RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2)

2007-04-01  

Identity

HGNC
RALGPS2
LOCATION
1q25.2
LOCUSID
55103
ALIAS
dJ595C2.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55103
MIM: 617819
HGNC: 30279
Ensembl: ENSG00000116191

Variants:

dbSNP: 55103
ClinVar: 55103
TCGA: ENSG00000116191
COSMIC: RALGPS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116191ENST00000324778A0A0A0MR31
ENSG00000116191ENST00000367632H0Y338
ENSG00000116191ENST00000367634Q86X27
ENSG00000116191ENST00000367635Q86X27
ENSG00000116191ENST00000415888H7C2H2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
292084602018RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells.8
271493772016RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases.6

Citation

Dessen P

RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47435/ralgps2