RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2)

2013-05-01  

Identity

HGNC
LOCATION
20p11.23
LOCUSID
ALIAS
AS250,C20orf74,bA287B20.1,dJ1049G11,dJ1049G11.4,p220
FUSION GENES

Other Information

Locus ID:

NCBI: 57186
MIM: 618836
HGNC: 16207
Ensembl: ENSG00000188559

Variants:

dbSNP: 57186
ClinVar: 57186
TCGA: ENSG00000188559
COSMIC: RALGAPA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188559ENST00000202677Q2PPJ7
ENSG00000188559ENST00000427175H7BZA8
ENSG00000188559ENST00000430436H7C1F9
ENSG00000188559ENST00000495793A0A3B3IS41
ENSG00000188559ENST00000620717A0A087WYA8

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
224507452013Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer.22
164903462006Adipocytes contain a novel complex similar to the tuberous sclerosis complex.13
310582832019Downregulation of RalGTPase-activating protein promotes invasion of prostatic epithelial cells and progression from intraepithelial neoplasia to cancer during prostate carcinogenesis.2

Citation

Dessen P

RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53283/ralgapa2