez)NM_005402
RefSeq genomic (Entrez)AC_000139 NC_000007 NC_018918 NT_007819 NW_001839004 NW_004929329
Consensus coding sequences : CCDS (NCBI)RALA
Cluster EST : UnigeneHs.6906 [ NCBI ]
CGAP (NCI)Hs.6906
Alternative Splicing : Fast-db (Paris)GSHG0027303
Alternative Splicing GalleryENSG00000006451
Gene ExpressionRALA [ NCBI-GEO ]     RALA [ SEEK ]   RALA [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11233 (Uniprot)
NextProtP11233  [Medical]
With graphics : InterProP11233
Splice isoforms : SwissVarP11233 (Swissvar)
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase [organisation]   Ral [organisation]   Small_GTP-bd_dom [organisation]   Small_GTPase [organisation]   Small_GTPase_Ras [organisation]  
Related proteins : CluSTrP11233
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAS (SM00173)  
DMDM Disease mutations5898
Blocks (Seattle)P11233
PDB (SRS)1UAD    1ZC3    1ZC4    2A78    2A9K    2BOV   
PDB (PDBSum)1UAD    1ZC3    1ZC4    2A78    2A9K    2BOV   
PDB (IMB)1UAD    1ZC3    1ZC4    2A78    2A9K    2BOV   
PDB (RSDB)1UAD    1ZC3    1ZC4    2A78    2A9K    2BOV   
Human Protein AtlasENSG00000006451 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP11233
HPRD01549
IPIIPI00217519   IPI00927929   IPI00927712   
Protein Interaction databases
DIP (DOE-UCLA)P11233
IntAct (EBI)P11233
FunCoupENSG00000006451
BioGRIDRALA
InParanoidP11233
Interologous Interaction database P11233
IntegromeDBRALA
STRING (EMBL)RALA
Ontologies - Pathways
Ontology : AmiGOcytokinesis  GTPase activity  protein binding  GTP binding  plasma membrane  GTP catabolic process  exocytosis  chemotaxis  signal transduction  Ras protein signal transduction  cell surface  viral process  regulation of exocytosis  endocytic vesicle  midbody  cytoplasmic vesicle membrane  actin cytoskeleton reorganization  Edg-2 lysophosphatidic acid receptor binding  cleavage furrow  neurotrophin TRK receptor signaling pathway  positive regulation of filopodium assembly  membrane raft localization  membrane organization  extracellular vesicular exosome  
Ontology : EGO-EBIcytokinesis  GTPase activity  protein binding  GTP binding  plasma membrane  GTP catabolic process  exocytosis  chemotaxis  signal transduction  Ras protein signal transduction  cell surface  viral process  regulation of exocytosis  endocytic vesicle  midbody  cytoplasmic vesicle membrane  actin cytoskeleton reorganization  Edg-2 lysophosphatidic acid receptor binding  cleavage furrow  neurotrophin TRK receptor signaling pathway  positive regulation of filopodium assembly  membrane raft localization  membrane organization  extracellular vesicular exosome  
Pathways : BIOCARTARas Signaling Pathway [Genes]   
Pathways : KEGGRas signaling pathway    Rap1 signaling pathway    Pathways in cancer    Pancreatic cancer   
Protein Interaction DatabaseRALA
Wikipedia pathwaysRALA
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RALA
snp3D : Map Gene to Disease5898
SNP (GeneSNP Utah)RALA
SNP : HGBaseRALA
Genetic variants : HAPMAPRALA
Exome VariantRALA
1000_GenomesRALA 
ICGC programENSG00000006451 
Somatic Mutations in Cancer : COSMICRALA 
CONAN: Copy Number AnalysisRALA 
Mutations and Diseases : HGMDRALA
Genomic VariantsRALA  RALA [DGVbeta]
dbVarRALA
ClinVarRALA
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM179550   
MedgenRALA
GENETestsRALA
Disease Genetic AssociationRALA
Huge Navigator RALA [HugePedia]  RALA [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneRALA
Homology/Alignments : Family Browser (UCSC)RALA
Phylogenetic Trees/Animal Genes : TreeFamRALA
Chemical/Protein Interactions : CTD5898
Chemical/Pharm GKB GenePA34197
Clinical trialRALA
Cancer Resource (Charite)ENSG00000006451
Other databases
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
CoreMineRALA
iHOPRALA
OncoSearchRALA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:12:27 CEST 2014

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