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RALGAPB (Ral GTPase activating protein non-catalytic beta subunit)

Identity

Alias_namesKIAA1219
KIAA1219
Alias_symbol (synonym)DKFZp781M2411
RalGAPbeta
Other alias
HGNC (Hugo) RALGAPB
LocusID (NCBI) 57148
Atlas_Id 54889
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 38472806 and ends at 38578861 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COPB2 (3q23) / RALGAPB (20q11.23)MCM5 (22q12.3) / RALGAPB (20q11.23)RALGAPB (20q11.23) / CNBD2 (20q11.23)
RALGAPB (20q11.23) / CTNNBL1 (20q11.23)RALGAPB (20q11.23) / EPB41L1 (20q11.23)RALGAPB (20q11.23) / RPRD1B (20q11.23)
RALGAPB (20q11.23) / SCNN1G (16p12.2)MCM5 22q12.3 / RALGAPB 20q11.23RALGAPB 20q11.23 C20orf152
RALGAPB 20q11.23 / CTNNBL1 20q11.23RALGAPB 20q11.23 / EPB41L1 20q11.23RALGAPB 20q11.23 / RPRD1B 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RALGAPB   29221
Cards
Entrez_Gene (NCBI)RALGAPB  57148  Ral GTPase activating protein non-catalytic beta subunit
AliasesKIAA1219; RalGAPbeta
GeneCards (Weizmann)RALGAPB
Ensembl hg19 (Hinxton)ENSG00000170471 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170471 [Gene_View]  chr20:38472806-38578861 [Contig_View]  RALGAPB [Vega]
ICGC DataPortalENSG00000170471
TCGA cBioPortalRALGAPB
AceView (NCBI)RALGAPB
Genatlas (Paris)RALGAPB
WikiGenes57148
SOURCE (Princeton)RALGAPB
Genetics Home Reference (NIH)RALGAPB
Genomic and cartography
GoldenPath hg38 (UCSC)RALGAPB  -     chr20:38472806-38578861 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RALGAPB  -     20q11.23   [Description]    (hg19-Feb_2009)
EnsemblRALGAPB - 20q11.23 [CytoView hg19]  RALGAPB - 20q11.23 [CytoView hg38]
Mapping of homologs : NCBIRALGAPB [Mapview hg19]  RALGAPB [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB033045 AB621815 AK026771 AK123576 AK125260
RefSeq transcript (Entrez)NM_001282917 NM_001282918 NM_020336
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RALGAPB
Cluster EST : UnigeneHs.598850 [ NCBI ]
CGAP (NCI)Hs.598850
Alternative Splicing GalleryENSG00000170471
Gene ExpressionRALGAPB [ NCBI-GEO ]   RALGAPB [ EBI - ARRAY_EXPRESS ]   RALGAPB [ SEEK ]   RALGAPB [ MEM ]
Gene Expression Viewer (FireBrowse)RALGAPB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57148
GTEX Portal (Tissue expression)RALGAPB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86X10   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86X10  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86X10
Splice isoforms : SwissVarQ86X10
PhosPhoSitePlusQ86X10
Domaine pattern : Prosite (Expaxy)RAPGAP (PS50085)   
Domains : Interpro (EBI)Rap_GAP_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)RALGAPB
DMDM Disease mutations57148
Blocks (Seattle)RALGAPB
SuperfamilyQ86X10
Human Protein AtlasENSG00000170471
Peptide AtlasQ86X10
HPRD11133
IPIIPI00409601   IPI00748653   IPI00410120   IPI00936060   IPI00977336   IPI00410121   
Protein Interaction databases
DIP (DOE-UCLA)Q86X10
IntAct (EBI)Q86X10
FunCoupENSG00000170471
BioGRIDRALGAPB
STRING (EMBL)RALGAPB
ZODIACRALGAPB
Ontologies - Pathways
QuickGOQ86X10
Ontology : AmiGOGTPase activator activity  GTPase activator activity  protein heterodimerization activity  protein heterodimerization activity  regulation of small GTPase mediated signal transduction  activation of GTPase activity  activation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  GTPase activator activity  protein heterodimerization activity  protein heterodimerization activity  regulation of small GTPase mediated signal transduction  activation of GTPase activity  activation of GTPase activity  
NDEx NetworkRALGAPB
Atlas of Cancer Signalling NetworkRALGAPB
Wikipedia pathwaysRALGAPB
Orthology - Evolution
OrthoDB57148
GeneTree (enSembl)ENSG00000170471
Phylogenetic Trees/Animal Genes : TreeFamRALGAPB
HOVERGENQ86X10
HOGENOMQ86X10
Homologs : HomoloGeneRALGAPB
Homology/Alignments : Family Browser (UCSC)RALGAPB
Gene fusions - Rearrangements
Fusion : MitelmanMCM5/RALGAPB [22q12.3/20q11.23]  [t(20;22)(q11;q12)]  
Fusion : MitelmanRALGAPB/CNBD2 [20q11.23/20q11.23]  [t(20;20)(q11;q11)]  
Fusion : MitelmanRALGAPB/CTNNBL1 [20q11.23/20q11.23]  [t(20;20)(q11;q11)]  
Fusion : MitelmanRALGAPB/EPB41L1 [20q11.23/20q11.23]  [t(20;20)(q11;q11)]  
Fusion : MitelmanRALGAPB/RPRD1B [20q11.23/20q11.23]  [t(20;20)(q11;q11)]  
Fusion: TCGAMCM5 22q12.3 RALGAPB 20q11.23 BRCA
Fusion: TCGARALGAPB 20q11.23 C20orf152 BRCA
Fusion: TCGARALGAPB 20q11.23 CTNNBL1 20q11.23 BRCA
Fusion: TCGARALGAPB 20q11.23 EPB41L1 20q11.23 BRCA
Fusion: TCGARALGAPB 20q11.23 RPRD1B 20q11.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRALGAPB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RALGAPB
dbVarRALGAPB
ClinVarRALGAPB
1000_GenomesRALGAPB 
Exome Variant ServerRALGAPB
ExAC (Exome Aggregation Consortium)RALGAPB (select the gene name)
Genetic variants : HAPMAP57148
Genomic Variants (DGV)RALGAPB [DGVbeta]
DECIPHERRALGAPB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRALGAPB 
Mutations
ICGC Data PortalRALGAPB 
TCGA Data PortalRALGAPB 
Broad Tumor PortalRALGAPB
OASIS PortalRALGAPB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRALGAPB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRALGAPB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RALGAPB
DgiDB (Drug Gene Interaction Database)RALGAPB
DoCM (Curated mutations)RALGAPB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RALGAPB (select a term)
intoGenRALGAPB
Cancer3DRALGAPB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRALGAPB
Genetic Testing Registry RALGAPB
NextProtQ86X10 [Medical]
TSGene57148
GENETestsRALGAPB
Huge Navigator RALGAPB [HugePedia]
snp3D : Map Gene to Disease57148
BioCentury BCIQRALGAPB
ClinGenRALGAPB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57148
Chemical/Pharm GKB GenePA165392608
Clinical trialRALGAPB
Miscellaneous
canSAR (ICR)RALGAPB (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRALGAPB
EVEXRALGAPB
GoPubMedRALGAPB
iHOPRALGAPB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:34:10 CEST 2017

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