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RALB (RAS like proto-oncogene B)

Identity

Alias_namesv-ral simian leukemia viral oncogene homolog B
Other alias-
HGNC (Hugo) RALB
LocusID (NCBI) 5899
Atlas_Id 42036
Location 2q14.2  [Link to chromosome band 2q14]
Location_base_pair Starts at 120252838 and ends at 120294710 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C7orf25 (7p14.1) / RALB (2q14.2)RALB (2q14.2) / RALB (2q14.2)TFF1 (21q22.3) / RALB (2q14.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RALB   9840
Cards
Entrez_Gene (NCBI)RALB  5899  RAS like proto-oncogene B
Aliases
GeneCards (Weizmann)RALB
Ensembl hg19 (Hinxton)ENSG00000144118 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144118 [Gene_View]  chr2:120252838-120294710 [Contig_View]  RALB [Vega]
ICGC DataPortalENSG00000144118
TCGA cBioPortalRALB
AceView (NCBI)RALB
Genatlas (Paris)RALB
WikiGenes5899
SOURCE (Princeton)RALB
Genetics Home Reference (NIH)RALB
Genomic and cartography
GoldenPath hg38 (UCSC)RALB  -     chr2:120252838-120294710 +  2q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RALB  -     2q14.2   [Description]    (hg19-Feb_2009)
EnsemblRALB - 2q14.2 [CytoView hg19]  RALB - 2q14.2 [CytoView hg38]
Mapping of homologs : NCBIRALB [Mapview hg19]  RALB [Mapview hg38]
OMIM179551   
Gene and transcription
Genbank (Entrez)AF493911 AK127675 AK303214 AK304588 AK312453
RefSeq transcript (Entrez)NM_002881
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RALB
Cluster EST : UnigeneHs.469820 [ NCBI ]
CGAP (NCI)Hs.469820
Alternative Splicing GalleryENSG00000144118
Gene ExpressionRALB [ NCBI-GEO ]   RALB [ EBI - ARRAY_EXPRESS ]   RALB [ SEEK ]   RALB [ MEM ]
Gene Expression Viewer (FireBrowse)RALB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5899
GTEX Portal (Tissue expression)RALB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11234   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11234  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11234
Splice isoforms : SwissVarP11234
PhosPhoSitePlusP11234
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Ral    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RALB
DMDM Disease mutations5899
Blocks (Seattle)RALB
PDB (SRS)2KE5    2KWI   
PDB (PDBSum)2KE5    2KWI   
PDB (IMB)2KE5    2KWI   
PDB (RSDB)2KE5    2KWI   
Structural Biology KnowledgeBase2KE5    2KWI   
SCOP (Structural Classification of Proteins)2KE5    2KWI   
CATH (Classification of proteins structures)2KE5    2KWI   
SuperfamilyP11234
Human Protein AtlasENSG00000144118
Peptide AtlasP11234
HPRD01550
IPIIPI01015571   IPI00004397   IPI00444204   IPI00926453   IPI00925636   IPI00925885   
Protein Interaction databases
DIP (DOE-UCLA)P11234
IntAct (EBI)P11234
FunCoupENSG00000144118
BioGRIDRALB
STRING (EMBL)RALB
ZODIACRALB
Ontologies - Pathways
QuickGOP11234
Ontology : AmiGOexocyst  cytokinesis  regulation of exocyst assembly  positive regulation of protein phosphorylation  GTPase activity  protein binding  GTP binding  GTP binding  autophagosome  plasma membrane  apoptotic process  signal transduction  Ras protein signal transduction  cellular response to starvation  GDP binding  midbody  ubiquitin protein ligase binding  negative regulation of protein binding  positive regulation of protein binding  ATPase binding  regulation of exocyst localization  extracellular exosome  cellular response to exogenous dsRNA  positive regulation of protein serine/threonine kinase activity  positive regulation of autophagosome assembly  
Ontology : EGO-EBIexocyst  cytokinesis  regulation of exocyst assembly  positive regulation of protein phosphorylation  GTPase activity  protein binding  GTP binding  GTP binding  autophagosome  plasma membrane  apoptotic process  signal transduction  Ras protein signal transduction  cellular response to starvation  GDP binding  midbody  ubiquitin protein ligase binding  negative regulation of protein binding  positive regulation of protein binding  ATPase binding  regulation of exocyst localization  extracellular exosome  cellular response to exogenous dsRNA  positive regulation of protein serine/threonine kinase activity  positive regulation of autophagosome assembly  
Pathways : KEGGRas signaling pathway    Rap1 signaling pathway    Pathways in cancer    Pancreatic cancer   
NDEx NetworkRALB
Atlas of Cancer Signalling NetworkRALB
Wikipedia pathwaysRALB
Orthology - Evolution
OrthoDB5899
GeneTree (enSembl)ENSG00000144118
Phylogenetic Trees/Animal Genes : TreeFamRALB
HOVERGENP11234
HOGENOMP11234
Homologs : HomoloGeneRALB
Homology/Alignments : Family Browser (UCSC)RALB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRALB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RALB
dbVarRALB
ClinVarRALB
1000_GenomesRALB 
Exome Variant ServerRALB
ExAC (Exome Aggregation Consortium)RALB (select the gene name)
Genetic variants : HAPMAP5899
Genomic Variants (DGV)RALB [DGVbeta]
DECIPHERRALB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRALB 
Mutations
ICGC Data PortalRALB 
TCGA Data PortalRALB 
Broad Tumor PortalRALB
OASIS PortalRALB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRALB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRALB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RALB
DgiDB (Drug Gene Interaction Database)RALB
DoCM (Curated mutations)RALB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RALB (select a term)
intoGenRALB
Cancer3DRALB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM179551   
Orphanet
MedgenRALB
Genetic Testing Registry RALB
NextProtP11234 [Medical]
TSGene5899
GENETestsRALB
Huge Navigator RALB [HugePedia]
snp3D : Map Gene to Disease5899
BioCentury BCIQRALB
ClinGenRALB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5899
Chemical/Pharm GKB GenePA34198
Clinical trialRALB
Miscellaneous
canSAR (ICR)RALB (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRALB
EVEXRALB
GoPubMedRALB
iHOPRALB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:34:09 CEST 2017

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