Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RALGDS (ral guanine nucleotide dissociation stimulator)

Identity

Alias_symbol (synonym)RGF
RalGEF
RGDS
Other alias
HGNC (Hugo) RALGDS
LocusID (NCBI) 5900
Atlas_Id 42038
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 133097720 and ends at 133149220 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CIITA (16p13.13) / RALGDS (9q34.2)RALGDS (9q34.2) / CIITA (16p13.13)RALGDS (9q34.2) / MAMLD1 (Xq28)
RALGDS (9q34.2) / RALGDS (9q34.2)TRAF5 (1q32.3) / RALGDS (9q34.2)WDR74 (11q12.3) / RALGDS (9q34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RALGDS   9842
Cards
Entrez_Gene (NCBI)RALGDS  5900  ral guanine nucleotide dissociation stimulator
AliasesRGDS; RGF; RalGEF
GeneCards (Weizmann)RALGDS
Ensembl hg19 (Hinxton)ENSG00000160271 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160271 [Gene_View]  chr9:133097720-133149220 [Contig_View]  RALGDS [Vega]
ICGC DataPortalENSG00000160271
TCGA cBioPortalRALGDS
AceView (NCBI)RALGDS
Genatlas (Paris)RALGDS
WikiGenes5900
SOURCE (Princeton)RALGDS
Genetics Home Reference (NIH)RALGDS
Genomic and cartography
GoldenPath hg38 (UCSC)RALGDS  -     chr9:133097720-133149220 -  9q34.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RALGDS  -     9q34.13   [Description]    (hg19-Feb_2009)
EnsemblRALGDS - 9q34.13 [CytoView hg19]  RALGDS - 9q34.13 [CytoView hg38]
Mapping of homologs : NCBIRALGDS [Mapview hg19]  RALGDS [Mapview hg38]
OMIM601619   
Gene and transcription
Genbank (Entrez)AB037729 AF027169 AF295773 AK000242 AK024575
RefSeq transcript (Entrez)NM_001042368 NM_001271774 NM_001271775 NM_001271776 NM_006266
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RALGDS
Cluster EST : UnigeneHs.106185 [ NCBI ]
CGAP (NCI)Hs.106185
Alternative Splicing GalleryENSG00000160271
Gene ExpressionRALGDS [ NCBI-GEO ]   RALGDS [ EBI - ARRAY_EXPRESS ]   RALGDS [ SEEK ]   RALGDS [ MEM ]
Gene Expression Viewer (FireBrowse)RALGDS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5900
GTEX Portal (Tissue expression)RALGDS
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12967   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12967  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12967
Splice isoforms : SwissVarQ12967
PhosPhoSitePlusQ12967
Domaine pattern : Prosite (Expaxy)RA (PS50200)    RASGEF (PS00720)    RASGEF_CAT (PS50009)    RASGEF_NTER (PS50212)   
Domains : Interpro (EBI)RA_dom    RalGDS    Ras-like_Gua-exchang_fac_N    Ras_G-nucl-exch_fac_CS    Ras_GEF_dom    RASGEF_cat_dom    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)RA (PF00788)    RasGEF (PF00617)    RasGEF_N (PF00618)   
Domain families : Pfam (NCBI)pfam00788    pfam00617    pfam00618   
Domain families : Smart (EMBL)RA (SM00314)  RasGEF (SM00147)  RasGEFN (SM00229)  
Conserved Domain (NCBI)RALGDS
DMDM Disease mutations5900
Blocks (Seattle)RALGDS
PDB (SRS)1RAX    2B3A    2RGF    3KH0   
PDB (PDBSum)1RAX    2B3A    2RGF    3KH0   
PDB (IMB)1RAX    2B3A    2RGF    3KH0   
PDB (RSDB)1RAX    2B3A    2RGF    3KH0   
Structural Biology KnowledgeBase1RAX    2B3A    2RGF    3KH0   
SCOP (Structural Classification of Proteins)1RAX    2B3A    2RGF    3KH0   
CATH (Classification of proteins structures)1RAX    2B3A    2RGF    3KH0   
SuperfamilyQ12967
Human Protein AtlasENSG00000160271
Peptide AtlasQ12967
HPRD03371
IPIIPI00290395   IPI00902660   IPI00922861   IPI00640603   IPI00514974   IPI00550528   IPI01014166   
Protein Interaction databases
DIP (DOE-UCLA)Q12967
IntAct (EBI)Q12967
FunCoupENSG00000160271
BioGRIDRALGDS
STRING (EMBL)RALGDS
ZODIACRALGDS
Ontologies - Pathways
QuickGOQ12967
Ontology : AmiGOguanyl-nucleotide exchange factor activity  protein binding  nucleus  cytosol  cytosol  brush border  Ras protein signal transduction  GTPase regulator activity  GTPase regulator activity  positive regulation of GTPase activity  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  protein binding  nucleus  cytosol  cytosol  brush border  Ras protein signal transduction  GTPase regulator activity  GTPase regulator activity  positive regulation of GTPase activity  
Pathways : BIOCARTARas Signaling Pathway [Genes]   
Pathways : KEGGRas signaling pathway    Rap1 signaling pathway    Pathways in cancer    Colorectal cancer    Pancreatic cancer   
NDEx NetworkRALGDS
Atlas of Cancer Signalling NetworkRALGDS
Wikipedia pathwaysRALGDS
Orthology - Evolution
OrthoDB5900
GeneTree (enSembl)ENSG00000160271
Phylogenetic Trees/Animal Genes : TreeFamRALGDS
HOVERGENQ12967
HOGENOMQ12967
Homologs : HomoloGeneRALGDS
Homology/Alignments : Family Browser (UCSC)RALGDS
Gene fusions - Rearrangements
Fusion : MitelmanCIITA/RALGDS [16p13.13/9q34.2]  [t(9;16)(q34;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRALGDS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RALGDS
dbVarRALGDS
ClinVarRALGDS
1000_GenomesRALGDS 
Exome Variant ServerRALGDS
ExAC (Exome Aggregation Consortium)RALGDS (select the gene name)
Genetic variants : HAPMAP5900
Genomic Variants (DGV)RALGDS [DGVbeta]
DECIPHERRALGDS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRALGDS 
Mutations
ICGC Data PortalRALGDS 
TCGA Data PortalRALGDS 
Broad Tumor PortalRALGDS
OASIS PortalRALGDS [ Somatic mutations - Copy number]
Cancer Gene: CensusRALGDS 
Somatic Mutations in Cancer : COSMICRALGDS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRALGDS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RALGDS
DgiDB (Drug Gene Interaction Database)RALGDS
DoCM (Curated mutations)RALGDS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RALGDS (select a term)
intoGenRALGDS
Cancer3DRALGDS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601619   
Orphanet
MedgenRALGDS
Genetic Testing Registry RALGDS
NextProtQ12967 [Medical]
TSGene5900
GENETestsRALGDS
Target ValidationRALGDS
Huge Navigator RALGDS [HugePedia]
snp3D : Map Gene to Disease5900
BioCentury BCIQRALGDS
ClinGenRALGDS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5900
Chemical/Pharm GKB GenePA34200
Clinical trialRALGDS
Miscellaneous
canSAR (ICR)RALGDS (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRALGDS
EVEXRALGDS
GoPubMedRALGDS
iHOPRALGDS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:27:58 CEST 2017

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